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Listar por autor "Vanacloig Pedrós, María Elena"

Mostrando ítems 1-5 de 5

Different Toxicity Mechanisms for Citrinin and Ochratoxin A Revealed by Transcriptomic Analysis in Yeast

Vanacloig-Pedrós, Elena; Proft, Markus Hans; Pascual-Ahuir Giner, María Desamparados (MDPI AG, 2016-09-22)

[EN] Citrinin (CIT) and ochratoxin A (OTA) are important mycotoxins, which frequently co-contaminate foodstuff. In order to assess the toxicologic threat posed by the two mycotoxins separately or in combination, their ...
Dose dependent gene expression is dynamically modulated by the history, physiology and age of yeast cells

Pascual-Ahuir Giner, María Desamparados; González-Cantó, Eva; Juyoux, Pauline; Pable, Julia; Poveda-Huertes, Daniel; Saiz-Balbastre Sandra; Squeo, Sonia; Ureña-Marco, Alvaro; Vanacloig-Pedrós, Elena; Zaragoza-Infante, Laura; Proft, Markus Hans (Elsevier, 2019-04)

[EN] Cells respond to external stimuli with transient gene expression changes in order to adapt to environmental alterations. However, the dose response profile of gene induction upon a given stress depends on many intrinsic ...
Estrategias de defensa a estrés químico en Saccharomyces cerevisiae: regulación genética del transporte multidroga y mecanismos de detoxificación

Vanacloig Pedrós, María Elena (Universitat Politècnica de València, 2018-11-05)

En la presente tesis se han estudiado los distintos mecanismos de toxicidad de las micotoxinas citrinina y ocratoxina A y la respuesta adaptativa a xenobióticos en el modelo de levadura Saccharomyces cerevisiae, concretamente ...
Live-cell assays reveal selectivity and sensitivity of the multidrug response in budding yeast

Vanacloig-Pedrós, Mª Elena; Lozano-Pérez, Carlos; Alarcon, B.; Pascual-Ahuir Giner, María Desamparados; Proft, Markus Hans (American Society for Biochemistry and Molecular Biology, 2019-08-30)

[EN] Pleiotropic drug resistance arises by the enhanced extrusion of bioactive molecules and is present in a wide range of organisms, ranging from fungi to human cells. A key feature of this adaptation is the sensitive ...
Toxicity Mechanisms of the Food Contaminant Citrinin: Application of a Quantitative Yeast Model

Pascual-Ahuir Giner, María Desamparados; Vanacloig Pedrós, María Elena; Proft, Markus Hans (MDPI AG, 2014-05)

Mycotoxins are important food contaminants and a serious threat for human nutrition. However, in many cases the mechanisms of toxicity for this diverse group of metabolites are poorly understood. Here we apply live cell ...