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Listar por autor "González Martínez, Miguel Ángel"

Mostrando ítems 1-20 de 22

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A Label-Free Interdigitated Microelectrodes Immunosensor for Pesticide Detection

Marrakchi, Mouna; Campos Sánchez, Inmaculada; Helali, S.; Mejri, N.; Soto Camino, Juan; González Martínez, Miguel Ángel; Hamdi, M.; Abdelghani, A. (American Scientific Publishers, 2011)

[EN] A sensitive, simple and label-free immunosensor for atrazine detection was developed. The immunosensor was based on antibody physisorption as immobilization technique. This technique was proposed as a cost-effective ...
An Immunosensor for the Automatic Determination of the Antifouling Agent Irgarol 1051 in Natural Waters

González Martínez, Miguel Ángel; Penalva Villegas, José; Puchades, Rosa; Maquieira Catala, Ángel; Ballesteros, Berta; Marco, Maria Pilar; Barceló, Damià (American Chemical Society, 1998-09)

[EN] The development of an immunosensor for analysis of the antifouling agent Irgarol 1051 (2-methylthio-4-tert-butylamin-6-cyclopropylamin-s-triazine) is described. The immunosensor is based on a heterogeneous competitive ...
Aprendizaje activo dirigido a la selección de las condiciones cromatográficas en HPLC

Tortajada Genaro, Luis Antonio; González Martínez, Miguel Ángel (2022-07-06)

La cromatografía líquida de alta resolución (HPLC) es una de las principales técnicas instrumentales para obtener información química y molecular. Consiste en lograr el avance diferencial de las especies procedentes de una ...
Automation of Heterogeneous Enzyme Immunoassay for Atrazine. Comparison of Three Immobilization Supports

González Martínez, Miguel Ángel; Morais, Sergi; Puchades, Rosa; Maquieira Catala, Angel; Marco, M.; Barceló, D. (Springer-Verlag, 1998-05)

[EN] Intensive agriculture associated with the use of large amounts of different pesticides, together with the growing concern about the potential contamination of ground water, have brought about the need for developing ...
Biosensado de péptidos ß-amiloides basado en inmunoensayos integrados para el cribado de la enfermedad de Alzheimer

Plazas Gómez, Iker (Universitat Politècnica de València, 2024-10-14)

[ES] Las enfermedades neurodegenerativas como la enfermedad de Alzheimer tienen un alto impacto sanitario, socioeconómico y personal, y su incidencia va en aumento. Sin embargo, la capacidad actual para diagnosticarlas de ...
Biosensado en formato de micromatriz para la detección de MICRO-RNA

Sirera Conca, Belén (Universitat Politècnica de València, 2019-09-04)

[ES] La detección temprana de numerosas enfermedades, principalmente el cáncer, exige desarrollar nuevos métodos de diagnóstico con bases moleculares. En este contexto, la detección de microRNAs es importante debido a ...
Biosensors for food allergy detection according to specific IgE levels in serum

Morais, Sergi; Tortajada-Genaro, Luis Antonio; Maquieira Catala, Ángel; González Martínez, Miguel Ángel (Elsevier, 2020-06)

[EN] People respond differently to food components, which can sometimes cause dramatic and unpredictable effects, such as intolerance, toxicity and allergy, and are a major global problem today. Of all the different reactions ...
Caracterización de Agregados Proteicos Mediante Técnicas Moleculares

Rubert Albiol, Alba (Universitat Politècnica de València, 2015-09-04)

[EN] The work is devoted to characterize proteic aggregates, concretely the binding of immunoglobulins to membrane proteins, employing molecular label free methods such as dual polarization interferometry DPI. Receptor ...
Design and Characterization of ITO-Covered Resonant Nanopillars for Dual Optical and Electrochemical Sensing

Tramarin, Luca; Casquel, Rafael; Gil-Rostra, Jorge; González Martínez, Miguel Ángel; Herrero-Labrador, Raquel; Murillo, Ana María M.; Laguna, María Fé; Bañuls Polo, María-José; González-Elipe, Agustín R.; Holgado, Miguel (MDPI AG, 2022-10)

[EN] In this work we present a dual optical and electrochemical sensor based on SiO2/Si3N4 resonant nanopillars covered with an indium tin oxide (ITO) thin film. A 25-30 nm thick ITO layer deposited by magnetron sputtering ...
Development of an automated controlled-pore glass flow-through immunosensor for carbaryl

González Martínez, Miguel Ángel; Morais, Sergi; Puchades, Rosa; Maquieira Giménez, Manuel; Abad Fuentes, Antonio; Montoya Baides, Ángel (Elsevier Masson, 1997-07-30)

[EN] The application of controlled-pore glass (CPG) as solid support for immobilization of immunoreagents in order to develop flow-through immunosensors is described. Monoclonal antibodies (MAbs) to carbaryl were site-directed ...
Direct and label-free monitoring oligonucleotide immobilization, non-specific binding and DNA biorecognition

López Paz, José Luis; González Martínez, Miguel Ángel; Escorihuela Fuentes, Jorge; Bañuls Polo, Mª José; Puchades Pla, Rosa; Maquieira Catala, Ángel (Elsevier, 2014-03-01)

