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Listar por autor "Rico Tortosa, Patricia María"

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Assessment of parameters influencing fiber characteristics of electrospun Poly(ethyl methacrylate) scaffolds

Gómez-Tejedor, José Antonio; Van Overberghe, Niek; Rico Tortosa, Patricia María; Gómez Ribelles, José Luís (Elsevier, 2011)

This work evaluates the influence of electrospinning process parameters on the mean diameter and standard deviation of fiber diameters in electrospun poly(ethyl methacrylate) (PEMA). Processing conditions were selected ...
Borax induces osteogenesis by stimulating NaBC1 transporter via activation of BMP pathway

Rico Tortosa, Patricia María; Rodrigo Navarro, Aleixandre; Sánchez-Pérez, Laura; Salmerón Sánchez, Manuel (Springer Nature, 2020-11-27)

[EN] The intrinsic properties of mesenchymal stem cells (MSCs) make them ideal candidates for tissue engineering applications. Efforts have been made to control MSC behavior by using material systems to engineer synthetic ...
Borax-loaded injectable alginate hydrogels promote muscle regeneration in vivo after an injury

Ciriza, Jesús; Rodriguez-Romano, Ana; Nogueroles, Ignacio; Gallego-Ferrer, Gloria; Martín Cabezuelo, Rubén; Pedraz, José Luis; Rico Tortosa, Patricia María (Elsevier BV, 2021-04)

[EN] Muscle tissue possess an innate regenerative potential that involves an extremely complicated and synchronized process on which resident muscle stem cells play a major role: activate after an injury, differentiate and ...
Chondrocytes cultured in an adhesive macroporous scaffold subjected to stirred flow bioreactor behave like in static culture

Gamboa Martínez, Tatiana Carolina; Ródenas Rochina, Joaquín; Rico Tortosa, Patricia María; Lebourg, Myriam Madeleine; Gómez Ribelles, José Luís; Salmerón Sánchez, Manuel; Gallego-Ferrer, Gloria (American Scientific Publishers, 2013)

[EN] The aim of this study was to evaluate whether mechanical stimulation helps to modulate the redifferentiation of human chondrocytes on adhesive 3D substrates. In a previous work, it was shown that chondrocytes seeded ...
Controlled Assembly of Fibronectin Nanofibrils Triggered by Random Copolymer Chemistry

MNATSAKANYAN, HAYK; Rico Tortosa, Patricia María; Grigoriou, Eleni; Maturana Candelas, Aarón; Rodrigo Navarro, Aleixandre; Salmerón Sánchez, Manuel; Sabater i Serra, Roser (American Chemical Society, 2015-08-19)

Fibronectin fibrillogenesis is the physiological process by which cells elaborate a fibrous FN matrix. Poly(ethyl acrylate), PEA, has been described to induce a similar process upon simple adsorption of fibronectin (FN) ...
Controlled wettability, same chemistry: biological activity of plasma-polymerized coatings

Cantini, Marco; Rico Tortosa, Patricia María; Moratal Pérez, David; Salmerón Sánchez, Manuel (Royal Society of Chemistry, 2012)

Plasma polymerization was used to produce novel nanometric coatings able to direct fibronectin adsorption and cell response. Using ethyl acrylate as a monomer, we obtain coatings whose chemical composition maintains some ...
Desarrollo de nano fibras materiales realizadas mediante electrohilado coaxial cargadas con iones bioactivos para aplicaciones en regeneración del tejido muscular

Martínez Gómez-Aldaraví, Adrián (Universitat Politècnica de València, 2016-10-18)

[ES] En este trabajo se plantea el diseño de una membrana electrohilada capaz de actuar como medio de liberación controlada de iones Boro con aplicaciones en Ingeniería Tisular para la regeneración/reparación de músculo. ...
Determination of synergistic effect between roughness and surface chemistry on cell adhesion of a multilayer Si- Hydroxyapatite coating on Ti6Al4V obtained by magnetron sputtering

Pérez Zapata, K.; Lenis, J.A.; Rico Tortosa, Patricia María; Gómez Ribelles, José Luís; Bolívar, F.J. (Elsevier, 2022-10-31)

[EN] Ti alloys are widely used in the biomedical field because they have an adequate balance between mechanical properties, corrosion resistance and biocompatibility. However, when this material is incorporated in the human ...
Development of a Ta/TaN/TaNx(Ag)y/TaN nanocomposite coating system and bio-response study for biomedical applications

Echavarria, Aida M.; Rico Tortosa, Patricia María; Gómez Ribelles, José Luís; Pacha-Olivenza, Miguel A.; Fernandez-Calderon, Maria-Coronada; Bejarano-G, Gilberto (Elsevier, 2017)

[EN] TaN(Ag) composited coatings are being investigated to improve biocompatibility of different biomedical devices due to the mechanical and chemical stability of TaN and bactericidal effect of silver nanoparticles. ...
Development of multilayer Hydroxyapatite - Ag/TiN-Ti coatings deposited by radio frequency magnetron sputtering with potential application in the biomedical field

