Nardi, Giacomo; Marín García, Mª Luisa; de Souza, Pierre A.; Lhiaubet, Virginie Lyria; Miranda Alonso, Miguel Ángel(The Royal Society of Chemistry, 2014)
[EN] The photochemical properties of itraconazole (1), a broad-spectrum antifungal agent, have been investigated in connection with reported skin photosensitivity disorders. Steady state photolysis, fluorescence and ...
Nardi, Giacomo(Universitat Politècnica de València, 2015-03-31)
Photosensitizing effects of xenobiotics are of increasing concern in public health
since modern lifestyle often associates sunlight exposure with the presence of chemical
substances in the skin. An important number of ...
Nardi, Giacomo; Lhiaubet, Virginie Lyria; Miranda Alonso, Miguel Ángel(American Chemical Society, 2014-11)
[EN] Imatinib (IMT) is a promising tyrosine kinase inhibitor used in the treatment of some types of human cancer. It constitutes a successful example of rational drug design based on the optimization of the chemical structure ...
Nardi, Giacomo; Lhiaubet, Virginie Lyria; Leandro García, Paula; Miranda Alonso, Miguel Ángel(American Chemical Society, 2011)
In this work, rosuvastatin has been used to gain insight into the molecular basis of statin photosensitization. This lipid-lowering drug, also known as ¿superstatin¿, contains a 2-vinylbiphenyl-like moiety and has been ...
Nardi, Giacomo; Manet, Ilse; Monti, Sandra; Miranda Alonso, Miguel Ángel; Lhiaubet-Vallet, Virginie(Elsevier, 2014-12)
For many biological and biomedical studies, it is essential to detect the production of O-1(2) and quantify its production yield. Among the available methods, detection of the characteristic 1270-nm phosphorescence of ...
Nardi, Giacomo; Lineros-Rosa, Mauricio; Palumbo, Fabrizio; Miranda Alonso, Miguel Ángel; Lhiaubet, Virginie Lyria(Elsevier, 2021-01-15)
[EN] Dipicolinic acid (DPA), present in large amount in bacterial spores, has been proposed to act as an endogenous photosensitizer in spore photoproduct formation. The proposed mechanism involves a triplet-triplet energy ...