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Listar por autor "Ródenas Rochina, Joaquín"

Mostrando ítems 1-20 de 20

Antifouling zwitterionic pSBMA-MSN particles for biomedical applications

Beltrán-Osuna, A.A.; Ródenas Rochina, Joaquín; Gómez Ribelles, José Luís; Perilla-Perilla, Jairo Ernesto (John Wiley & Sons, 2019-03)

[EN] Mesoporous silica nanoparticles (MSNs) are one of the most promising nanocarriers in biomedicine. Nonetheless, surface modification has been pointed out as a condition necessary for drug delivery applications, where ...
Assemblable 3D biomimetic microenvironment for hMSC osteogenic differentiation

Martins, Luis A.; García-Parra, Nadia; Ródenas Rochina, Joaquín; Cordón, Lourdes; Sempere, Amparo; Ribeiro, Clarisse; Lanceros-Méndez, Senentxu; Gomez-Ribelles, Jose Luis (IOP Publishing, 2024-11-01)

[EN] Adequate simulation mimicking a tissue's native environment is one of the elemental premises in tissue engineering. Although various attempts have been made to induce human mesenchymal stem cells (hMSC) into an ...
Biomateriales poliméricos flexibles para fusiones vertebrales

Primo Capella, Victor; Lara Sáez, Irene; Avila Carrasco, Carolina; Montaner Murgui, Celia; Lebourg ., Myriam Madeleine; Ródenas Rochina, Joaquín; Garagorri Ganchegui, Nerea; Bresó Peris, Magdalena; Atienza Vicente, Carlos Manuel (Universitat Politècnica de València. Instituto de Biomecánica de Valencia, 2011-06)

[EN] In the framework of the CENIT INTELIMPLANT, the consortium composed by TEQUIR, S.L., the Instituto de Biomecánica (IBV) and other regional and nacional research groups have carried out the development, ...
Biomimetic microgels for articular cartilage regeneration. A minipig knee model

Milián, Lara; Ródenas Rochina, Joaquín; Alcorisa, Ignacio; Plá-Salom, Júlia; Aguilar Hernández, Ángel; Gómez-Tejedor, José-Antonio; Gallego-Ferrer, Gloria; Sancho-Tello, María; Monllau, Juan Carlos; Mata Roig, Manuel; Gómez Ribelles, José Luís (Elsevier, 2024-10-24)

[EN] The aim of this study is to explore, with an in vivo model, the regeneration of articular cartilage that can be obtained with a strategy that combines the stimulation of the subchondral bone with the implantation of ...
Chondrocytes cultured in an adhesive macroporous scaffold subjected to stirred flow bioreactor behave like in static culture

Gamboa Martínez, Tatiana Carolina; Ródenas Rochina, Joaquín; Rico Tortosa, Patricia María; Lebourg, Myriam Madeleine; Gómez Ribelles, José Luís; Salmerón Sánchez, Manuel; Gallego-Ferrer, Gloria (American Scientific Publishers, 2013)

[EN] The aim of this study was to evaluate whether mechanical stimulation helps to modulate the redifferentiation of human chondrocytes on adhesive 3D substrates. In a previous work, it was shown that chondrocytes seeded ...
Comparative study of PCL-HAp and PCL-bioglass composite scaffolds for bone tissue engineering

Ródenas Rochina, Joaquín; Gómez Ribelles, José Luís; Lebourg, Myriam Annette Madeleine (Springer Verlag, 2013-05)

The aim of this work is to compare the effect of hydroxyapatite (HAp) or bioglass (BG) nanoparticles in a polycaprolactone composite scaffold aimed to bone regeneration. To allow a comparison of the influence of both types ...
Compositional changes to synthetic biodegradable scaffolds modulate the influence of hydrostatic pressure on chondrogenesis of mesenchymal stem cells

Ródenas Rochina, Joaquín; Kelly, Daniel John; Gómez Ribelles, José Luís; Lebourg, Myriam Madeleine (IOP Publishing, 2016)

[EN] Mechanical cues such as hydrostatic pressure (HP) are known to regulate mesenchymal stem cell (MSC) differentiation. The fate of such cells is also strongly influenced by their substrate. The objective of this study ...
Desarrollo y caracterización de un scaffold para ingeniería tisular de hueso

Ródenas Rochina, Joaquín (Universitat Politècnica de València, 2011-09-21)

En este trabajo, se desarrollaron series de scaffolds basados en PCL con refuerzo de hidroxiapatita y Bioglass para evaluar cual es mejor para ingenieria tisular osea. Se midieron las propedades fisicas (comportamiento ...
Different hyaluronic acid morphology modulates primary articular chondrocyte behaviour in hyaluronic acid coated polycaprolactone scaffolds

Lebourg, Myriam Madeleine; Ródenas Rochina, Joaquín; Sousa, Tiago; Mano, Joao; Gómez Ribelles, José Luís (Wiley, 2013-02)

Scaffolds for cartilage tissue engineering should promote both adequate biomechanical environment and chondrogenic stimulation. Hyaluronic acid (HA) has been used in cartilage engineering for its chondrogenic and ...
Effect of electrical stimulation on chondrogenic differentiation of mesenchymal stem cells cultured in hyaluronic acid - Gelatin injectable hydrogels

Vaca-González, Juan Jairo; Clara-Trujillo, Sandra; Guillot-Ferriols, María Teresa; Ródenas Rochina, Joaquín; Sanchis Sánchez, María Jesús; Gómez Ribelles, José Luís; Garzón-Alvarado, Diego Alexander; Gallego-Ferrer, Gloria (Elsevier, 2020-08)

