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Listar por autor "Gallego Ferrer, Gloria"

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A cell-free approach with a supporting biomaterial in the form of dispersed microspheres induces hyaline cartilage formation in a rabbit knee model

Zurriaga Carda, Javier; Lastra, Maria L.; Antolinos-Turpin, Carmen M.; Morales-Román, Rosa M.; Sancho-Tello, María; Perea-Ruiz, Sofía; Milián, Lara; Fernández, Juan M.; Cortizo, Ana M.; Carda, Carmen; Gallego-Ferrer, Gloria; Gómez Ribelles, José Luís (John Wiley & Sons, 2020-05)

[EN] The objective of this study was to test a regenerative medicine strategy for the regeneration of articular cartilage. This approach combines microfracture of the subchondral bone with the implant at the site of the ...
An experimental fatigue study of a porous scaffold for the regeneration of articular cartilage

Vikingsson, Line Karina Alva; Gómez-Tejedor, José Antonio; Gallego-Ferrer, Gloria; Gómez Ribelles, José Luís (Elsevier, 2015-05-01)

The aim of this experimental study is to predict the long-term mechanical behavior of a porous scaffold implanted in a cartilage defect for tissue engineering purpose. Fatigue studies were performed by up to 100,000 ...
An experimental model to mimic the mechanical behavior of a scaffold in a cartilage defect

Vikingsson, Line Karina Alva (Universitat Politècnica de València, 2015-07-29)

[EN] Abstract The main purpose of this thesis is the design and characterization of an experimental articular cartilage model. The in vitro model is composed of a macro and micro- porous Polycaprolactone scaffold with ...
An in vitro experimental model to predict the mechanical behaviour of macroporous scaffolds implanted in articular cartilage

Vikingsson, Line Karina Alva; Gallego-Ferrer, Gloria; Gómez-Tejedor, José Antonio; Gómez Ribelles, José Luís (Elsevier, 2014-04)

A model is proposed to assess mechanical behaviour of tissue engineering scaffolds and predict their performance in vivo during tissue regeneration. To simulate the growth of tissue inside the pores of the scaffold, the ...
Análisis nanomecánico de modelos de membrana celular mediante sensores acusticos de superficie de ultra-alta fecuencia

Guerrero Calatayud, Carlos (Universitat Politècnica de València, 2018-10-17)

[ES] El objetivo del proyecto es investigar sistemas lipídicos simuladores de la membrana celular mediante sensores acústicos de alta frecuencia. Estos sensores darán información acerca de las propiedades nanomecánicas y ...
ANÁLISIS Y ESTUDIO DE LA COHERENCIA DE DATOS PARA SISTEMAS ELECTROLÍTICOS CON AGUA PURA Y DISOLVENTES MIXTOS

Vaqué Aura, Santiago (Universitat Politècnica de València, 2020-07-10)

[ES] Durante los últimos años, la necesidad de mejorar los modelos termodinámicos, haciéndolos más precisos y predecibles para sistemas complejos, ha aumentado. La complejidad de los sistemas electrolíticos se debe ...
Antibacterial topographical cues on titanium surfaces to reduce infection of bone implants

Gilabert Chirivella, Eduardo (Universitat Politècnica de València, 2015-11-10)

Proyecto confidencial (Riunet)
Bioactive organic inorganic poly(CLMA-co-HEA)/silica nanocomposites

Ivashchenko, Sergiy; Escobar Ivirico, Jorge Luis; García Cruz, Dunia Mercedes; Campillo Fernández, Alberto José; Gallego-Ferrer, Gloria; Monleón Pradas, Manuel (SAGE Publications, 2015)

[EN] A series of novel poly(CLMA-co-HEA)/silica nanocomposites is synthesized from caprolactone 2-(methacryloyloxy)ethyl ester (CLMA) and 2-hydroxyethyl acrylate (HEA) as organic comonomers and the simultaneous sol-gel ...
Biointegration of corneal macroporous membranes based on poly(ethyl acrylate) copolymers in an experimental animal model

Alió del Barrio, Jorge L.; Chiesa, Massimo; Gallego-Ferrer, Gloria; Garagorri, Nerea; Briz, Nerea; Fernández Delgado, Jorge; Sancho-Tello Valls, María; Carda Botella, Carmen; García-Tuñón, Ignacio; Bataille, Laurent; Rodríguez, Alejandra; Arnalich Montiel, Francisco; Gómez Ribelles, José Luís; Antolinos Turpín, Carmen María; Gómez Tejedor, José Antonio (Wiley: 12 months, 2015-03)

Currently available keratoprosthesis models (nonbiological corneal substitutes) have a less than 75% graft survival rate at 2 years. We aimed at developing a model for keratoprosthesis based on the use of poly(ethyl acrylate) ...
Biomimetic 3D environment based on microgels as a model for the generation of drug resistance in multiple myeloma

Marín-Payá, Juan Carlos; Díaz-Benito, Blanca; Amaro Martins, Luis; Clara Trujillo, Sandra; Cordón, Lourdes; Lanceros-Méndez, Senentxu; Gallego-Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís (MDPI AG, 2021-12)

[EN] The development of three-dimensional environments to mimic the in vivo cellular response is a problem in the building of disease models. This study aimed to synthesize and validate three-dimensional support for culturing ...
Biomimetic 3D Environment Based on Microgels as a Model for the Generation of Drug Resistance in Multiple Myeloma

