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Listar por autor "Bonancía Roca, Paula"

Mostrando ítems 1-8 de 8

Drug/protein interactions studied by time-resolved fluorescence spectroscopy

Gustavsson, Thomas; Markovitsi, Dimitra; Vayá Pérez, Ignacio; Bonancía Roca, Paula; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (Society of Photo-optical Instrumentation Engineers (SPIE), 2014)

[EN] We report here on a recent time-resolved fluorescence study [1] of the interaction between flurbiprofen (FBP), a chiral non-steroidal anti-inflammatory drug, and human serum albumin (HSA), the main transport protein ...
Especies transitorias en sistemas bioorgánicos modelo conteniendo cromóforos de tipo bifenilo, naftaleno o benzofenona

Bonancía Roca, Paula (Universitat Politècnica de València, 2013-03-07)

La espectroscopía de absorción transitoria ha resultado ser una herramienta útil para investigar la formación y desaparición de estados excitados singlete formados por aniquilación triplete-triplete, tras sensibilización. ...
Excited state interactions between flurbiprofen and tryptophan in drug-protein complexes and in model dyads. Fluorescence studies from the femtosecond to the nanosecond time domains

Vayá Pérez, Ignacio; Bonancía Roca, Paula; Jiménez Molero, María Consuelo; Markovitsi, Dimitra; Gustavsson, Thomas; Miranda Alonso, Miguel Ángel (Royal Society of Chemistry, 2013)

We report here on the interaction dynamics between flurbiprofen (FBP) and tryptophan (Trp) covalently linked in model dyads and in a complex of FBP with human serum albumin (HSA) probed by time-resolved fluorescence ...
Excited-state interactions in diastereomeric flurbiprofen-thymine dyads

Bonancía Roca, Paula; Vayá Pérez, Ignacio; Climent Olmedo, María José; Gustavsson, Thomas; Markovitsi, Dimitra; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2012-09-06)

Excited-state interactions between (S)- or (R) fluorescence (S)- or (R)-FBP) and thymidine (dThd) covalently linked in dyads 1 or 2 have been investigated. In both dyads, the only emitting species is (FBP)-F-1*, but with ...
Intraprotein formation of a long wavelength absorbing complex and inhibition of excited state deprotonation in a chiral hydroxybiphenyl

Bonancía Roca, Paula; Vayá Pérez, Ignacio; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2012-12-27)

The two enantiomers of 2-(2-hydroxybiphenyl-4-yl)propanoic acid ((S)- and (R)-BPOH) have been selected as probes for human serum albumin (HSA). Photophysical characterization in the absence of protein led to emission maxima, ...
Stereodifferentiation in the intramolecular singlet excited state quenching of hydroxybiphenyl-tryptophan dyads

Bonancía Roca, Paula; Vayá Pérez, Ignacio; Markovitsi, Dimitra; Gustavsson, Thomas; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (Royal Society of Chemistry, 2013)

The photochemical processes occurring in diastereomeric dyads (S, S)-1 and (S, R)-1, prepared by conjugation of (S)-2-(2-hydroxy-1,1'-biphenyl-4-yl) propanoic acid ((S)-BPOH) with (S)- and (R)-Trp, have been investigated. ...
Transient absorption spectroscopy detection of sensitized delayed fluorescence in chiral benzophenone/naphthalene systems

Bonancía Roca, Paula; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (Elsevier, 2011-10-17)

Transient absorption spectroscopy has proven to be a powerful tool to investigate the formation and decay of excited singlet states upon triplet–triplet annihilation, following T–T energy transfer from a selectively excited ...
Triplet excited state behavior of naphthalene-based pseudopeptides in the presence of energy donors

Bonancía Roca, Paula; Vigara, Laura; Galindo, Francisco; Luis, Santiago V.; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2012-08-23)

In this work, the triplet state behavior of naphthalene-based pseudopeptides with amide-based macrocyclic or lateral chain substructures has been investigated in the presence of benzophenone and/or biphenyl, as suitable ...