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Listar por autor "Sardanyes Cayuela, Jose"

Mostrando ítems 1-7 de 7

Complex dynamics of defective interfering baculoviruses during serial passage in insect cells

Zwart, Mark Peter; Pijlman, G.P.; Sardanyes Cayuela, Jose; Duarte, J; Januario, C; Elena Fito, Santiago Fco (Springer Verlag (Germany), 2013-03)

Defective interfering (DI) viruses are thought to cause oscillations in virus levels, known as the 'Von Magnus effect'. Interference by DI viruses has been proposed to underlie these dynamics, although experimental tests ...
Differences in accumulation and virulence determine the outcome of competition during Tobacco etch virus coinfection

Lafforgue, Guillaume; Sardanyes Cayuela, Jose; Elena Fito, Santiago Fco (Public Library of Science, 2011-03-15)

[EN] Understanding the evolution of virulence for RNA viruses is essential for developing appropriate control strategies. Although it has been usually assumed that virulence is a consequence of within-host replication of ...
Dynamics of a plant RNA virus intracellular accumulation: stamping machine versus geometric replication

Martinez, Fernando; Sardanyes Cayuela, Jose; Elena Fito, Santiago Fco; Daros Arnau, Jose Antonio (Genetics Society of America, 2011-07)

[EN] The tremendous evolutionary potential of RNA viruses allows them to thrive despite host defense mechanisms and endows them with properties such as emergence, host switching, and virulence. The frequency of mutant ...
Dynamics of alternative modes of RNA replication for positive-sense RNA viruses

Sardanyes Cayuela, Jose; Martinez, Fernando; Daros Arnau, Jose Antonio; Elena Fito, Santiago Fco (Royal Society, The, 2012-04-07)

[EN] We propose and study nonlinear mathematical models describing the intracellular time dynamics of viral RNA accumulation for positive-sense single-stranded RNA viruses. Our models consider different replication modes ...
Predicting the Stability of Homologous Gene Duplications in a Plant RNA Virus

Willemsen, Anouk; Zwart, Mark Peter; Higueras, Pablo; Sardanyes Cayuela, Jose; Elena Fito, Santiago Fco (Oxford University Press (OUP), 2016-09)

One of the striking features of many eukaryotes is the apparent amount of redundancy in coding and non-coding elements of their genomes. Despite the possible evolutionary advantages, there are fewer examples of redundant ...
Quasispecies spatial models for RNA viruses with different replication modes and infection strategies

Sardanyes Cayuela, Jose; Elena Fito, Santiago Fco (Public Library of Science, 2011)

[EN] Empirical observations and theoretical studies suggest that viruses may use different replication strategies to amplify their genomes, which impact the dynamics of mutation accumulation in viral populations and ...
Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations

Sardanyes Cayuela, Jose; Simó, Carles; Martínez, Regina; Solé, Ricard V.; Elena Fito, Santiago Fco (Nature Publishing Group, 2014-04-09)

[EN] The distribution of mutational fitness effects (DMFE) is crucial to the evolutionary fate of quasispecies. In this article we analyze the effect of the DMFE on the dynamics of a large quasispecies by means of a ...