Vayá Pérez, Ignacio; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2007)
[EN] Fluorescence and laser-flash photolysis measurements have been performed on two pairs of diastereomeric dyads that contain the nonsteroidal anti-inflammatory drug (S)- or (R)-flurbiprofen (FBP) and (S)-tryptophan ...
Bonancía Roca, Paula; Vayá Pérez, Ignacio; Climent Olmedo, María José; Gustavsson, Thomas; Markovitsi, Dimitra; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2012-09-06)
Excited-state interactions between (S)- or (R) fluorescence (S)- or (R)-FBP) and thymidine (dThd) covalently linked in dyads 1 or 2 have been investigated. In both dyads, the only emitting species is (FBP)-F-1*, but with ...
Pérez Ruiz, Raul; Domingo, Luis R; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2011)
[EN] The feasibility of an electron transfer imino-Diels Alder reaction betweenN-benzylideneaniline and arylalkenes in the presence of a pyrylium salt
as a photosensitizer has been demonstrated by a combination of product ...
Lineros-Rosa, Mauricio; Francés-Monerris, Antonio; Monari, Antonio; Miranda Alonso, Miguel Ángel; Lhiaubet, Virginie Lyria(The Royal Society of Chemistry, 2020-11-28)
[EN] Interaction of nucleic acids with light is a scientific question of paramount relevance not only in the understanding of life functioning and evolution, but also in the insurgence of diseases such as malignant skin ...
Fraga-Timiraos, Ana Belén; Francés-Monerris, Antonio; Rodríguez Muñiz, Gemma María; Navarrete-Miguel, Miriam; Miranda Alonso, Miguel Ángel; Roca Sanjuan, Daniel; Lhiaubet, Virginie Lyria(John Wiley & Sons, 2018-10-12)
[EN] Azetidines are interesting compounds in medicine and chemistry as bioactive scaffolds and synthetic intermediates. However, photochemical processes involved in the generation and fate of azetidine-derived radical ions ...
Mayorga, Cristobalina; Andreu Ros, María Inmaculada; Aranda, Ana; Doña, Inmaculada; Montañez, M. Isabel; Blanca-López, Natalia; Ariza, Adriana; Nuin Plá, Neus Edurne; Blanca, Miguel; Miranda Alonso, Miguel Ángel; Torres, Mª José(Karger, 2013)
Fluoroquinolones (FQs) are photoreactive drugs, but it is not known whether laboratory light exposure can influence the induction of photoproducts and modify in vitro test results. The basophil activation test (BAT) has ...
Vendrell Criado, Victoria(Universitat Politècnica de València, 2015-12-09)
[EN] UV radiation is able to induce changes in the chemical composition of DNA that have been closely related to skin cancer. Among the most relevant lesions, damage to pyrimidine bases leading to bipyrimidine units ...
Limones Herrero, Daniel(Universitat Politècnica de València, 2016-01-07)
[EN] The use of biomimetic media such as serum albumins (SAs), a1-acid glycloproteins (AAGs), cyclodextrins (CDs) and sodium dodecyl sulfate (SDS) micelles is combined with photophysical techniques (fluorescence (F) and ...
Durán Giner, Eva de Les Neus(Universitat Politècnica de València, 2017-07-03)
The general aim of the present thesis is to undertake a thorough photochemical study on a family of aromatic N-oxides. Specifically, the selected compounds are 4-desoxytirapazamine (DTPZ) and 4-nitroquinoline N-oxide (NQNO), ...
Martínez, Carmen; Andreu Ros, María Inmaculada; Amo, Gemma; Miranda Alonso, Miguel Ángel; Esguevillas, Gara; Torres, María José; Blanca López, Natalia; Blanca, Miguel; Garcia Martin, Elena; Agúndez, José A.G.(Elsevier, 2014-12-01)
Metamizole is a pain-killer drug that has been banned in some countries because of its toxicity, but it is still used in many countries due to its effective analgesic and antispasmodic properties. Although large variability ...
