Majer, Eszter; Navarro Bohigues, José Antonio; Daros Arnau, Jose Antonio(Wiley-VCH Verlag, 2015-11)
Plant virus-based expression systems allow quick and efficient production of recombinant proteins in plant biofactories. Among them, a system derived from tobacco etch virus (TEV; genus potyvirus) permits coexpression of ...
[EN] Organisms have different circuitries that allow converting signal molecule levels to changes in gene expression. An important challenge in synthetic biology involves the de novo design of RNA modules enabling dynamic ...
Rodrigo Tarrega, Guillermo; Majer, Eszter; Prakash, Satya; Daros Arnau, Jose Antonio; Jaramillo, Alfonso; Poyatos, Juan F.(Biophysical Society, 2015-09-01)
[EN] The regulation of gene expression, triggered by conformational changes in RNA molecules, is widely observed in cellular systems. Here, we examine this mode of control by means of a model-based design and construction ...
Rodrigo Tarrega, Guillermo; Landrain, Thomas E.; Majer, Eszter; Daros Arnau, Jose Antonio; Jaramillo, Alfonso(Public Library of Science, 2013-08)
[EN] Small RNAs (sRNAs) can operate as regulatory agents to control protein expression by interaction with the 59 untranslated
region of the mRNA. We have developed a physicochemical framework, relying on base pair ...
Majer, Eszter(Universitat Politècnica de València, 2016-09-01)
[EN] Plant viruses are obligate intracellular parasites which were used to develop recombinant plant virus vectors to express heterologous proteins and to modify endogenous metabolic pathways of natural products in plants. ...
Rodrigo, Guillermo; Prakash, Satya; Shen, Shensi; Majer, Eszter; DAROS ARNAU, JOSE ANTONIO; Jaramillo, Alfonso(Oxford University Press, 2017-09-19)
[EN] Synthetic gene circuits allow the behavior of living cells to be reprogrammed, and non-coding small RNAs (sRNAs) are increasingly being used as programmable regulators of gene expression. However, sRNAs (natural or ...
[EN] Plants can be engineered to sustainably produce compounds of nutritional, industrial or pharmaceutical relevance. This is, however, a challenging task as extensive regulation of biosynthetic pathways often hampers ...
Majer, Eszter; Daros Arnau, Jose Antonio; Zwart, Mark Peter(MDPI, 2013-09)
[EN] Antirrhinum majus Rosea1 (Ros1) is an MYB-related transcription factor that
induces anthocyanin biosynthesis in plant tissues, and has been shown to be suitable for
visual tracking of virus infection in plants. ...