[EN] Electrical stimulation (ES) has provided enhanced chondrogenesis of mesenchymal stem cells (MSCs) cultured in micro-mass without the addition of exogenous growth factors. In this study, we demonstrate for the first ...
Effects of hydroxyapatite filler on long-term hydrolytic degradation of PLLA/PCL

Ródenas Rochina, Joaquín; Vidaurre, Ana; Castilla Cortázar, María Isabel Cecilia; Lebourg ., Myriam Madeleine (Elsevier, 2015)

[EN] Poly(L-lactic acid)(PLLA)/poly(epsilon-caprolactone)(PCL)/hydroxyapatite(HAp) composites appear as promising materials for healing large bone defects. Highly porous PLLA/PCL scaffolds, 80/20, 20/80 weight ratios, ...
Fast degrading polymer networks based on carboxymethyl chitosan

Gámiz González, Mª Amparo; Guldrís-Prada, Paula; Antolinos Turpín, Carmen María; Ródenas Rochina, Joaquín; Vidaurre, Ana; Gómez Ribelles, José Luís (Elsevier, 2017)

[EN] In this work macroporous membrane for mesenchymal stem cells, MSCs, transplant has been developed. The membranes support cell seeding and proliferation and completely degrade in less than one week in "in vitro" culture. ...
Influence of oxygen levels on chondrogenesis of porcine mesenchymal stem cells cultured in polycaprolactone scaffolds

Ródenas Rochina, Joaquín; Kelly, Daniel John; Gómez Ribelles, José Luís; Lebourg, Myriam Madeleine (John Wiley & Sons, 2017)

[EN] Chondrogenesis of mesenchymal stem cells (MSCs) is known to be regulated by a number of environmental factors, including local oxygen levels. The hypothesis of this study is that the response of MSCs to hypoxia is ...
Injectable chitosan-hydroxyapatite hydrogels promote the osteogenic differentiation of mesenchymal stem cells

Ressler, Antonia; Ródenas Rochina, Joaquín; Ivankovic, Marica; Ivankovic, Hrvoje; Rogina, Anamarija; Gallego-Ferrer, Gloria (Elsevier, 2018-10-01)

[EN] Injectable hydrogels have emerged as promising biomaterials for tissue engineering applications. The goal of this study was to evaluate the potential of a pH-responsive chitosan-hydroxyapatite hydrogel to be used as ...
Macroporous thin membranes for cell transplant in regenerative medicine

Antolinos Turpín, Carmen María; Morales Román, Rosa María; Ródenas Rochina, Joaquín; Gómez Ribelles, José Luís; Gómez-Tejedor, José Antonio (Elsevier, 2015-10)

The aim of this paper is to present a method to produce macroporous thin membranes made of poly (ethyl acrylate-co-hydroxyethyl acrylate) copolymer network with varying cross-linking density for cell transplantation and ...
Microfluidics processing of piezoelectric and magnetic responsive electroactive microspheres

Ribeiro-Martins, Luis Amaro; Ródenas Rochina, Joaquín; Salazar, Daniel; Cardoso, VF; Gómez Ribelles, José Luís; Lanceros-Méndez, S. (American Chemical Society, 2022-08)

[EN] Poly(vinylidene fluoride) (PVDF) combined with cobalt ferrite (CFO) particles is one of the most common and effective polymeric magnetoelectric composites. Processing PVDF into its electroactive phase is a mandatory ...
Porous Polylactic Acid-Silica Hybrids: Preparation, Characterization, and Study of Mesenchymal Stem Cell Osteogenic Differentiation

Pandis, Christos; Trujillo Muñoz, Sara; Matos, Joana; Madeira, Sara; Ródenas Rochina, Joaquín; Kripotou, Sotiria; Kyritsis, Apostolos; Mano, Joao F.; Gómez Ribelles, José Luís (Wiley, 2015-02)

A novel approach to reinforce polymer porous membranes is presented. In the prepared hybrid materials, the inorganic phase of silica is synthesized in-situ and inside the pores of aminolyzed polylactic acid (PLA) membranes ...
Scaffold surface modifications and culture conditions as key parameters to develop cartilage and bone tissue engineering implants

Ródenas Rochina, Joaquín (Universitat Politècnica de València, 2015-03-31)

This thesis is focused on the development and evaluation of different hybrid scaffolds for the treatment of injuries in cartilage or bone. These hybrid materials were three-dimensional polycaprolactone macroporous ...
Stability of Biomimetically Functionalised Alginate Microspheres as 3D Support in Cell Cultures

García Briega, María Inmaculada; Ródenas Rochina, Joaquín; Ribeiro Martins, Luis Amaro; Gallego Ferrer, Gloria; Lanceros-Mendez, Senentxu; Sempere Talens, Amparo; Gómez Ribelles, José Luís (MDPIUniversitat Politècnica de València, 2022-10-11)

Alginate hydrogels can be used to develop a three-dimensional environment in which various cell types can be grown. Cross-linking the alginate chains using reversible ionic bonds opens up great possibilities for the ...
Stability of Biomimetically Functionalised Alginate Microspheres as 3D Support in Cell Cultures

García-Briega, María Inmaculada; Ródenas Rochina, Joaquín; Ribeiro-Martins, Luis Amaro; Lanceros-Méndez, Senentxu; Gallego-Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís (MDPI AG, 2022-10)

[EN] Alginate hydrogels can be used to develop a three-dimensional environment in which various cell types can be grown. Cross-linking the alginate chains using reversible ionic bonds opens up great possibilities for the ...