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Characterization of the activity and selectivity profile of the MCL1-BOK interaction inhibitors

Caurín Perpiñá, Víctor (Universitat Politècnica de València, 2022-07-28)

[ES] La familia de proteínas BCL2 (B-cell lymphoma 2) regula la permeabilización de la membrana mitocondrial externa (MOM) durante el proceso de muerte celular por apoptosis. Las proteínas BCL2 constituyen una familia de ...
Nanodevices for the Efficient Codelivery of CRISPR-Cas9 Editing Machinery and an Entrapped Cargo: A Proposal for Dual Anti-Inflammatory Therapy

García-Fernández, Alba; Vivo-Llorca, Gema; Sancho, Mónica; García-Jareño, Alicia Belén; Ramírez-Jiménez, Laura; Barber-Cano, Eloísa; Murguía, Jose R.; Orzaez, Mar; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (The Royal Society of Chemistry, 2022-07)

[EN] In this article, we report one of the few examples of nanoparticles capable of simultaneously delivering CRISPR-Cas9 gene-editing machinery and releasing drugs for one-shot treatments. Considering the complexity of ...

Mostrando ítems 1-2 de 2