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Listar por autor "Bañuls Polo, María José"

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Análisis digital preliminar de adenocarcinoma pancreático

Rubio Soria, Raquel (Universitat Politècnica de València, 2023-07-21)

[ES] En los últimos años, se ha podido observar un análisis digital microscópico más evidente de la oncología a través de la patología digital, la cual cada vez desempeña un papel más importante en la práctica clínica. De ...
Anclaje de balizas moleculares a soportes sólidos mediante química click. Aplicación a la detección de microRNAs asociados a cáncer y estudio de prestaciones

Peña Gil, Nazaret (Universitat Politècnica de València, 2018-09-19)

[EN] This work has been carried out within the framework of the European project SAPHELY (H2020-ICT-644242) which aims to develop a point of care device (POC) that allows early diagnosis of different diseases through ...
Bio-Photonic Sensing Cells over transparent substrates for anti-gestrinone antibodies biosensing

Sanza, F.J.; Holgado, M.; Ortega Higueruelo, Francisco José; Casquel Del Campo, Rafael; López-Romero, D.; Bañuls Polo, Mª José; Laguna, Mari Fe; Barrios, C.A.; Puchades Pla, Rosa; Maquieira Catala, Ángel (Elsevier, 2011)

[EN] In a previous work we introduced the term Bio-Photonic Sensing Cells (BICELLs), referred to periodic networks of nano-pillar suitable for biosensing when are vertically interrogated. In this article, we demonstrate ...
Biomolecular Interaction Analysis of Gestrinone-anti-Gestrinone Using Arrays of High Aspect Ratio SU-8 Nanopillars

Ortega Higueruelo, Francisco José; Bañuls Polo, Mª José; Sanza, Francisco J.; Casquel, Rafael; Laguna, Mari Fe; Holgado, Miguel; López-Romero, David; Barrios, Carlos A.; Maquieira Catala, Ángel; Puchades Pla, Rosa (MDPI, 2012)

In this paper, label-free biosensing for antibody screening by periodic lattices of high-aspect ratio SU-8 nano-pillars (BICELLs) is presented. As a demonstration, the determination of anti-gestrinone antibodies from whole ...
Caracterización del perfil metabolómico asociado a la metástasis ganglionar en pacientes con melanoma mediante 1H-RMN

Martínez Fernández de Córdova, Paula (Universitat Politècnica de València, 2018-09-18)

[ES] Entre las enfermedades oncológicas, que actualmente constituyen la principal causa de muerte en el mundo, el cáncer de piel conforma el grupo más frecuente. En particular el melanoma destaca por su potencial ...
Chemical silicon surface modification and bioreceptor attachment to develop competitive integrated photonic biosensors

Escorihuela Fuentes, Jorge; Bañuls Polo, Mª José; García Castelló, Javier; Toccafondo, Veronica; García-Rupérez, Jaime; Puchades Pla, Rosa; Maquieira Catala, Ángel (Springer Verlag, 2012)

[EN] Methodology for the functionalization of siliconbased materials employed for the development of photonic label-free nanobiosensors is reported. The studied functionalization based on organosilane chemistry allowed ...
Chemical Surface Modifications development of Silicon Based Label Free Integrated Optical (IO) Biosensors: A Review

Bañuls Polo, Mª José; Puchades Pla, Rosa; Maquieira Catala, Ángel (Elsevier Masson, 2013-01-23)

[EN] Increasing interest has been paid to label-free biosensors in recent years. 11 Among them, refractive index (RI) optical biosensors enable high density and the chip-12 scale integration of optical components. This ...
Combination of nanophotonic biosensors and light-assisted immobilization procedures for the detection of cardiac biomarkers

Sabek, Jad (Universitat Politècnica de València, 2019-09-02)

[ES] El cuidado de la salud es un campo en el que la detección precoz de enfermedades está cobrando cada vez más importancia. Hoy en día, profesionales y ciudadanos demandan que las técnicas de diagnóstico sean de alta ...
Cost-effective SU-8 micro-structures by DUV excimer laser lithography for label-free biosensing

Sanza, F. J.; Laguna, Mari Fé; Casquel Del Campo, Rafael; Holgado, M.; Angulo Barrios, Carlos; Ortega Higueruelo, Francisco José; López-Romero, D.; García-Ballesteros, J.J.; Bañuls Polo, Mª José; Maquieira Catala, Ángel; Puchades Pla, Rosa (Elsevier, 2011-04-01)

Cost-effective SU-8 micro-structures on a silicon substrate were developed using 248 nm excimer laser KrF projection, studying the influence of the different variables on the final pattern geometry, finding out that the ...
Covalent attachment of biotinylated molecular beacons via thiol-ene coupling. A study on conformational changes upon hybridization and streptavidin binding

Gonzalez-Lucas, Daniel; Bañuls Polo, María-José; García-Rupérez, Jaime; Maquieira Catala, Ángel (Springer-Verlag, 2017)

