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Listar por autor "Abasolo, Ibane"

Mostrando ítems 1-4 de 4

Alteration of the Mitochondrial Effects of Ceria Nanoparticles by Gold: An Approach for the Mitochondrial Modulation of Cells Based on Nanomedicine

Gutiérrez-Carcedo, Patricia; Navalón Oltra, Sergio; Simó, Rafael; Setoain, Xavier; Aparicio-Gómez, Carolina; Abasolo, Ibane; Victor, Victor Manuel; García Gómez, Hermenegildo; Herance, José Raúl (MDPI AG, 2020-04)

[EN] Ceria nanoparticles are cell compatible antioxidants whose activity can be enhanced by gold deposition and by surface functionalization with positive triphenylphosphonium units to selectively target the mitochondria. ...
Glutathione-sensitive nanoplatform for monitored intracellular delivery and controlled release of Camptothecin

Muniesa Lajara, Carlos; Vicente Vilas, Victor; Quesada Vilar, Manuel; SAEZ-ATIENZAR, SARA; BLESA-BLESA, JOSE RAFAEL; Abasolo, Ibane; Fernández, Yolanda; Botella Asuncion, Pablo (Royal Society of Chemistry, 2013)

[EN] We report the design, synthesis, characterization and in vitro testing of a novel nanodrug based on a covalent linking model that allows intracellular controlled release of the pharmaceutical payload. A new synthetic ...
Semisynthesis, Cytotoxic Activity, and Oral Availability of New Lipophilic 9-Substituted Camptothecim Derivatives

Rodríguez Berna, Guillermo; Díaz Cabañas, Mª José; Mangas Sanjuan, Víctor; Gonzalez Alvarez, Marta; Gonzalez Álvarez, Isabel; Abasolo, Ibane; Simo Schwartz, Jr.; Bermejo, Marival; Corma Canós, Avelino (American Chemical Society, 2013-05-28)

Despite that 9-substituted camptothecins are promising candidates in cancer therapy, the limited accessibility to this position has reduced the studies of these derivatives to a few standard modifications. We report herein ...
Surface-modified silica nanoparticles for tumor-targeted delivery of camptothecin and its biological evaluation

Botella Asuncion, Pablo; Abasolo, Ibane; Fernández, Yolanda; Muniesa Lajara, Carlos; Miranda, Sonia; Quesada Vilar, Manuel; Ruiz Carrascal, Jorge; Schwart, Simó; Corma Canós, Avelino (Elsevier, 2011)

[EN] Here we report the design, synthesis and biological evaluation of surface-modified silica nanoparticles (SNP) for the delivery of camptothecin (CPT). Drug has been covalently linked to the nanoparticle through an ester ...

Mostrando ítems 1-4 de 4

Listar por autor "Abasolo, Ibane"

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Listar por autor "Abasolo, Ibane"