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Listar por autor "Rodríguez Hernández, Carlos Javier"

Mostrando ítems 1-4 de 4

Anti-diabetic and anti-obesity agent sodium tungstate enhances GCN pathway activation through Glc7p inhibition

Rodríguez Hernández, Carlos Javier; Guinovart, J.J.; Murguía, Jose R. (ElsevierWiley, 2012-02-03)

[EN] Tungstate counteracts diabetes and obesity in animal models, but its molecular mechanisms remain elusive. Our Saccharomyces cerevisiae-based approach has found that tungstate alleviated the growth defect induced by ...
eIF2 kinases mediate beta-lapachone toxicity in yeast and human cancer cells

MENACHO MARQUEZ, Mauricio Ariel; Rodríguez Hernández, Carlos Javier; Villaronga, Ángeles; Pérez Valle, Jorge; Gadea Vacas, José; Belandia, Borja; Murguía Ibáñez, José Ramón (Taylor & Francis, 2015-03)

[EN] In this work we focus on the problem of approximating multiple roots of nonlinear equations. Multiple roots appear in some applications such as the compression of band-limited signals and the multipactor effect in ...
Identificación de nuevos mecanismos moleculares del inmunosupresor FK506 en Saccharomyces cervisiae

Rodríguez Hernández, Carlos Javier (Universitat Politècnica de València, 2008-05-06)

El inmunosupresor FK506 (Tacrolimus, Prograf) ha incrementado la tasa de supervivencia del trasplante de órganos. FK506 ejerce su acción inmunosupresora mediante la inhibición de la fosfatasa calcineurina en células T ...
Sodium tungstate modulates ATM function upon DNA damage

Rodríguez Hernández, Carlos Javier; Llorens Agost, M.; Calbó, J.; Murguía, Jose R.; Guinovart, J.J. (Wiley, 2013-05-21)

[EN] Both radiotherapy and most effective chemotherapeutic agents induce different types of DNA damage. Here we show that tungstate modulates cell response to DNA damaging agents. Cells treated with tungstate were more ...

Mostrando ítems 1-4 de 4

Listar por autor "Rodríguez Hernández, Carlos Javier"

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Listar por autor "Rodríguez Hernández, Carlos Javier"