[EN] The aim of this study was to evaluate whether mechanical stimulation helps to modulate the redifferentiation of human chondrocytes on adhesive 3D substrates. In a previous work, it was shown that chondrocytes seeded ...
A hydrogel based on interpenetrating polymer networks (IPNs) has been designed to act as a platform in an articular cartilage bioreactor for the ex vivo test of scaffolds, simulating the host tissue. Poly(2-hydroxyethyl ...
Gamboa Martínez, Tatiana Carolina; Gómez Ribelles, José Luís; Gallego-Ferrer, Gloria(SAGE Publications (UK and US), 2011-09)
A hybrid scaffold was obtained by the deposition of a thin network of submicron fibrin fibrils on the microporous walls of a macroporous poly(L-lactide) (PLLA) three-dimensional structure. The fibrin coating is homogeneous ...
Gamboa Martínez, Tatiana Carolina; García Cruz, Dunia Mercedes; Carda, Carmen; Gómez Ribelles, José Luís; Gallego-Ferrer, Gloria(Wiley, 2013-02)
The aim of this study was to develop a biocompatible monolayer substrate based on fibrin and chitosan for in vitro culture of chondrocytes. Fibrin-chitosan composite substrates combined the proved cell adhesion properties ...
[EN] Poly(L-lactic acid) (PLLA) microfibers were surface functionalized by graft photopolymerization of 2-hydroxyethyl methacrylate (HEMA) onto the fiber surface. Grafted fibers were easily dispersed in enzymatically gelling ...
Araque Monrós, María Carmen; Gamboa Martínez, Tatiana Carolina; Gil Santos, Luis; Gironés Bernabé, Sagrario; Monleón Pradas, Manuel; Más Estellés, Jorge(Wiley, 2013-11)
We present a concept for a new regenerative and resorbable prosthesis for tendon and ligament and characterize the physicomechanical and biological behavior of one of its components, a hollow braid made of poly-lactide ...
[EN] In the present study, we examined the potential of using highly porous poly(epsilon-caprolactone) (PCL)-coated hydroxyapatite (HAp) scaffold derived from cuttlefish bone for bone tissue engineering applications. The ...
Trujillo, Sara; Plazas Bonilla, Clara Eugenia; Santos, Marta Sofía; Matos, Joana M.; Gamboa Martínez, Tatiana Carolina; Perilla, Jairo Ernesto; Mano, Joao F.; Gómez Ribelles, José Luís(Springer Verlag, 2014-07)
The aim of this work is to develop polycaprolactone based porous materials with improved mechanical performance to be used in bone repair. The hybrid membranes consist in a polymeric porous material in which the pore walls ...
[EN] Short poly-l-lactic acid (PLLA) microfibers have been produced in order to disperse them into the gelatin solution and enable injection in the tissue defect prior to gel formation. Two methods for fabrication of loose ...