Lenis, J.A.; Bejarano, G.; Rico Tortosa, Patricia María; Gómez Ribelles, José Luís; Bolívar, F.J. (Elsevier, 2019-11-15)

[EN] The use of composite coatings is emerging as a great alternative to conventional coatings, allowing the combination of different superficial properties that are widely desired in surgical implants, such as osteointegration ...
Dorsal and Ventral Stimuli in Cell-Material Interactions: Effecton Cell Morphology

Ballester Beltrán, José; Lebourg, Myriam Madeleine; Rico Tortosa, Patricia María; Salmerón Sánchez, Manuel (American Vacuum Society, 2012-06)

Cells behave differently between bidimensional (2D) and tridimensional (3D) environments. While most of the in vitro cultures are 2D, most of the in vivo extracellular matrices are 3D, which encourages the development of ...
Effect of boron on the differentiation of mesenchymal stem cells

Gutiérrez Salazar, Mónica Victoria (Universitat Politècnica de València, 2016-10-17)

[EN] Boron is an essential microelement in the metabolism of living organisms. However, its role is not yet well defined. It has been shown recently that boron has a positive effect on the differentiation on murine myoblasts ...
Effect of in situ formed hydroxyapatite on microstructure of freeze-gelled chitosan-based biocomposite scaffolds

Rogina, Anamarija; Rico Tortosa, Patricia María; Gallego-Ferrer, Gloria; Ivankovic, Marica; Ivankovic, Hrvoje (Elsevier, 2015-07)

New in situ highly-porous chitosan/hydroxyapatite (CS/HA) biocomposite scaffolds have been prepared via freeze-gelation technique. Different content of in situ synthesized hydroxyapatite within chitosan solution was obtained ...
Effect of topological cues on material-driven fibronectinfibrillogenesis and cell differentiation

Ballester Beltrán, José; Cantini, Marco; Lebourg, Myriam Madeleine; Rico Tortosa, Patricia María; Moratal Pérez, David; García, Andrés J.; Salmerón Sánchez, Manuel (Springer Verlag (Germany), 2012-01)

[EN] Fibronectin (FN) assembles into fibrillar networks by cells through an integrin-dependent mechanism. We have recently shown that simple FN adsorption onto poly(ethyl acrylate) surfaces (PEA), but not control polymer ...
Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors

Trujillo-Muñoz, Sara; González-García, Cristina; Rico Tortosa, Patricia María; Reid, Andrew; Windmill, James; Dalby, Matthew J.; Salmerón Sánchez, Manuel (Elsevier, 2020-09)

[EN] Extracellular matrix (ECM)-derived matrices such as Matrigel are used to culture numerous cell types in vitro as they recapitulate ECM properties that support cell growth, organisation, migration and differentiation. ...
Estudio de sistemas biomateriales basados en (micro/nano) partículas para la liberación de iones.

Bengoetxea González, Guillermo (Universitat Politècnica de València, 2021-01-26)

[ES] En este trabajo se recogen la información sobre sistemas de biomateriales basados en partículas (micro/nano) para la liberación de iones y sus posibles aplicaciones en el ámbito biosanitario. Las nanopartículas y ...
Estudio del efecto del boro y su transportador en células de cáncer de colon

Talamanca Buitrago, Blanca (Universitat Politècnica de València, 2022-09-07)

[ES] El cáncer de colon es la neoplasia maligna más frecuente que se puede presentar en el tubo digestivo y, a pesar de la incesante investigación, una de las patologías con mayor prevalencia en la población mundial. El ...
Fibronectin distribution on demixed nanoscale topographies

Perez Garnes, Manuel; González García, Cristina; Moratal Pérez, David; Rico Tortosa, Patricia María; Salmerón Sánchez, Manuel (Wichtig Editore, 2011-02-04)

[EN] Purpose: It is known that surface nanotopography influences cell adhesion and differentiation. Our aim is to analyze the effect of nanoscale topography on fibronectin adsorption and, afterwards, on cell adhesion in ...
Functional living biointerfaces to direct cell-material interaction

Rodrigo Navarro, Aleixandre (Universitat Politècnica de València, 2015-06-10)

[EN] This thesis deals with the development of a living biointerface between synthetic substrates and living cells to engineer cell-material interactions for tissue engineering purposes. This living biointerface is made ...
Functional Living Biointerphases

Saadeddin Saadeddin, Anas; Rodrigo Navarro, Aleixandre; Monedero, Vicente; Rico Tortosa, Patricia María; Moratal Pérez, David; González-Martín, María Luisa; Navarro, David; García, Andrés J.; Salmerón Sánchez, Manuel (Wiley, 2013-09)

Lactococcus lactis is modified to express a fibronectin fragment (FNIII₇₋₁₀) as a membrane protein. This interphase, based on a living system, can be further exploited to provide spatio-temporal ...