Vila, Carlos; Rostoll-Berenguer, Jaume; Sánchez-García, Rubén; Blay, Gonzalo; Fernandez, Isabel; Muñoz Roca, María Del Carmen; Pedro, Jose R.(American Chemical Society, 2018-06-15)
[EN] An asymmetric catalytic reaction of hydroxyindoles with nitroalkenes leading to the Friedel-Crafts alkylation in the carbocyclic ring of indole is presented. The method is based on the activating/directing effects of ...
Blay, Gonzalo; Fernandez, Isabel; Monje, Belen; Muñoz Roca, María Del Carmen; Pedro, Jose R.; Vila, Carlos(Elsevier, 2006-09-22)
[EN] An approach for the synthesis of chiral non-racemic 2-substituted-1,4-diketones from (S)-mandelic acid and ¿,ß-enones has been developed. The reaction of lithium enolate of the 1,3-dioxolan-4-one derived from optically ...