[EN] A biosensing system was developed to accurately detect a single nucleotide change in the target organism genome, integrating a selective isothermal amplification and a sensitive dendron-mediated DNA hybridization assay ...

[EN] The selective and sensitive detection of single nucleotide variations is essential for early diagnosis, individualized therapy, and disease prognosis. The SARS-CoV-2 pandemic has highlighted the pressing need to develop ...

[EN] The clinical management of large-size cartilage lesions is difficult due to the limited regenerative ability of the cartilage. Different biomaterials have been used to develop tissue engineering substitutes for cartilage ...

[EN] The studied challenge is the specific detection of low-abundant genomic variants that differ by a single nucleotide from the wild type. The combination of blocked recombinase polymerase amplification (RPA) and selective ...

[EN] This study presents a useful strategy for the bioconjugation of probes for developing high-performance versatile chips applied to fast-response, low-cost DNA biosensing. We herein demonstrate that the high-density ...