Marin Paya, Juan Carlos; Díaz Benito, Blanca; Amaro Martins, Luis; Clara Trujillo, Sandra; Cordón, Lourdes; Lanceros-Mendez, Senentxu; Gallego Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís (Universitat Politècnica de València, 2021-12-14)

The development of three-dimensional environments to mimic the in vivo cellular response is a problem in the building of disease models. This study aimed to synthesize and validate three-dimensional support for culturing ...
Biomimetic hydroxyapatite coating on pore walls improves osteointegration of poly(L-lactic acid) scaffolds

Deplaine, Harmony; Lebourg, Myriam Madeleine; Ripalda, P; Vidaurre Garayo, Ana Jesús; Sanz-Ramos, Patricia; Mora, Gonzalo; Prósper, Felipe; Ochoa, I.; Doblare Castellano, Manuel; Gómez Ribelles, José Luís; IZAL AZCARATE, IÑIGO; Gallego-Ferrer, Gloria (Wiley, 2013-01)

[EN] Polymer ceramic composites obtained as the result of a mineralization process hold great promise for the future of tissue engineering. Simulated body fluids (SBFs) are widely used for the mineralization of polymer ...
Biomimetic injectable hydrogels of gelatin and hyaluronic acid for hepatic cell culture

Rodríguez Fernández, Julio (Universitat Politècnica de València, 2024-09-02)

[ES] La ingeniería tisular hepática ofrece una herramienta propicia de cribado toxicológico y modelización de enfermedades, que también podría proporcionar una terapia alternativa al trasplante de hígado para tratar ...
Biomimetic microgels for articular cartilage regeneration. A minipig knee model

Milián, Lara; Ródenas Rochina, Joaquín; Alcorisa, Ignacio; Plá-Salom, Júlia; Aguilar Hernández, Ángel; Gómez-Tejedor, José-Antonio; Gallego-Ferrer, Gloria; Sancho-Tello, María; Monllau, Juan Carlos; Mata Roig, Manuel; Gómez Ribelles, José Luís (Elsevier, 2024-10-24)

[EN] The aim of this study is to explore, with an in vivo model, the regeneration of articular cartilage that can be obtained with a strategy that combines the stimulation of the subchondral bone with the implantation of ...
Biomimetic microspheres for 3D mesenchymal stem cell culture and characterization

Clara-Trujillo, Sandra; Marin-Paya, Juan Carlos; Cordón, Lourdes; Sempere, Amparo; Gallego-Ferrer, Gloria; Gómez Ribelles, José Luís (Elsevier, 2019-05-01)

[EN] Stem cells reside in niches, specialized microenvironments that sustain and regulate their fate. Extracellular matrix (ECM), paracrine factors or other cells are key niche regulating elements. As the conventional 2D ...
Bone-Mimicking Injectable Gelatine/Hydroxyapatite Hydrogels

Rogina, A.; Sandrk, N; Teruel Biosca, Laura; Antunovic, M.; Ivankovic, M.; Gallego-Ferrer, Gloria (Croatian Society of Chemical Engineers/HDKI, 2019)

[EN] Bioactive synthetic hydrogels have emerged as promising materials because they can provide molecularly tailored biofunctions and adjustable mechanical properties. To mimic the mineralogical and organic components of ...
Borax-loaded injectable alginate hydrogels promote muscle regeneration in vivo after an injury

Ciriza, Jesús; Rodriguez-Romano, Ana; Nogueroles, Ignacio; Gallego-Ferrer, Gloria; Martín Cabezuelo, Rubén; Pedraz, José Luis; Rico Tortosa, Patricia María (Elsevier BV, 2021-04)

[EN] Muscle tissue possess an innate regenerative potential that involves an extremely complicated and synchronized process on which resident muscle stem cells play a major role: activate after an injury, differentiate and ...
Capacitively Coupled Electrical Stimulation of Rat Chondroepiphysis Explants: A Histomorphometric Analysis

Vaca-González, J. J.; Escobar, J.F.; Guevara, J.M.; Hata, Y. A.; Gallego-Ferrer, Gloria; Garzón-Alvarado, D. A. (Elsevier, 2019-04)

[EN] The growth plate is a cartilaginous layer present from the gestation period until the end of puberty where it ossifies joining diaphysis and epiphysis. During this period several endocrine, autocrine, and paracrine ...
Caracterización de la morfología y la interacción con el agua de hidrogeles inyectables de gelatina y ácido hialurónico para ingeniería tisular

Culebras Martínez, María (Universitat Politècnica de València, 2017-09-14)

[EN] Recent advances in tissue engineering have led to the development of polymer scaffolds with suitable characteristics and properties capable of mimicking natural tissue and fulfilling the different functions that the ...
Caracterización de una plataforma electroactiva de hidrogel-microesferas para la diferenciación osteogénica de células madre mesenquimales

García Briega, María Inmaculada (Universitat Politècnica de València, 2020-07-15)

[ES] El hueso es un tejido muy heterogéneo, por lo que crear una plataforma de cultivo que imite su entorno es un gran desafío. El hueso es un tejido piezoeléctrico y esta propiedad la producen las fibras de colágeno que ...