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Listar por autor "Saiz Rodríguez, Francisco Javier"

Mostrando ítems 1-20 de 161

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3D patient-specific spinal cord computational model for SCS management: potential clinical applications

Solanes, Carmen; Dura, Jose L.; Canós, M.A.; De Andres, Jose; Marti-Bonmati, Luis; Saiz Rodríguez, Francisco Javier (IOP Publishing, 2021-06)

[EN] Objective. Although spinal cord stimulation (SCS) is an established therapy for treating neuropathic chronic pain, in tonic stimulation, postural changes, electrode migration or badly-positioned electrodes can produce ...
A Multiscale in Silico Study to Characterize the Atrial Electrical Activity of Patients With Atrial Fibrillation. A Translational Study to Guide Ablation Therapy

Sánchez Arciniegas, Jorge Patricio (Universitat Politècnica de València, 2021-07-26)

[ES] La fibrilación auricular es la arritmia cardíaca más común. Durante la fibrilación auricular, el sustrato auricular sufre una serie de cambios o remodelados a nivel eléctrico y estructural. La remodelación eléctrica ...
A three-dimensional human atrial model with fiber orientation. Electrograms and arrhythmic activation patterns relationship

Tobón Zuluaga, Catalina; Ruiz Villa, Carlos Alberto; Heidenreich, Elvio; Romero Pérez, Lucia; Hornero, Fernando; Saiz Rodríguez, Francisco Javier (Public Library of Science, 2013-02)

The most common sustained cardiac arrhythmias in humans are atrial tachyarrhythmias, mainly atrial fibrillation. Areas of complex fractionated atrial electrograms and high dominant frequency have been proposed as critical ...
A Three-Dimensional Model of the Human Atria With Heterogeneous Wall Thickness and Fibre Transmurallity - A Realistic Platform for the Study of Atrial Fibrillation

Rocher-Ventura, Sara; Martínez, Laura; López, Alejandro; Ferrer, Ana; Sánchez-Quintana, Damián; Saiz Rodríguez, Francisco Javier (IEEE, 2019-09-11)

[EN] Multiscale cardiac modelling has been increasingly used since it provides a promising framework to improve our understanding of atrial fibrillation physiopathology. In this study, we present a highly detailed ...
Algorithms for Detection of Atrial Fibrillation Sources

Félix Iglesias, Jorge Ramón (Universitat Politècnica de València, 2015-02-13)

Atrial fibrillation (AF) is a cardiac arrhythmia with significant morbidity and mortality affecting more than 10% of people over 75 years. Clinical studies demonstrate that population aging and sedentary lifestyle will ...
An Open-Circuit Indirect Calorimetry Head Hood System for Measuring Methane Emission and Energy Metabolism in Small Ruminants

Fernández Martínez, Carlos Javier; Gomis-Tena Dolz, Julio; Hernández Ferrer, Alberto; Saiz Rodríguez, Francisco Javier (MDPI AG, 2019-06-21)

[EN] Methane (CH4) is a natural by-product of microbial fermentation in the rumen and is a powerful greenhouse gas. An open-circuit indirect calorimetry system for continuous determination of CH4 and CO2 production and O-2 ...
Analisis estadistico de datos de tratamiento en la planificacion de radioterapia

Peláez Bover, Ramón (Universitat Politècnica de València, 2020-07-21)

[EN] The World Health Organization estimates that cancer was responsible for 9.6 millions deaths worldwide in 2018, becoming the second leading cause of death globally. These amount of deaths has turned cancer in one of ...
Analysis of surface electromyographic parameters for the assessment of muscle fatigue during moderate exercises

Junquera-Godoy, Isabel; Gomis-Tena Dolz, Julio; Martínez-de-Juan, José L.; Saiz Rodríguez, Francisco Javier; Prats-Boluda, Gema (Universidad de Valladolid, 2022-11-25)

[EN] Muscle fatigue is a neuromuscular phenomenon which prevents the muscles to generate the required force. Although there are multiple studies about detecting this condition with surface electromyography, this method ...
Análisis comparativo del efecto farmacológico en células ventriculares sanas y con insuficiencia cardíaca mediante métodos de modelado y simulación

Llopis Lorente, Jordi (Universitat Politècnica de València, 2018-10-10)

[ES] Uno de los posibles efectos secundarios de un fármaco es la generación de Torsade de Pointes (TdP), una taquicardia ventricular potencialmente letal, responsable de la retirada de muchos fármacos del mercado. Por ello, ...
Análisis de arritmias auriculares mediante mapeo superficial (BSM). Estudio de simulación

Muela Pérez, Jaime (Universitat Politècnica de València, 2014-01-21)
Análisis de segmentos en marcha con sensores de presión integrados en plantillas: detección automática de la marcha y análisis de diferentes patrones del andar

Maneus Salvador, Marina (Universitat Politècnica de València, 2021-10-08)

[ES] El objetivo de este proyecto es detectar las diferencias entre los patrones de marcha de dos individuos y entre las pruebas de un mismo individuo utilizando MATLAB. En primer lugar, se reorganizan los datos brutos y ...
APD, QT interval and Tx Values