[EN] The authors describe a method for the detection of DNA by using immobilized molecular beacons (MBs) on the surface of silicon, with a view on possible application in biosensing. MB hybridization and protein recognition ...
Desarrollo de metodologías de anclaje de anticuerpos basadas en reacciones de click-chemistry. Aplicación a la detección de marcadores cardíacos

Poveda Úbeda, Adrián (Universitat Politècnica de València, 2016-09-02)

[ES] La detección temprana de enfermedades muchas veces se basa en la medición de una o varias proteínas y/o en el análisis genético. El formato microarray es un buen candidato para aplicarlo a los dispositivos de detección ...
Desarrollo de microarrays de altas prestaciones basados en atrapamiento con un hidrogel. Aplicación a inmunoensayo y ensayos genéticos

Guerrero Picó, Ismael (Universitat Politècnica de València, 2015-09-04)

[ES] La detección temprana de enfermedades muchas veces se basa en la medición de una o varias proteínas y/o en el análisis genético. El formato microarray es un buen candidato para aplicarlo a los dispositivos de detección ...
Design and Characterization of ITO-Covered Resonant Nanopillars for Dual Optical and Electrochemical Sensing

Tramarin, Luca; Casquel, Rafael; Gil-Rostra, Jorge; González Martínez, Miguel Ángel; Herrero-Labrador, Raquel; Murillo, Ana María M.; Laguna, María Fé; Bañuls Polo, María-José; González-Elipe, Agustín R.; Holgado, Miguel (MDPI AG, 2022-10)

[EN] In this work we present a dual optical and electrochemical sensor based on SiO2/Si3N4 resonant nanopillars covered with an indium tin oxide (ITO) thin film. A 25-30 nm thick ITO layer deposited by magnetron sputtering ...
Designing stable lead halide perovskite nanocrystals: From a single particle to nanocomposites

Collantes-Pablo, Cynthia; Teixeira, William; González-Pedro, Victoria; Bañuls Polo, María-José; Maquieira, Angel (Elsevier BV, 2023-04)

[EN] Metal halide perovskite nanocrystals have attracted substantial interest given their easy manufacturing, superior Photoluminiscence Quantum Yield and striking optical properties. Despite the huge potential of such ...
Development of a versatile biotinylated material based on SU-8

Ortega Higueruelo, Francisco José; Bañuls Polo, María-José; Sanza, Francisco J.; Laguna, Mari Fe; Holgado Bolaños, Miguel; Casquel Del Campo, Rafael; Angulo Barrios, Carlos; López Romero, David; Maquieira Catala, Ángel; Puchades, Rosa (Royal Society of Chemistry, 2013)

[EN] The negative epoxy-based SU-8 photoresist has a wide variety of applications within the semiconductor industry, photonics and lab-on-a-chip devices, and it is emerging as an alternative to silicon-based devices for ...
Development of oligonucleotide microarrays onto si-based surfaces via thioether linkage mediated by UV irradiation

Escorihuela Fuentes, Jorge; Bañuls Polo, Mª José; Puchades Pla, Rosa; Maquieira Catala, Ángel (American Chemical Society, 2012)

Selective covalent immobilization of thiolated oligonucleotides onto an epoxy-functionalized silicon-substrate can be achieved via light radiation (365 nm). Following this approach, thiol-modified oligonucleotide probes ...
Direct and label-free monitoring oligonucleotide immobilization, non-specific binding and DNA biorecognition

López Paz, José Luis; González Martínez, Miguel Ángel; Escorihuela Fuentes, Jorge; Bañuls Polo, Mª José; Puchades Pla, Rosa; Maquieira Catala, Ángel (Elsevier, 2014-03-01)

DNA binding chemistry on silicon surface has been investigated. Aminated oligonucleotide probes were immobilized on the chip surface by chemical silanization and further covalent attachment. The chemistries employed were ...
Direct covalent attachment of DNA microarrays by rapid thiol-ene "click" chemistry

Escorihuela Fuentes, Jorge; Bañuls Polo, María-José; Grijalvo-Torrijo, Santiago; Eritja, Ramón; Puchades, Rosa; Maquieira Catala, Ángel (American Chemical Society, 2014-03)

[EN] A rapid strategy for the covalent immobilization of DNA onto silicon-based materials using the UV-initiated radical thiol-ene reaction is presented in this study. Following this approach, thiol- and alkene-modified ...
DNA -based hydrogels for high-performance optical biosensing application

Zezza, Paola; Lucío, María Isabel; Maquieira Catala, Angel; Bañuls Polo, María-José (Elsevier, 2022-07-01)

[EN] Analyte-sensitive DNA-based hydrogels find multiple applications in the field of biosensors due to their adaptable nature. Here, the design of DNA-based hydrogel and its application as sensing platform for the detection ...
DNA microarrays on silicon surfaces through thiol-ene chemistry

Escorihuela Fuentes, Jorge; Bañuls Polo, Mª José; Puchades Pla, Rosa; Maquieira Catala, Ángel (Royal Society of Chemistry, 2012)

The potential of thiol-ene chemistry as a selective strategy to functionalize silicon materials for DNA microarraying is demonstrated and applied to discriminate genetic variations. © 2012 The Royal Society of Chemistry.