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Listar por autor "García Lainez, Guillermo"

RiuNet: Repositorio Institucional de la Universidad Politécnica de Valencia

Listar por autor "García Lainez, Guillermo"

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    Chemical tuning for potential antitumor fluoroquinolones 
    Anaya-González, Cristina; Soldevila Serrano, Sonia; García-Laínez, Guillermo; Bosca Mayans, Francisco; Andreu Ros, María Inmaculada (Elsevier, 2019-09)
    [EN] Phototoxic effects of 6,8 dihalogenated quinolones confers to this type of molecules a potential property as photochemotherapeutic agents. Two photodehalogenation processes seem to be involved in the remarkable ...
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    Cytotoxic sub-nanometer aqueous platinum clusters as potential antitumoral agents 
    Greco, Rossella; García-Laínez, Guillermo; Oliver-Meseguer, Judit; Marini, Carlo; Domínguez, Irene; Lopez-Haro, Miguel; Hernandez-Garrido, Juan Carlos; Cerón-Carrasco, José Pedro; Andreu, Inmaculada; Leyva Perez, Antonio (Royal Society of Chemistry, 2022-12-06)
    [EN] Ligand-free sub-nanometer metal clusters (MCs) of Pt, Ir, Rh, Au and Cu, are prepared here in neat water and used as extremely active (nM) antitumoral agents for HeLa and A2870 cells. The preparation just consists of ...
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    Enhanced photo(geno)toxicity of demethylated chlorpromazine metabolites 
    Palumbo, Fabrizio; García Lainez, Guillermo; Limones Herrero, Daniel; Coloma, María Dolores; Escobar, Javier; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel; Andreu Ros, María Inmaculada (Elsevier, 2016)
    Chlorpromazine (CPZ) is an anti-psychotic drug widely used to treat disorders such as schizophrenia or manic-depression. Unfortunately, CPZ exhibits undesirable side effects such as phototoxic and photoallergic reactions ...
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    Polipéptidos moduladores de interacciones proteína-proteína mediadas por dominios CARD 
    García Lainez, Guillermo (Universitat Politècnica de València, 2012-05-18)
    El dominio CARD (Caspase recruitment domain) se encuentra presente en un gran número de proteínas. Inicialmente fue identificado como parte de la maquinaria de activación de las proteasas denominadas caspasas. De hecho, ...