[EN] Polymer ceramic composites obtained as the result of a mineralization process hold great promise for the future of tissue engineering. Simulated body fluids (SBFs) are widely used for the mineralization of polymer ...
Composite scaffolds of poly(l-lactide acid) and hydroxyapatite are of great interest in bone tissue engineering, but their mechanical properties are typically inferior to scaffolds of pure poly(l-lactide acid) due to ...
Due to the attractive properties of poly(l-lactic acid) (PLLA) for tissue engineering, the aim was to determine the growth and differentiation capacity of mesenchymal stromal cells (MSCs) in PLLA scaffolds and their potential ...
Magalhaes, Joana; Lebourg, Myriam Madeleine; Deplaine, Harmony; Gómez Ribelles, José Luís; Blanco, Francisco J.(Mary Ann Liebert, 2015-02-01)
Due to the attractive properties of poly(L-lactic acid) (PLLA) and chitosan (CHT) for tissue engineering applications, this study is aimed at analyzing the chondrogenic potential of human bone marrow-derived mesenchymal ...
Deplaine, Harmony; Acosta-Santamaría, Victor A.; Vidaurre Garayo, Ana Jesús; Gómez Ribelles, José Luís; Doblare Castellano, Manuel; Ochoa-Garrido, Ignacio; Gallego-Ferrer, Gloria(Wiley, 2014-10-15)
[EN] A poly(L-lactic acid) scaffold prepared by a combination of freeze-extraction and porogen-leaching methods was submitted
to static degradation in a phosphate-buffered saline solution at pH 7.4 and 37 C for up to 12 ...
Sanz, P.; Mora, Gonzalo; Ripalda, P.; Ferrer, G.G.; Deplaine, Harmony; Gómez Ribelles, José Luís; Prosper, Felipe; Izal, I.(Elsevier, 2012-04)
[EN] Purpose: Cartilage injuries are poorly repaired after surgery, since cartilage is a tissue with a very limited capacity to regenerate. Apart from other surgical attempts, autologous chondrocyte implantation (ACI) was ...
Acosta Santamaria, V.; Deplaine, Harmony; Mariggio, D.; Villanueva Molines, Ana Rosalía; Garcia Aznar, Jose Manuel; Gómez Ribelles, José Luís; Doblare Castellano, Manuel; Gallego-Ferrer, Gloria; Ochoa, I.(Elsevier, 2012-12-01)
The development of macroporous biodegradable polymeric materials with three-dimensional pore structure is an important research field in tissue engineering. Structural scaffolds not only provide the cells with a mechanical ...