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A novel role for protein kinase Gcn2 in yeast tolerance to intracellular acid stress

Hueso Lorente, Guillem; Aparicio Sanchis, Rafael; Montesinos De Lago, Consuelo; Lorenz, Silvia; Murguía Ibáñez, José Ramón; Serrano Salom, Ramón (Portland Press, 2012)

Intracellular pH conditions many cellular systems, but its mechanisms of regulation and perception are mostly unknown. We have identified two yeast genes important for tolerance to intracellular acidification caused by ...
Genetic alterations leading to increases in internal potassium concentrations are detrimental for DNA integrity in Saccharomyces cerevisiae

Merchan, Stéphanie Emilie; Pedelini, Leda; Hueso Lorente, Guillem; Calzada, Arturo; Serrano Salom, Ramón; Yenush, Lynne (Wiley, 2011-02)

[EN] We have investigated the effects of alterations in potassium homeostasis on cell cycle progression and genome stability in Saccharomyces cerevisiae. Yeast strains lacking the PPZ1 and PPZ2 phosphatase genes, which ...
Mecanismos de regulación de transportadores de membrana. Interacción entre AMPK y Nedd4.2

Hueso Lorente, Guillem (Universitat Politècnica de València, 2012-01-27)

La regulación del transporte iónico es importante en mamíferos ya que disfunciones en él producen enfermedades cardiovasculares, neurodegenerativas, etc. En este contexto, se ha descrito que mutaciones en el gen que codifica ...

Mostrando ítems 1-3 de 3