Nardi, Giacomo; Marín García, Mª Luisa; de Souza, Pierre A.; Lhiaubet, Virginie Lyria; Miranda Alonso, Miguel Ángel(The Royal Society of Chemistry, 2014)
[EN] The photochemical properties of itraconazole (1), a broad-spectrum antifungal agent, have been investigated in connection with reported skin photosensitivity disorders. Steady state photolysis, fluorescence and ...
Miró, Paula; Gomez-Mendoza, Miguel; SASTRE NAVARRO, GERMAN IGNACIO; Cuquerella Alabort, Maria Consuelo; Miranda Alonso, Miguel Ángel; Marín García, Mª Luisa(John Wiley & Sons, 2019-05-17)
[EN] Benzophenone (BP) and drugs containing the BP chromophore, such as the non-steroidal anti-inflammatory drug ketoprofen, have been widely reported as DNA photo-sensitizers through triplet-triplet energy transfer (TTET). ...
Pérez Ruiz, Raul; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2014-04)
[EN] Discovered more than eight decades ago, the Diels-Alder (DA) cycloaddition (CA) remains one of the most versatile tools in synthetic organic chemistry. Hetero-DA processes are powerful methods for the synthesis of ...
Palumbo, Fabrizio; Andreu Ros, María Inmaculada; Brunetti, M.; Schmallegger, Max; Gescheidt, Georg; Neshchadin, Dmytro; Miranda Alonso, Miguel Ángel(American Chemical Society, 2019-12-06)
[EN] Cholesterol (Ch) is an integral part of cell membrane, where it is prone to oxidation. In humans, oxidation of Ch is commonly linked to various pathologies like Alzheimer's disease, atherosclerosis, and even cancer, ...
Miró Richart, Paula(Universitat Politècnica de València, 2016-05-16)
[EN] Bile acids are a family of amphiphilic steroids that play a pivotal role in physiological functions such as elimination of cholesterol or solubilization of lipids. Chemically, they share a steroidal skeleton with an ...
Rodríguez Muñiz, Gemma María; Gomis Vicens, Juan; Arques Sanz, Antonio; Amat Payá, Ana María; Marín García, Mª Luisa; Miranda Alonso, Miguel Ángel(Wiley-Blackwell, 2014-11)
In this work, a kinetic model, in combination with time-resolved experiments, is applied to assess the involvement of OH in the photodegradation of emerging pollutants (EPs) by means of advanced oxidation processes. In ...
Molins-Molina, Oscar; Lence, Emilio; Limones-Herrero, Daniel; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo(Royal Society of Chemistry, 2019-01-07)
[EN] The non-steroidal anti-inflammatory drug (S)-carprofen (CPF) has been used as a photoactive probe to investigate the possible existence of a common recognition center in serum albumins (SAs) of different species. The ...
Blanca-López, Natalia; Pérez-Alzate, D.; Andreu Ros, María Inmaculada; Doña, Inmaculada; Agundez, Javier A.; García-Martín, Elena; Salas, M.; Miranda Alonso, Miguel Ángel; Torres, M. J.; Cornejo-Garcia, J.A.; Blanca, M.; Canto, G.(Wiley, 2016-07)
[EN] Background: Although ibuprofen and other arylpropionic acid derivatives (APs)
are the most common medicines involved in hypersensitivity drug reactions
(HDRs) to NSAIDs, no patient series studies have been performed ...
Khramtsova, E.A.; Sosnovsky, D.V.; Ageeva, A.A.; Nuin Plá, Neus Edurne; Marín García, Mª Luisa; Purtov, P.A.; Borisevich, S.S.; Khursan, S.L.; Roth, H.D.; Miranda Alonso, Miguel Ángel; Plyusnin, V.F.; Leshina, T.V.(Royal Society of Chemistry, 2016-05-14)
[EN] The model reaction of photoinduced donor-acceptor interaction in linked systems (dyads) has been used to study the comparative reactivity of a well-known anti-inflammatory drug, (S)-naproxen (NPX) and its (R)-isomer. ...