de Luis-Fernández, Beatriz; Morella-Aucejo, Ángela; Llopis-Lorente, Antoni; Godoy-Reyes, Tania Mariel; Villalonga, Reynaldo; Aznar, Elena; Sancenón Galarza, Félix; Martínez-Máñez, Ramón(The Royal Society of Chemistry, 2021-01-28)
[EN] In nature, coordinated communication between different entities enables a group to accomplish sophisticated functionalities that go beyond those carried out by individual agents. The possibility of programming and ...
[EN] Celiac disease is a complex and autoimmune disorder caused by the ingestion of gluten affecting almost 1% of global population. Nowadays an effective treatment does not exist, and the only way to manage the disease ...
[EN] A nanodevice consisted on nanoporous anodic alumina (NAA) supports functionalized with specific and selective antibody-based gatekeepers for the detection of IDH1-R132H mutant enzyme is here reported. Molecular profile ...
[EN] A nanoporous anodic alumina (NAA)-based sensor system for the detection of Mycoplasma was developed through the implementation of "molecular gates" selective to the presence of this bacterium. The capped support showed ...
Pla, Luis; Sancenón Galarza, Félix; Martínez-Bisbal, M.Carmen; Bañuls, Celia; Estañ, Nuria; Botello-Marabotto, Marina Dolores; Aznar, Elena; Sáez, Guillermo; Santiago-Felipe, Sara; Martínez-Máñez, Ramón(The Royal Society of Chemistry, 2021-05-14)
[EN] Many important human diseases, and especially cancer, have been related to the overproduction of 8-oxo-7,8-dihydro-2 '-deoxyguanosine (8-oxo-dG). This molecule is a product of oxidative stress processes over nucleophilic ...
Candel Busquets, Inmaculada; Aznar Gimeno, Elena; Mondragón Martínez, Laura; De la Torre Paredes, Cristina; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Amoros del Toro, Pedro Jose; Guillem, Carmen; Pérez Payá, Enrique; Costero Nieto, Ana María; Gil Grau, Salvador; Parra Álvarez, Margarita(Royal Society of Chemistry, 2012-10-02)
MCM-41 silica nanoparticles were used as inorganic scaffolding to prepare a nanoscopic-capped hybrid material S1, which was able to release an entrapped cargo in the presence of certain enzymes, whereas in the absence of ...
[EN] The construction of communication models at the micro¿/nanoscale involving abiotic nanodevices and living organisms has the potential to open a wide range of applications in biomedical and communication technologies. ...
Melitón Barbancho, Sandra(Universitat Politècnica de València, 2020-07-02)
[ES] El creciente número de prótesis utilizadas en la medicina moderna ha mejorado la calidad de vida de muchos pacientes, sin embargo, han surgido nuevos problemas como consecuencia de su uso. Las tasas de infecciones ...
[EN] In recent times, many approaches have been developed against drug resistant Gram-negative bacteria. However, low-cost high effective materials which could broaden the spectrum of antibiotics are still needed. In this ...
Polo, Lorena; Díaz de Greñu-Puertas, Borja; Della Bella, Elena; Pagani, Stefania; Torricelli, Paola; Vivancos, José-Luis; Ruiz Rico, María; Barat Baviera, José Manuel; Aznar, Elena; Martínez-Máñez, Ramón; Fini, Milena; Sancenón Galarza, Félix(Elsevier, 2018-11)
[EN] Infections represent one of the most frequent causes of arthroplasty revision. Thus, design of new antimi-crobial scaffolds to reduce implant rejections, bone infections and associated medical costs is highlydesired. ...
Caballos-Gómez, María Isabel; Aranda, María Nieves; López-Palacios, Alba; Pla, Luis; Santiago Felipe, Sara; Hernández-Montoto, Andy; Tormo-Mas, María Ángeles; Pemán, Javier; Gómez-Ruiz, María Dolores; Calbuig, Eva; Sánchez-Sendra, Beatriz; Francés-Gómez, Clara; Geller, Ron; Aznar, Elena; Martínez-Máñez, Ramón(Wiley-VCH Verlag GmbH & Co. KGaA, 2023-06)
[EN] The COVID-19 pandemic, which began in 2019, has highlighted the importance of testing and tracking infected individuals as a means of mitigating the spread of the virus. In this context, the development of sensitive ...
Pla, Luis; Santiago Felipe, Sara; Tormo-Mas, María Ángeles; Pemán, Javier; Sancenón Galarza, Félix; Aznar, Elena; Martínez-Máñez, Ramón(Elsevier, 2020-10-01)
[EN] The development of new detection systems for an accurate and rapid identification of pathogens has become an essential challenge in the biomedical field. Herein a highly selective platform based on aptamer-gated nano ...
Aznar Gimeno, Elena; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Martínez Mañez, Ramón; STROEVE, PIETER; Cano, Joan; AMOROS DEL TORO, PEDRO(American Chemical Society, 2012-12-19)
This article focuses on the study of the release rate in a family of modified silica mesoporous supports. A collection of solids containing ethyl, butyl, hexyl, octyl, decyl, octadecyl, docosyl, and triacontyl groups ...
Navarro Plaza, María del Carmen(Universitat Politècnica de València, 2014-06-09)
[ES] La terapia génica es una terapia avanzada que tiene como objetivo la utilización de los ácidos nucleicos como medicamentos. Su potencial terapéutico es muy amplio y abarca prácticamente todas las patologías. Sin ...
Polo Aguado, Lorena(Universitat Politècnica de València, 2016-11-02)
[EN] Bone infection is one of the most common problems that usually appear after a prosthesis surgery. In this work, we propose the development and characterisation of a mesoporous material, which can be 3D-printed in the ...
Agostini, Alessandro; Mondragón Martínez, Laura; Pascual Vidal, Lluís; Aznar Gimeno, Elena; Coll Merino, Mª Carmen; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Soto Camino, Juan; Marcos Martínez, María Dolores; Amoros del Toro, Pedro; Costero, Ana M.; Parra, Margarita; Gil, Salvador(American Chemical Society, 2012-09-21)
[EN] An ethylene glycol-capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two-step procedure. ...
Pascual Vidal, Lluís(Universitat Politècnica de València, 2016-02-01)
An ethylene glycol capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two step procedure. ...
Ribes Momparler, Ángela(Universitat Politècnica de València, 2018-09-10)
La presente tesis doctoral titulada "Design of new nanostructured systems with applications in the field of recognition and diagnosis" está enfocada en el diseño y síntesis de nuevos materiales híbridos con función de ...
[EN] The development of new strategies to detect microRNAs (miRNAS) has become an important challenge in thebiomedical ¿eld. We report herein the use of oligonucleotide-gated silica nanoparticles for the detection ofmiRNA-145. ...
Polo Aguado, Lorena(Universitat Politècnica de València, 2018-10-30)
La presente tesis doctoral, titulada "Diseño de scaffolds inteligentes para la prevención y tratamiento de la infección ósea", se centra en el desarrollo de materiales híbridos orgánico-inorgánicos capaces de realizar una ...