Saiz Rodríguez, Francisco Javier; Sanz i Carreras, Ferran; Pastor Maeso, Manuel; Trénor Gomis, Beatriz Ana; Gomis-Tena Dolz, Julio; Cano García, Jordi; Romero Pérez, Lucia (Universitat Politècnica de València, 2017-10-31)

This repository contains four Excel 2017 files named “APD.xlsx”, “QT.xlsx”, “Tx_APD.xlsx” and “Tx_QT.xlsx”. APD.xlsx and Tx_APD.xlsx files contain three sheets (called “Epi”, “Mid” and “Endo”), whereas the rest contain ...
Aplicación de modelos computacionales multiescala de la actividad eléctrica en la predicción de cardiotoxicidad

Cano García, Jordi (Universitat Politècnica de València, 2015-06-17)

[EN] Introduction. In the risk prediction of Torsade-de-pointes arrythmia assotiated to drug intake, electric conduction multiscale models are used but, for now, a connection between dose, plasma concentration and channel ...
Application of Machine Learning to improve the efficiency of electrophysiological simulations used for the prediction of drug-induced ventricular arrhythmia

Rodriguez-Belenguer, Pablo; Kopanska, Karolina; Llopis-Lorente, Jordi; Trenor Gomis, Beatriz Ana; Saiz Rodríguez, Francisco Javier; Pastor, Manuel (Elsevier, 2023-03)

[EN] Background and Objective In silico prediction of drug-induced ventricular arrhythmia often requires computationally intensive simulations, making its application tedious and non-interactive. This inconvenience can ...
Application of Machine Learning to improve the efficiency of electrophysiological simulations used for the prediction of drug-induced ventricular arrhythmia

Rodríguez-Belenguer, Pablo; Kopańska, Karolina; Llopis Lorente, Jordi; Trénor Gomis, Beatriz Ana; Saiz Rodríguez, Francisco Javier; Pastor, Manuel (Universitat Politècnica de València, 2022-06-03)

In cardiotoxicity studies it is common to pre-compute the values of different biomarkers (my equation or TX) for a range of ion channel blockades. Since every simulation requires costly computations, to complete the matrix ...
Arrhythmogenic Effects of Genetic Mutations Affecting Potassium Channels in Human Atrial Fibrillation: A Simulation Study

Belletti, Rebecca; Romero Pérez, Lucia; Martínez-Mateu, Laura; Cherry, Elizabeth M.; Fenton, Flavio H.; Saiz Rodríguez, Francisco Javier (Frontiers Media SA, 2021-05-31)

[EN] Genetic mutations in genes encoding for potassium channel protein structures have been recently associated with episodes of atrial fibrillation in asymptomatic patients. The aim of this study is to investigate the ...
Arrhythmogenicity quantification of two genetic defects affecting IKr channel in AF patients

Belletti, R.; Martínez Mateu, L.; Romero Pérez, Lucia; Cherry, E.; Fenton, F. H.; Saiz Rodríguez, Francisco Javier (Sociedad Española de Ingeniería Biomédica, 2020-11-27)

[EN] Atrial fibrillation (AF) is the most common cardiac arrhythmia characterized by disorganized electrical activations of the upper chambers of the heart, leading to uncoordinated contraction and compromising the pumping ...
Atrial Fibrosis Hampers Non-invasive Localization of Atrial Ectopic Foci From Multi-Electrode Signals: A 3D Simulation Study

Godoy, Eduardo J.; Lozano, Miguel; García-Fernández, Ignacio; Ferrer-Albero, Ana; MacLeod, Rob; Saiz, Javier; Sebastián, Rafael (Frontiers Media SA, 2018-05-18)

[EN] Introduction: Focal atrial tachycardia is commonly treated by radio frequency ablation with an acceptable long-term success. Although the location of ectopic foci tends to appear in specific hot-spots, they can be ...
Atrial fibrosis identification with unipolar electrogram eigenvalue distribution analysis in multi-electrode arrays

Riccio, Jennifer; Alcaine, Alejandro; Rocher, Sara; Martínez-Mateu, Laura; Saiz Rodríguez, Francisco Javier; Invers-Rubio, Eric; Guillem Sánchez, María Salud; Martínez, Juan Pablo; Laguna, Pablo (Springer-Verlag, 2022-09-13)

[EN] Atrial fibrosis plays a key role in the initiation and progression of atrial fibrillation (AF). Atrial fibrosis is typically identified by a peak-to-peak amplitude of bipolar electrograms (b-EGMs) lower than 0.5 mV, ...
Atrial low voltage areas: A comparison between atrial fibrillation and sinus rhythm

Andrés Lahuerta, Ana; Roberto, Carlos; Saiz Rodríguez, Francisco Javier; Cano, Óscar; Martínez-Mateu, Laura; Alonso, Pau; Saurí, Assumpció; Quesada, Aurelio; Osca, Joaquín (VM Media Sp zo.o. - VMGroup SK, 2022)

[EN] Background: Atrial fibrosis can promote atrial fibrillation (AF). Electroanatomic mapping (EAM) can provide information regarding local voltage abnormalities that may be used as a surrogate marker for fibrosis. Specific ...