[EN] The self-association of fluoroquinolones (FQ) in water would play a relevant role in their translocations across lipid membranes. Triplet excited states of these drugs have been shown as reporters of FQ self-association ...
[EN] Phototoxic effects of 6,8 dihalogenated quinolones confers to this type of molecules a potential property as photochemotherapeutic agents. Two photodehalogenation processes seem to be involved in the remarkable ...
Valero Muñoz, María del Carmen(Universitat Politècnica de València, 2018-01-09)
[ES] En este proyecto se han sintetizado tres nuevos fotocatalizadores todos ellos formados por
dióxido de titanio sobre microesferas de sílice, y a dos de estos fotocatalizadores se les han
depositado nanopartículas de ...
Soldevila Serrano, Sonia(Universitat Politècnica de València, 2016-01-07)
[EN] Fluoroquinolones (FQ) are the antibiotics most used nowadays. Some of its derivatives have anti-tumor activity. Both in vitro and in vivo studies have shown anti-cancer property of these compounds. Its mechanism of ...
Soldevila Serrano, Sonia; Bosca Mayans, Francisco(American Chemical Society, 2012)
The nature of stabilized aryl cations generated from photodehalogenations of fluoroquinolones in aqueous media has been studied by comparing the photophysical and photochemical behavior of lomefloxacin (LFX) and its ...
The mechanism responsible for the remarkable photomutagenicity of fluoroquinolone (FQ) antibiotics remains unknown. For this reason, it was considered worthwhile to study in detail the interactions between DNA and a ...
Roig Ferrer, Ángela(Universitat Politècnica de València, 2022-12-28)
[ES] El paracetamol (N-4-hidroxifenil-acetamida) es uno de los fármacos más utilizado como analgésico y antipirético a nivel mundial, ya que se encuentra disponible sin necesidad de prescripción médica. Durante la ...
Martínez Moreno, Natalia(Universitat Politècnica de València, 2018-09-26)
[ES] En este proyecto se han sintetizado nuevos fotocatalizadores para estudiar la
fotodegradación de contaminantes representativos de aguas residuales. Los fotocatalizadores
que se sintetizarán estarán formados por ...
Cuquerella Alabort, Maria Consuelo; Andreu Ros, María Inmaculada; Soldevila Serrano, Sonia; Bosca Mayans, Francisco(American Chemical Society, 2012-05-31)
Generation of triplet eximers of 6-fluoro-7-piperazinylquinolone-3-carboxylic acids (FQs) have been detected in aqueous media using laser flash photolysis (LFP). These transient species (SS) are generated by self-quenching ...
Soldevila Serrano, Sonia; Cuquerella Alabort, Maria Consuelo; Bosca Mayans, Francisco(American Chemical Society, 2014-04)
Although the phototoxic and photoallergic properties of fluoroquinolone antibiotics (FQ) are remarkable, the mechanisms involved in these processes are not completely understood. For this reason, it is considered worthwhile ...