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Listar por autor "Gago Zachert, Selma Persida"

Mostrando ítems 1-14 de 14

Different rates of spontaneous mutation of chloroplastic and nuclear viroids as determined by high-fidelity ultra-deep sequencing

López-Carrasco, María Amparo; Ballesteros Martínez, Cristina; Sentandreu, V.; Delgado Villar, Sonia Guadalupe; Gago Zachert, Selma Persida; FLORES PEDAUYE, RICARDO; Sanjuan Verdeguer, Rafael (Public Library of Science, 2017-09-14)

[EN] Mutation rates vary by orders of magnitude across biological systems, being higher for simpler genomes. The simplest known genomes correspond to viroids, subviral plant replicons constituted by circular non-coding ...
Double-stranded RNA interferes in a sequence-specific manner with the infection of representative members of the two viroid families

CARBONELL, ALBERTO; Martínez de Alba, Ángel-Emilio; FLORES PEDAUYE, RICARDO; Gago, Selma (Elsevier, 2008-02-05)

[EN] Infection by viroids, non-protein-coding circular RNAs, occurs with the accumulation of 21¿24 nt viroid-derived small RNAs (vd-sRNAs) with characteristic properties of small interfering RNAs (siRNAs) associated to RNA ...
Effects of the trinucleotide preceding the self-cleavage site on eggplant latent viroid hammerheads: differences in co- and post-transcriptional self-cleavage may explain the lack of trinucleotide AUC in most natural hammerheads

CARBONELL, ALBERTO; La Peña Del Rivero, Marcos De; FLORES PEDAUYE, RICARDO; Gago, Selma (Oxford University Press, 2006-11)

[EN] Eggplant latent viroid (ELVd) can form stable hammerhead structures in its (+) and (¿) strands. These ribozymes have the longest helices I reported in natural hammerheads, with that of the ELVd (+) hammerhead being ...
ICTV Virus Taxonomy Profile: Ophioviridae

Garcia, M.L; Dal Bo, Elena; da Graca, John V.; Gago Zachert, Selma Persida; Hammond, J; Moreno, Pedro; Natsuaki, T; Pallás Benet, Vicente; Navarro Bohigues, José Antonio; Reyes, Carina; Luna, Gabriel Robles; Sasaya, Takahide; Tzanetakis, Loannis E.; Vaira, Anna Maria; Verbeek, Martin (Microbiology Society, 2017)

[EN] The Ophioviridae is a family of filamentous plant viruses, with single-stranded negative, and possibly ambisense, RNA genomes of 11.3-12.5 kb divided into 3-4 segments, each encapsidated separately. Virions are naked ...
In memoriam of Ricardo Flores: The career, achievements, and legacy of an inspirational plant virologist

Pallás Benet, Vicente; HERNANDEZ FORT, CARMEN; Marcos, Jose F.; Daròs, José-Antonio; Ambrós, Silvia; Navarro, Beatriz; NAVARRO BOHIGUES, JOSE ANTONIO; La Peña Del Rivero, Marcos De; Gago-Zachert, Selma; Gas, Maria E.; CARBONELL, ALBERTO; López Del Rincón, Carmelo; Martínez-De Alba, Angel E.; Di Serio, Francesco; Moreno, Pedro (Elsevier, 2022-04-15)

[EN] Ricardo Flores (1947-2020) focused his research on the identification, replication, pathogenesis, and evolution of viroids, the minimal non-protein-coding circular RNAs (250-400 nt) able to replicate and incite diseases ...
Resistencia a viroides inducida por ribozimas de cabeza de martillo y RNAs interferentes

Carbonell Olivares, Alberto (Universitat Politècnica de València, 2008-05-07)

Los viroides, los agentes infecciosos conocidos más simples, están constituidos por una molécula circular de RNA monocatenario. A pesar de su pequeño tamaño (246-401 nt) y de no codificar proteínas, son capaces de replicarse ...
Role of RNA silencing in plant-viroid interactions and in viroid pathogenesis

