Buscar en RiuNet

Listar

Todo RiuNet

Mi cuenta

Acceder

Ayuda RiuNet

Admin. UPV

Listar por autor "Rodrigo Tarrega, Guillermo"

Mostrando ítems 1-20 de 34

Página siguiente

A binary interaction map between turnip mosaic virus and Arabidopsis thaliana proteomes

Martínez, Fernando; Carrasco, José L.; Toft, Christina; Hillung, Julia; Giménez-Santamarina, Silvia; Yenush, Lynne; Rodrigo Tarrega, Guillermo; ELENA FITO, SANTIAGO FCO (Springer Nature, 2023-01-11)

[EN] Viruses are obligate intracellular parasites that have co-evolved with their hosts to establish an intricate network of protein-protein interactions. Here, we followed a high-throughput yeast two-hybrid screening to ...
A meta-analysis reveals the commonalities and differences in Arabidopsis thaliana response to different viral pathogens

Rodrigo Tarrega, Guillermo; Carrera Montesinos, Javier; Ruiz-Ferrer, Virginia; Del Toro, F.J.; Llave, C; Voinnet, O.; Elena Fito, Santiago Fco (Public Library of Science, 2012-07)

Understanding the mechanisms by which plants trigger host defenses in response to viruses has been a challenging problem owing to the multiplicity of factors and complexity of interactions involved. The advent of genomic ...
A variant-dependent molecular clock with anomalous diffusion models SARS-CoV-2 evolution in humans

Goiriz, Lucas; Ruiz, Raúl; Garibo-i-Orts, Óscar; Conejero, J. Alberto; Rodrigo Tarrega, Guillermo (Proceedings of the National Academy of Sciences, 2023-07-25)

[EN] The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans has been monitored at an unprecedented level due to the public health crisis, yet the stochastic dynamics underlying such a process ...
Análisis y diseño de circuitos genéticos sintéticos para aplicaciones energéticas y para la participación del equipo valenciano en la competición "International Genetically Engineered Machine" organizada por el Massachusetts Institute of Technology

Rodrigo Tarrega, Guillermo (Universitat Politècnica de València, 2014-04-08)

Proyecto Confidencial
Automated sequence design of nucleic acid hybridization reactions for microRNA detection

Goiriz Beltrán, Lucas (Universitat Politècnica de València, 2019-09-05)

[EN] microRNA (miRNA) can be found in a variety of biological samples and then they represent important molecular markers for early diagnostic strategies. This work (TFG) explores a novel approach based on nested ...
Boolean Computation in Plants Using Post-translational Genetic Control and a Visual Output Signal

Cordero-Cucart, María Teresa; Rosado, A.; Majer, Eszter; Jaramillo Rosales, Alfonso; Rodrigo Tarrega, Guillermo; Daros Arnau, Jose Antonio (American Chemical Society, 2018-10)

[EN] Due to autotrophic growing capacity and extremely rich secondary metabolism, plants should be preferred targets of synthetic biology. However, developments in plants usually run below those in other taxonomic groups. ...
Computational design and designability of gene regulatory networks

Rodrigo Tarrega, Guillermo (Universitat Politècnica de València, 2011-12-30)

Nuestro conocimiento de las interacciones moleculares nos ha conducido hoy hacia una perspectiva ingenieril, donde diseños e implementaciones de sistemas artificiales de regulación intentan proporcionar instrucciones ...
CRISPR-Cas12a-Based Detection of SARS-CoV-2 Harboring the E484K Mutation

Marqués, María-Carmen; Ruiz, Raúl; Montagud-Martínez, Roser; Márquez-Costa, Rosa; Albert, Sandra; Domingo-Calap, Pilar; Rodrigo Tarrega, Guillermo (American Chemical Society, 2021-12-17)

[EN] The novel respiratory virus SARS-CoV-2 is rapidly evolving across the world with the potential of increasing its transmission and the induced disease. Here, we applied the CRISPR-Cas12a system to detect, without ...
CRISPR-Mediated Strand Displacement Logic Circuits with Toehold-Free DNA

Montagud-Martínez, Roser; Heras-Hernández, María; Goiriz, Lucas; Rodrigo Tarrega, Guillermo; Daròs, José-Antonio (American Chemical Society, 2021-05-21)

[EN] DNA nanotechnology, and DNA computing in particular, has grown extensively over the past decade to end with a variety of functional stable structures and dynamic circuits. However, the use as designer elements of ...
Describing the structural robustness landscape of bacterial small RNAs

Rodrigo Tarrega, Guillermo; Fares Riaño, Mario Ali (BioMed Central, 2012-04-13)

