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Listar por autor "Jiménez Molero, María Consuelo"

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A combined photophysical and computational study on the binding of mycophenolate mofetil and its major metabolite to transport proteins

Vendrell-Criado, Victoria; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo (Elsevier, 2018-06-15)

[EN] Binding of the inmunodrepresive agent mycophenolate mofetil (MMP) and its pharmacologically active metabolite mycophenolic acid (MPA) to human serum albumin (HSA) and ¿1-acid glycoprotein (HAAG) has been investigated ...
A joint experimental/theoretical study of the ultrafast excited state deactivation of deoxyadenosine and 9-methyladenine in water and acetonitrile

Gustavsson, Thomas; Sarkar, Nilmoni; Vayá Pérez, Ignacio; Jiménez Molero, María Consuelo; Markovitsi, Dimitra; Improta, Roberto (Royal Society of Chemistry, 2013)

The excited states of deoxyadenosine (dA) and 9-methyladenine (9Me-Ade) were studied in water and acetonitrile by a combination of steady-state and time-resolved spectroscopy and quantum chemical calculations. Femtosecond ...
A New Pathway for Protein Haptenation by beta-Lactams

Pérez-Ruiz, Raúl; Lence, Emilio; Andreu Ros, María Inmaculada; Limones Herrero, Daniel; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo (John Wiley & Sons, 2017-10-09)

[EN] The covalent binding of beta-lactams to proteins upon photochemical activation has been demonstrated by using an integrated approach that combines photochemical, proteomic and computational studies, selecting human ...
Accessible Low-Cost Laser Pointers for the Reduction of Aryl Halides via Triplet-Triplet Annihilation Upconversion in Aerated Gels

Domínguez Domínguez, Paola; Bonardd, Sebastian; Martín Koury, Samuel; Pérez-Ruiz, Raúl; Jiménez Molero, María Consuelo; Díaz Díaz, David (MDPI, 2022-12)

[EN] The search for economic alternatives in the use of expensive scientific equipment represents a way of providing many laboratories access to scientific developments that, otherwise, might be hampered by economic ...
Aerobic Visible-Light-Driven Borylation of Heteroarenes in a Gel Nanoreactor

Herrera-Luna, Jorge Carlos; Díaz Díaz, David; Abramov, Alex; Encinas Perea, Susana; Jiménez Molero, María Consuelo; Pérez-Ruiz, Raúl (American Chemical Society, 2021-03-19)

[EN] Heteroarene boronate esters constitute valuable intermediates in modern organic synthesis. As building blocks, they can be further applied to the synthesis of new materials, since they can be easily transformed into ...
ANALYTICAL METHOD VALIDATION FOR THE QUANTIFICATION OF BRODIFACOUM IN THE TEST ITEM I-BITE, BLOCK BAIT (BRODIFACOUM 0.0025% W/W A.1.)

Saiz Rubio, Ana (Universitat Politècnica de València, 2023-10-10)

[EN] The purpose of the study is the validation of a HPLC-DAD method for identifying and quantifying Brodifacoum in a pure standard sample according to SANCO/3030/99 guideline. Brodifacoum is an anticoagulant that reduces ...
Arylisoquinoline-derived organoboron dyes with a triaryl skeleton show dual fluorescence

Pais, Vania F.; Neumann, T.; Vayá Pérez, Ignacio; Jiménez Molero, María Consuelo; Ros, Abel; Pischel, Uwe (Beilstein-Institut, 2019-11-04)

[EN] Four new dyes that derive from borylated arylisoquinolines were prepared, containing a third aryl residue (naphthyl, 4-methoxynaphthyl, pyrenyl or anthryl) that is linked via an additional stereogenic axis. The triaryl ...
Bypassing the energy barrier of homolytic photodehalogenation in chloroaromatics through self-quenching

Limones Herrero, Daniel; Pérez Ruiz, Raul; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2013)

Reductive photodehalogenation of chloroaromatics is assumed to proceed from the triplet excited state, although its energy is often insufficient to promote a clean homolytic C¿Cl cleavage. A clear-cut experimental proof ...
Catálisis redox mediante conversión fotónica a alta frecuencia

Castellanos Soriano, Jorge (Universitat Politècnica de València, 2024-03-25)

[ES] La conversión fotónica a alta frecuencia basada en la aniquilación triplete-triplete (CA-ATT) es considerada una de las tecnologías más atractivas para convertir radiación de longitud de onda de menor energía en otra ...
Characterization of the lowest singlet and triplet states of S-Flurbiprofen

Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel; Tormos Faus, Rosa Esperanza; Vayá Pérez, Ignacio (The Royal Society of Chemistry, 2004)

[EN] The photophysical properties of S-flurbiprofen [S-2-fluoro-alpha-methyl-4-biphenylacetic acid], a nonsteroidal anti-inflammatory drug, have been examined using steady-state and time-resolved spectroscopic techniques. ...
Cycloreversion of beta-lactams via photoinduced electron transfer

Pérez Ruiz, Raul; Sáez Cases, José Antonio; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (Royal Society of Chemistry, 2014-11-14)

The radical anions of beta-lactams, photogenerated in the presence of DABCO as an electron donor, undergo cycloreversion via N-C4 bond cleavage, back electron transfer and final C2-C3 bond cleavage, leading to olefins. The ...
Degradation of N-methyl 2-pyrrolidone trough advanced oxidation process in presence of Bismuth-based heterogenous catalysts

Molina García, Miquel (Universitat Politècnica de València, 2022-07-19)

[EN] This study investigates the degradation of N-methyl-2-pyrrolidone (NMP) by UV-C and UV-C/PMS-treatment processes. The degradation of NMP was less than 2% by UV-C photolysis. To enhance the degradation of NMP, zinc and ...
Determination of enantiomeric compositions by transient absorption spectroscopy using proteins as chiral selectors

Vayá Pérez, Ignacio; Bueno Alejo, Carlos Javier; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (John Wiley & Sons, 2008)
Developing new approaches on recycling of plastic waste using green solvents

López Mejías, Dulce Milagro (Universitat Politècnica de València, 2023-10-11)

[ES] El polietileno tereftalato (PET) es un poliéster termoplástico que suele utilizarse para envases. El 12% de los residuos sólidos mundiales por volumen están compuestos de PET. A lo largo de los años se ha desarrollado ...
Diastereodifferentiation of novel naphthalene dyads by fluorescence quenching and excimer formation

Abad Fuentes, Sergio; Vayá Pérez, Ignacio; Jiménez Molero, María Consuelo; Pischel ., Uwe; Miranda Alonso, Miguel Ángel (John Wiley & Sons, 2006)

[EN] Four new bichromophoric naphthalene dyads in form of diastereomeric pairs are synthesized and photophysically characterized. For a closely related group of compounds (NAP-NAP MNAP-NAP, MNAP-MNAP), systematic variation ...
Diseño de nanopartículas de oro funcionalizadas con AINEs y proteínas para su uso en biomedicina

Tamarit Mayo, Lorena (Universitat Politècnica de València, 2018-10-11)

[ES] En este trabajo se han diseñado una serie de nanopartículas de oro (AuNPs) esféricas funcionalizadas con fármacos (antiinflamatorios no esteroideos, AINEs) con la finalidad de realizar un estudio fotofísico completo ...
Diseño de nanorods de oro con fármacos fotoactivos para estudios de citotoxicidad celular

Palomares Ferrando, Adrià (Universitat Politècnica de València, 2021-10-06)

[ES] Este proyecto se ha centrado en el diseño y estudio de las propiedades de nanorods de oro para su posible aplicación en terapia fototérmica (PTT), para el tratamiento de ciertos tipos de cánceres. La terapia fototérmica ...
Drug-drug interactions within protein cavities probed by triplet-triplet energy transfer

Nuin Plá, Neus Edurne; Jiménez Molero, María Consuelo; Sastre Navarro, German Ignacio; Andreu Ros, María Inmaculada; Miranda Alonso, Miguel Ángel (American Chemical Society, 2013-05-16)

A new direct and noninvasive methodology based on transient absorption spectroscopy has been developed to probe the feasibility of drug-drug interactions within a common protein binding site. The simultaneous presence of ...
Drug/protein interactions studied by time-resolved fluorescence spectroscopy

Gustavsson, Thomas; Markovitsi, Dimitra; Vayá Pérez, Ignacio; Bonancía Roca, Paula; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (Society of Photo-optical Instrumentation Engineers (SPIE), 2014)

[EN] We report here on a recent time-resolved fluorescence study [1] of the interaction between flurbiprofen (FBP), a chiral non-steroidal anti-inflammatory drug, and human serum albumin (HSA), the main transport protein ...
Economic analysis of fungal pretreatment for bioethanol production

Moreno Sánchez, Luis David (Universitat Politècnica de València, 2022-09-14)

[ES] El trabajo consiste en el cálculo de las materias primas, uso de energía de una planta de obtención de bioetanol que utiliza un pretratamiento fúngico que consiste en un proceso de esterilización del aserrín de álamo ...