Di Serio, Francesco; Owens, Robert A.; Navarro, Beatriz; Serra, Pedro; Martínez De Alba, Angel Emilio; Delgado Villar, Sonia Guadalupe; CARBONELL, ALBERTO; Gago-Zachert, Selma (Elsevier, 2023-01-02)

[EN] Viroids are small, single-stranded, non-protein coding and circular RNAs able to infect host plants in the absence of any helper virus. They may elicit symptoms in their hosts, but the underlying molecular pathways ...
Rolling-circle replication of viroids, viroid-like satellite RNAs and hepatitis delta virus: variations on a theme

Flores Pedauye, Ricardo; Grubb, Clayton Douglas; Elleuch, Amine; Nohales Zafra, Maria Angeles; Delgado, Sonia; Gago Zachert, Selma Persida (Taylor & Francis, 2011-04)

[EN] Viroids and viroid-like satellite RNAs from plants, and the human hepatitis delta virus (HDV) RNA share some properties that include small size, circularity and replication through a rolling-circle mechanism. Replication ...
Symptomatic plant viroid infections in phytopathogenic fungi: a request for a critical reassessment

Serra, Pedro; CARBONELL, ALBERTO; Navarro, Beatriz; Gago Zachert, Selma; Li, Shigang; Di Serio, Francesco; FLORES PEDAUYE, RICARDO (Proceedings of the National Academy of Sciences, 2020-05-12)
The transcription initiation sites of eggplant latent viroid strands map within distinct motifs in their in vivo RNA conformations

López-Carrasco, María Amparo; Gago Zachert, Selma Persida; Mileti, Giuseppe; Minoia, Sofia; Flores Pedauye, Ricardo; Delgado Villar, Sonia Guadalupe (Taylor & Francis, 2016-01-02)

[EN] Eggplant latent viroid (ELVd), like other members of family Avsunviroidae, replicates in plastids through a symmetric rolling-circle mechanism in which elongation of RNA strands is most likely catalyzed by a nuclear-encoded ...
Trans-cleaving hammerhead ribozymes with tertiary stabilizing motifs: in vitro and in vivo activity against a structured viroid RNA

Carbonell, Alberto; Flores Pedauye, Ricardo; Gago Zachert, Selma Persida (Oxford University Press (OUP): Policy C - Option B, 2011)

[EN] Trans-cleaving hammerheads with discontinuous or extended stem I and with tertiary stabilizing motifs (TSMs) have been tested previously against short RNA substrates in vitro at low Mg2+ concentration. However, the ...
Viroid replication: Rolling-circles, enzymes and ribozymes

FLORES PEDAUYE, RICARDO; Gas, María-Eugenia; Molina-Serrano, Diego; Nohales, María-Ángeles; CARBONELL, ALBERTO; Gago, Selma; La Peña Del Rivero, Marcos De; Daròs, José-Antonio (MDPI AG, 2009-09)

[EN] Viroids, due to their small size and lack of protein-coding capacity, must rely essentially on their hosts for replication. Intriguingly, viroids have evolved the ability to replicate in two cellular organella, the ...
Viroids: survivors from the RNA world?

FLORES PEDAUYE, RICARDO; Gago Zachert, Selma Persida; SERRA ALFONSO, PEDRO; Sanjuan Verdeguer, Rafael; ELENA FITO, SANTIAGO FCO (Annual Reviews, 2014)

[EN] Because RNA can be a carrier of genetic information and a biocatalyst, there is a consensus that it emerged before DNA and proteins, which eventually assumed these roles and relegated RNA to intermediate functions. ...
Viroids: the minimal non-coding RNAs with autonomous replication

FLORES PEDAUYE, RICARDO; Delgado Villar, Sonia Guadalupe; Gas, María-Eugenia; CARBONELL, ALBERTO; Molina, Diego; Gago, Selma; La Peña Del Rivero, Marcos De (John Wiley & Sons, 2004-06-01)

[EN] Viroids are small (246¿401 nucleotides), non-coding, circular RNAs able to replicate autonomously in certain plants. Viroids are classified into the families Pospiviroidae and Avsunviroidae, whose members replicate ...