Gustavsson, Thomas; Sarkar, Nilmoni; Vayá Pérez, Ignacio; Jiménez Molero, María Consuelo; Markovitsi, Dimitra; Improta, Roberto(Royal Society of Chemistry, 2013)
The excited states of deoxyadenosine (dA) and 9-methyladenine (9Me-Ade) were studied in water and
acetonitrile by a combination of steady-state and time-resolved spectroscopy and quantum chemical
calculations. Femtosecond ...
[EN] The photochemical properties of the DNA duplex (dA)(20) center dot (dT)(20) are compared with those of the parent single strands. It is shown that base pairing increases the probability of absorbing UVA photons, ...
Gustavsson, Thomas; Markovitsi, Dimitra; Vayá Pérez, Ignacio; Bonancía Roca, Paula; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(Society of Photo-optical Instrumentation Engineers (SPIE), 2014)
[EN] We report here on a recent time-resolved fluorescence study [1] of the interaction between flurbiprofen (FBP), a chiral non-steroidal anti-inflammatory drug, and human serum albumin (HSA), the main transport protein ...
[EN] Transfer of the electronic excitation energy in calf thymus DNA is studied by time-resolved fluorescence spectroscopy. The fluorescence anisotropy, after an initial decay starting on the femtosecond time scale, dwindles ...
[EN] The study addresses interconnected issues related to two major types of cycloadditions between adjacent thymines in DNA leading to cyclobutane dimers (T <> Ts) and (6-4) adducts. Experimental results are obtained for ...
Vayá Pérez, Ignacio; Bonancía Roca, Paula; Jiménez Molero, María Consuelo; Markovitsi, Dimitra; Gustavsson, Thomas; Miranda Alonso, Miguel Ángel(Royal Society of Chemistry, 2013)
We report here on the interaction dynamics between flurbiprofen (FBP) and tryptophan (Trp) covalently linked in model dyads and in a complex of FBP with human serum albumin (HSA) probed by time-resolved fluorescence ...
Bonancía Roca, Paula; Vayá Pérez, Ignacio; Climent Olmedo, María José; Gustavsson, Thomas; Markovitsi, Dimitra; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2012-09-06)
Excited-state interactions between (S)- or (R) fluorescence (S)- or (R)-FBP) and thymidine (dThd) covalently linked in dyads 1 or 2 have been investigated. In both dyads, the only emitting species is (FBP)-F-1*, but with ...
[EN] The publication deals with polymeric pA·pT and oligomeric A(20)·T(20) DNA duplexes whose fluorescence is studied by time-correlated single photon counting. It is shown that their emission on the nanosecond timescale ...
Vayá Pérez, Ignacio; Gustavsson, Thomas; Markovitsi, Dimitra; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo(Elsevier, 2016-05-15)
[EN] The photoreactivity of diastereomeric dyads containing (S)- or (R)-flurbiprofen (FBP) and (S)-Tyr, either directly linked (1) or separated by a cyclic spacer (3) has been investigated. The main feature is a remarkable ...
Bonancía Roca, Paula; Vayá Pérez, Ignacio; Markovitsi, Dimitra; Gustavsson, Thomas; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(Royal Society of Chemistry, 2013)
The photochemical processes occurring in diastereomeric dyads (S, S)-1 and (S, R)-1, prepared by conjugation of (S)-2-(2-hydroxy-1,1'-biphenyl-4-yl) propanoic acid ((S)-BPOH) with (S)- and (R)-Trp, have been investigated. ...