[EN] Senescent cells accumulate in multiple aging-associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal beta-galactosidase ...
Cerezo-Navarrete, Christian; Mathieu, Yannick; Puche Panadero, Marta; Morales, Cristina; Concepción Heydorn, Patricia; Martínez-Prieto, Luis Miguel; Corma Canós, Avelino(The Royal Society of Chemistry, 2021-01-21)
[EN] Mono and bimetallic platinum-ruthenium nanoparticles have been generated on N-doped graphene (NH2-rGO) following an organometallic approach. Surface and structural studies confirmed the formation of bimetallic MNPs ...
Giménez Morales, Cristina(Universitat Politècnica de València, 2016-04-22)
[EN] The present PhD thesis, which is entitled "Design of new bio-gated nanodevices for advanced communication processes and targeted controlled release of therapeutic agents" is focused on the development of new functional ...
[EN] Colon targeted drug delivery is highly relevant not only to treat colonic local diseases but also for systemic therapies. Mesoporous silica nanoparticles (MSNs) have been demonstrated as useful systems for controlled ...
Giménez Morales, Cristina; de la Torre, Cristina; Gorbe, Mónica; Aznar, Elena; Sancenón Galarza, Félix; Murguía, Jose R.; Martínez-Máñez, Ramón; Marcos Martínez, María Dolores; Amoros del Toro, Pedro Jose(American Chemical Society, 2015-03-31)
In recent years, mesoporous silica nanoparticles (MSNs) have been used as effective supports for the development of controlled-release nanodevices that are able to act as multifunctional delivery platforms for the encapsulation ...
Aznar Gimeno, Elena; Villalonga, Reynaldo; Giménez Morales, Cristina; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Martínez Mañez, Ramón; Díez, Paula; Pingarrón, José M.; Amoros del Toro, Pedro(Royal Society of Chemistry, 2013-05-15)
[EN] A new gated nanodevice design able to control cargo delivery using glucose as a trigger and cyclodextrin-modified glucose oxidase as a capping agent is reported.
El Sayed Shehata Nasr, Sameh; Giménez Morales, Cristina; Aznar Gimeno, Elena; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Licchelli, Maurizio(Royal Society of Chemistry, 2015)
[EN] Mesoporous silica nanoparticles loaded with safranin O and capped with disulfide-containing oligo(ethylene glycol) chains were used for the selective and sensitive fluorimetric detection of glutathione.
Ultimo, Amelia; De La Torre-Paredes, Cristina; Giménez, Cristina; Aznar, Elena; Coll, Carmen; Marcos Martínez, María Dolores; Murguía, Jose R.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix(The Royal Society of Chemistry, 2020-07-07)
[EN] Nanoparticle-cell-nanoparticle communication by stigmergy was demonstrated using two capped nanodevices. The first community of nanoparticles (i.e.S(RA)(IFN)) is loaded with 9-cis-retinoic acid and capped with ...
Santos Figueroa, Luis Enrique; Giménez Morales, Cristina; Agostini, Alessandro; Aznar Gimeno, Elena; Marcos Martínez, María Dolores; Sancenón Galarza, Félix; Martínez Mañez, Ramón; Amoros del Toro, Pedro Jose(Wiley-VCH Verlag, 2013-12-16)
[EN] In water and wine: Chromofluorogenic detection of the sulfite anion in pure water was accomplished by using a new hybrid organic-inorganic material that contained a probe entrapped in hydrophobic biomimetic cavities. ...
Santos Figueroa, Luis Enrique; Giménez Morales, Cristina; Agostini, Alessandro; Aznar Gimeno, Elena; Marcos Martínez, María Dolores; Sancenón Galarza, Félix; Martínez Mañez, Ramón; Amoros del Toro, Pedro(Wiley-VCH Verlag, 2013-12-16)
[EN] Chromofluorogenic detection of the sulfite anion in pure water was accomplished by using a new hybrid organic¿inorganic material that contained a probe entrapped in hydrophobic biomimetic cavities. This material was ...
Juarez, L. Alberto; Añón, Elena; Giménez Morales, Cristina; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Costero Nieto, Ana María; Gaviña, Pablo; Parra Álvarez, Margarita; Bernardos Bau, Andrea(Wiley, 2016-09)
A new hybrid material based on sulforhodamine-B dye-loaded silica mesoporous nanoparticles capped with a self-immolative gate has been synthesized and characterized. The gated material's controlled release behavior is ...
Ultimo, Amelia; Giménez Morales, Cristina; BARTOVSKY, PAVEL; Aznar, Elena; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Amoros del Toro, Pedro Jose; Bernardo, Ana R.; Martínez-Máñez, Ramón; Jiménez Lara, Ana M.; Murguía, Jose R.(Wiley, 2016-01-26)
The authors describe herein a Toll-like receptor 3 (TLR3) targeting delivery system based on mesoporous silica nanoparticles capped with the synthetic double stranded RNA polyinosinic-polycytidylic acid (poly(I:C)) for ...
Giménez Morales, Cristina; Climent Terol, Estela; Aznar Gimeno, Elena; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Amoros del Toro, Pedro Jose; Rurack, Knut(Wiley-VCH Verlag, 2014-11-10)
The design of comparatively simple and modularly
configurable artificial systems able to communicate through
the exchange of chemical messengers is, to the best of our
knowledge, an unexplored field. As a proof-of-concept, ...
Giménez Morales, Cristina; Climent Terol, Estela; Aznar Gimeno, Elena; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Amoros del Toro, Pedro Jose; Rurack, Knut(Wiley-VCH Verlag, 2014)
Das Design von vergleichsweise einfachen und
modular konfigurierbaren k nstlichen Systemen, die ber den
Austausch von chemischen Botenstoffen miteinander kommunizieren
kçnnen, ist unseres Wissens ein bislang ...