DNA binding chemistry on silicon surface has been investigated. Aminated oligonucleotide probes were immobilized on the chip surface by chemical silanization and further covalent attachment. The chemistries employed were ...
Dual-Polarization Interferometry: A Novel Technique To Light up the Nanomolecular World

Escorihuela Fuentes, Jorge; González Martínez, Miguel Ángel; López-Paz, José Luis; Puchades, Rosa; Maquieira Catala, Ángel; Giménez Romero, David (American Chemical Society, 2015-01-14)

[EN] The challenging lecture given in 1959 by physicist and Nobel Prize awarded R. P. Feynman: “There's plenty of room at the bottom” is considered to be the starting point for nanotechnology. With this peculiar title, ...
Evaluación de la competencia transversal “Responsabilidad ética, medioambiental y profesional” a través de una e-rúbrica en el laboratorio

Bañuls Polo, María; López Gresa, María Pilar; Cebolla Cornejo, Jaime; Díez Niclós, Mª José Teresa de Jesús; Esteras Gómez, Cristina; Ferriol Molina, María; González Martínez, Miguel Ángel; Leiva Brondo, Miguel; Llorens Molina, Juan Antonio; Merle Farinós, Hugo Basilio; Peiró Barber, Rosa María; Pérez de Castro, Ana María; Picó Sirvent, María Belén; Lisón Párraga, María Purificación (Editorial Universitat Politècnica de València, 2015-06-10)

[ES] El proceso de convergencia hacia el Espacio Europeo de Enseñanza Superior ha puesto de relieve la importancia del dominio de competencias transversales (CTs) durante la formación universitaria. Dichas competencias ...
High density Microarrays on Blu-ray discs for massive screening

Arnandis Chover, Tania; Morais Ezquerro, Sergi Beñat; González Martínez, Miguel Ángel; Puchades Pla, Rosa; Maquieira Catala, Ángel (Elsevier, 2014-01-15)

The potential and the capabilities of Blu-ray technology (discs and drives) for massive screening applications are presented. High density microarrays are fabricated onto a Blu-ray disc and applied for the determination ...
Improvement of a pesticide immunosensor performance using site-directed antibody immobilisation and carbon nanotubes

Marrakchi, Mouna; Helali, S.; Soto Camino, Juan; González Martínez, Miguel Ángel; Abdelghani, Adnane; Hamdi, Moktar (Inderscience, 2013)

The potential toxicity of pesticide residues in drinking water has meant a rigid regulation for the appearance of these pollutants. Thus, in this work, we developed a new immunosensor for atrazine detection. We focused ...
INSEL: An in silico method for optimizing and exploring biorecognition assays

Avella-Oliver, Miquel; Giménez Romero, David; Morais, Sergi; González Martínez, Miguel Ángel; Bueno, Paulo Roberto; Puchades, Rosa; Maquieira Catala, Ángel (Royal Society of Chemistry, 2013)

[EN] A practical in silico method for optimizing and exploring biointeraction-based events is developed.
Modeling of the Role of Conformational Dynamics in Kinetics of the Antigen-Antibody Interaction in Heterogeneous Phase

Giménez Romero, David; González Martínez, Miguel Ángel; Bañuls Polo, Mª José; Monzó, Isidro S.; Puchades Pla, Rosa; Maquieira Catala, Ángel (American Chemical Society, 2012-04-23)

[EN] A novel approach that may potentially be used to study biomolecular interactions including the simultaneous determination of structural and kinetic binding parameters is described in this Article for the first time. ...
Modulating receptor-ligand binding in biorecognition by setting surface wettability

Aragón Revuelta, Pilar; Noguera Murray, Patricia Silvestre; Bañuls Polo, María-José; Puchades, Rosa; Maquieira Catala, Angel; González Martínez, Miguel Ángel (Springer-Verlag, 2018)

[EN] Modulation of support wettability used for microarray format biosensing has led to an improvement of results. Hydrophobicity of glass chips was set by derivatizing with single vinyl organosilanes of different chain ...
Monoclonal antibody-based flow-through immunosensor for analysis of carbaryl

González Martínez, Miguel Ángel; Morais, Sergi; Puchades, Rosa; Maquieira Catala, Ángel; Abad Fuentes, Antonio; Montoya Baides, Ángel (American Chemical Society, 1997-07-15)

[EN] Immunosensor systems have been developed for the rapid and sensitive determination of pesticides, using the insecticide carbaryl as a model analyte. The systems are based on the principle of heterogeneous competitive ...
Prácticas de fundamentos de química

Noguera Murray, Patricia Silvestre; Aragón Revuelta, Pilar; Esteve Ciudad, Patricia; Morais Ezquerro, Sergi Beñat; Pastor Navarro, Nuria; Tortajada Genaro, Luis Antonio; González Martínez, Miguel Ángel (Editorial Universitat Politècnica de València, 2021-10-06)

Este texto está orientado a estudiantes que cursan una asignatura de química en el primer curso universitario de grados universitarios relacionados con la biotecnología o biología molecular. Dado que la teoría se comprende ...