Background: The potential role of RNA molecules as gene expression regulators has led to a new perspective on the intracellular control and genome organization. Because secondary structures are crucial for their regulatory ...
Diagnostics of Infections Produced by the Plant Viruses TMV, TEV, and PVX with CRISPR-Cas12 and CRISPR-Cas13

Marqués, María-Carmen; Sánchez-Vicente, Javier; Ruiz, Raúl; Montagud-Martínez, Roser; Márquez-Costa, Rosa; Gómez, Gustavo; CARBONELL, ALBERTO; Daròs, José-Antonio; Rodrigo Tarrega, Guillermo (American Chemical Society, 2022-07-15)

[EN] Viral infections in plants threaten food security. Thus, simple and effective methods for virus detection are required to adopt early measures that can prevent virus spread. However, current methods based on the ...
Dynamic signal processing by ribozyme-mediated RNA circuits to control gene expression

Shen, Shensi; Rodrigo Tarrega, Guillermo; Prakash, Satya; Majer, Eszter; Landrain, T.E.; Kirov, Boris; Daros Arnau, Jose Antonio; Jaramillo, Alfonso (Oxford University Press (OUP), 2015-05-26)

[EN] Organisms have different circuitries that allow converting signal molecule levels to changes in gene expression. An important challenge in synthetic biology involves the de novo design of RNA modules enabling dynamic ...
Engineering of CRISPR-Cas9-Based Systems for Diagnostics and Biocomputing

Márquez Costa, Rosa (Universitat Politècnica de València, 2024-10-19)

[ES] Los sistemas CRISPR-Cas se basan en un mecanismo del sistema inmune adaptativo que se encuentra en bacterias y arqueas. Funcionan utilizando endonucleasas guiadas por ARN (proteínas Cas) para localizar y reconocer ...
Engineering post-transcriptional regulation of gene expression with RNA-binding proteins

Dolcemascolo, Roswitha (Universitat Politècnica de València, 2024-01-23)

[ES] La biología sintética tiene como objetivo diseñar y construir nuevos sistemas biológicos con funciones deseadas. Los circuitos basados en el control transcripcional han tenido preponderancia en este campo tras el ...
Estudio del uso del sistema CRISPR-Cas13 para la regulación de la expresión génica in vivo y para aplicaciones de diagnóstico in vitro

Soria Gonzalvo, Ángela (Universitat Politècnica de València, 2022-09-06)

[ES] Los organismos procariotas presentan sistemas inmunológicos que, guiados por RNA, escinden elementos genéticos desconocidos mediante un sistema basado en repeticiones palindrómicas cortas interespaciadas agrupadas ...
Exploring the Dynamics and Mutational Landscape of Riboregulation with a Minimal Synthetic Circuit in Living Cells

Rodrigo Tarrega, Guillermo; Majer, Eszter; Prakash, Satya; Daros Arnau, Jose Antonio; Jaramillo, Alfonso; Poyatos, Juan F. (Biophysical Society, 2015-09-01)

[EN] The regulation of gene expression, triggered by conformational changes in RNA molecules, is widely observed in cellular systems. Here, we examine this mode of control by means of a model-based design and construction ...
Full design automation of multi-state RNA devices to program gene expression using energy-based optimization

Rodrigo Tarrega, Guillermo; Landrain, Thomas E.; Majer, Eszter; Daros Arnau, Jose Antonio; Jaramillo, Alfonso (Public Library of Science, 2013-08)

[EN] Small RNAs (sRNAs) can operate as regulatory agents to control protein expression by interaction with the 59 untranslated region of the mRNA. We have developed a physicochemical framework, relying on base pair ...
Functionalization of an Antisense Small RNA

Rodrigo Tarrega, Guillermo; Prakash, Satya; Cordero-Cucart, María Teresa; Kushwaha, Manish; Jaramillo, Alfonso (Elsevier, 2016-02-27)

[EN] In order to explore the possibility of adding new functions to preexisting genes, we considered a framework of riboregulation. We created a new riboregulator consisting of the reverse complement of a known riboregulator. ...
Gene regulation by a protein translation factor at the single-cell level

Dolcemascolo, Roswitha; Goiriz, Lucas; Montagud-Martínez, Roser; Rodrigo Tarrega, Guillermo (Public Library of Science, 2022-05-06)

[EN] Gene expression is inherently stochastic and pervasively regulated. While substantial work combining theory and experiments has been carried out to study how noise propagates through transcriptional regulations, the ...
Genetic redundancies enhance information transfer in noisy regulatory circuits

Rodrigo Tarrega, Guillermo; Poyatos, Juan F. (Public Library of Science, 2016-10)

[EN] Cellular decision making is based on regulatory circuits that associate signal thresholds to specific physiological actions. This transmission of information is subjected to molecular noise what can decrease its ...