[EN] INTRODUCTIONThe three clinical variants of frontotemporal dementia (behavioral variant [bvFTD], semantic dementia, and progressive non-fluent aphasia [PNFA]) are likely to develop over decades, from the preclinical ...
Kamraoui, Reda Abdellah; Ta, Vinh-Thong; Tourdias, Thomas; Mansencal, Boris; Manjón Herrera, José Vicente; Coupé, Pierrick(Elsevier, 2022-02)
[EN] Recently, segmentation methods based on Convolutional Neural Networks (CNNs) showed promising per-formance in automatic Multiple Sclerosis (MS) lesions segmentation. These techniques have even out-performed human ...
[EN] In this article, we present an innovative MRI-based method for Alzheimer disease (AD) detection and mild cognitive impairment (MCI) prognostic, using lifespan trajectories of brain structures. After a full screening ...
[EN] Numerous studies have proposed biomarkers based on magnetic resonance imaging (MRI) to detect and predict the risk of evolution toward Alzheimer's disease (AD). Most of these methods have focused on the hippocampus, ...
[EN] Background: Whether hippocampal subfields are differentially vulnerable at the earliest stages of multiple sclerosis (MS) and how this impacts memory performance is a current topic of debate.
Method: We prospectively ...
Planche, Vincent; Manjón Herrera, José Vicente; Mansecal, Boris; Lanuza, Enrique; Tourdias, Thomas; Catheline, Gwenaelle; Coupé, Pierrick(Oxford University Press, 2022-05-02)
[EN] The chronological progression of brain atrophy over decades, from pre-symptomatic to dementia stages, has never been formally depicted in Alzheimer's disease. This is mainly due to the lack of cohorts with long enough ...