Goiriz, Lucas; Ruiz, Raúl; Garibo-i-Orts, Óscar; Conejero, J. Alberto; Rodrigo Tarrega, Guillermo(Proceedings of the National Academy of Sciences, 2023-07-25)
[EN] The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans has been monitored at an unprecedented level due to the public health crisis, yet the stochastic dynamics underlying such a process ...
Pérez Ruiz, Raúl(Universitat Politècnica de València, 2008-05-07)
La ciclorreversión (CR) oxidativa ó reductiva de oxetanos por transferencia electrónica fotoinducida (TEF), no ha sido estudiada en profundidad, a pesar de que este proceso ha despertado un gran interés en la última década ...
Pérez Ruiz, Raúl; Griesbeck, Axel G.; Sampedro, Diego(Elsevier, 2012-07-22)
[EN] The mechanism of the fluoride anion recognition by an urea phthalimide chemosensor has been studied in detail by means of CASPT2//CASSCF calculations. Computational data are in well-agreement with changes in the ...
[EN] The novel respiratory virus SARS-CoV-2 is rapidly
evolving across the world with the potential of increasing its
transmission and the induced disease. Here, we applied the
CRISPR-Cas12a system to detect, without ...
Soldevilla, Alberto; Pérez Ruiz, Raúl; Diaz Miara, Yrene; Griesbeck, Axel(Royal Society of Chemistry, 2010)
The fluorescence of caged phthalimide-serine couples 2 and 4 is up/down modulated by decarboxylative photorelease with fluorescence decrease (2) vs. moderate fluorescence increase (4) serving as reporter function.
Domingo, Luis R.; Pérez Ruiz, Raúl; Arguello, Juan Elias; Miranda Alonso, Miguel Ángel(American Chemical Society, 2011-06)
The molecular mechanism of the cycloreversion (CR) of thietane radical cations has been analyzed in detail at the UB3LYP/6-31G* level of theory. Results have shown that the process takes place via a stepwise mechanism ...
[EN] Viral infections in plants threaten food security. Thus, simple and effective methods for virus detection are required to adopt early measures that can prevent virus spread. However, current methods based on the ...
[EN] Recurrent disease outbreaks caused by different viruses, including the novel respiratory virus SARS-CoV-2, are challenging our society at a global scale; so versatile virus detection methods would enable a calculated ...
Pérez Ruiz, Raúl; Alonso Ruiz, Rafael; Nuin Plá, Neus Edurne; Andreu Ros, María Inmaculada; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2011-04-21)
[EN] Three drugs containing the naphthalene (NP) chromophore, namely, naproxen (NPX), propranolol (PPN), and cinacalcet (CIN), but with different affinities toward serum albumins (SAs) and alpha-1-acid glycoproteins (AAGs) ...
[EN] RNA recognition motifs (RRMs) are widespread RNA-binding protein domains in eukaryotes, which represent promising synthetic biology tools due to their compact structure and efficient activity. Yet, their use in ...
Limones Herrero, Daniel; Pérez Ruiz, Raúl; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(Wiley, 2014-10)
Cyamemazine (CMZ) is a neuroleptic drug that mediates cutaneous phototoxicity in humans. Here, the photobehavior of CMZ has been examined within (1)-acid glycoproteins, - and -cyclodextrins and SDS micelles. In all these ...
Pérez Ruiz, Raúl; Sáez Cases, José Antonio; Domingo, Luis R.; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(Royal Society of Chemistry, 2012)
The radical anions of azetidin-2-ones, generated by UV-irradiation in the presence of triethylamine, undergo ring-splitting via N-C4 or C3-C4 bond breaking, leading to open-chain amides. This reactivity diverges from that ...