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Listar por autor "Ultimo, Amelia"

Mostrando ítems 1-5 de 5

Desarrollo de nanopartículas mesoporosas de sílice para el tratamiento de cancer de mama

Garrido Cano, Iris (Universitat Politècnica de València, 2016-09-02)

[EN] The aim of this project is to develop nanodispositives based on silica mesoporous nanoparticles for triple negative breast cancer treatment. Those will be directed against the cancer stem cell subpopulation for ...
Design and development of new bio-gated nanodevices for targeted controlled drug release

Ultimo, Amelia (Universitat Politècnica de València, 2019-10-28)

[ES] La presente tesis doctoral, titulada "Diseño y desarrollo de nuevos nanodispositivos con puertas biomoleculares para la liberación dirigida y controlada de fármacos", está centrada en el diseño, síntesis, caracterización ...
High-Capacity Mesoporous Silica Nanocarriers of siRNA for Applications in Retinal Delivery

Ultimo, Amelia; Orzáez, Mar; Santos-Martinez, Maria J.; Martínez-Máñez, Ramón; Marcos Martínez, María Dolores; Sancenón Galarza, Félix; Ruiz-Hernández, Eduardo (MDPI AG, 2023-02)

[EN] The main cause of subretinal neovascularisation in wet age-related macular degeneration (AMD) is an abnormal expression in the retinal pigment epithelium (RPE) of the vascular endothelial growth factor (VEGF). Current ...
In Situ-Forming Gels Loaded with Stimuli-Responsive Gated Mesoporous Silica Nanoparticles for Local Sustained Drug Delivery

De La Torre, Cristina; Coll, Carmen; Ultimo, Amelia; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Ruiz-Hernández, Eduardo (MDPI AG, 2023-04)

[EN] A novel combination of in situ-forming hydrogels of hyaluronic acid with gated mesoporous materials was developed to design depots for local sustained release of chemotherapeutics. The depot consists of a hyaluronic-based ...
Nanoparticle-cell-nanoparticle communication by stigmergy to enhance poly(I:C) induced apoptosis in cancer cells

Ultimo, Amelia; De La Torre-Paredes, Cristina; Giménez, Cristina; Aznar, Elena; Coll, Carmen; Marcos Martínez, María Dolores; Murguía, Jose R.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (The Royal Society of Chemistry, 2020-07-07)

[EN] Nanoparticle-cell-nanoparticle communication by stigmergy was demonstrated using two capped nanodevices. The first community of nanoparticles (i.e.S(RA)(IFN)) is loaded with 9-cis-retinoic acid and capped with ...