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Listar por autor "Gallego Bartolomé, Javier"

Mostrando ítems 1-20 de 25

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A DNA methylation reader complex that enhances gene transcription

Harris, C. Jake; Scheibe, Marion; Wongpalee, Somsakul Pop; Liu, Wanlu; Cornett, Evan M.; Vaughan, Robert M.; Li, Xueqin; Chen, Wei; Xue, Yan; Zhong, Zhenhui; Yen, Linda; Barshop, William D.; Rayatpisheh, Shima; Gallego Bartolomé, Javier; Groth, Martin (American Association for the Advancement of Science (AAAS), 2018-12-07)

[EN] DNA methylation generally functions as a repressive transcriptional signal, but it is also known to activate gene expression. In either case, the downstream factors remain largely unknown. By using comparative ...
A hormonal regulatory module that provides flexibility to tropic responses

Gallego Bartolomé, Javier; Kami, C; Fankhauser, Christian; Alabadí Diego, David; Blazquez Rodriguez, Miguel Angel (American Society of Plant Biologists, 2011-08)

[EN] Plants orient their growth depending on directional stimuli such as light and gravity, in a process known as tropic response. Tropisms result from asymmetrical accumulation of auxin across the responding organ relative ...
A One Precursor One siRNA Model for Pol IV-Dependent siRNA Biogenesis.

Zhai, Jixian; Bischof, Sylvain; Wang, Haifeng; Feng, Suhua; Lee, Tzuu-Fen; Teng, Chong; Chen, Xinyuan; Park, Soo Young; Liu, Linshan; Gallego Bartolomé, Javier; Liu, Wanlu; Henderson, Ian R; Meyers, Blake C.; Ausin, Israel; Jacobsen, Steven E. (Elsevier, 2015-10-08)

[EN] RNA-directed DNA methylation in Arabidopsis thaliana is driven by the plant-specific RNA Polymerase IV (Pol IV). It has been assumed that a Pol IV transcript can give rise to multiple 24-nt small interfering RNAs ...
Co-targeting RNA Polymerases IV and V Promotes Efficient De Novo DNA Methylation in Arabidopsis

Gallego Bartolomé, Javier; Liu, Wanlu; Kuo, Peggy Hsuanyu; Feng, Suhua; Ghoshal, Basudev; Gardiner, Jason; Zhao, Jenny Miao-Chi; Park, Soo Young; Chory, Joanne; Jacobsen, Steven E. (Elsevier, 2019-02-21)

[EN] The RNA-directed DNA methylation (RdDM) pathway in plants controls gene expression via cytosine DNA methylation. The ability to manipulate RdDM would shed light on the mechanisms and applications of DNA methylation ...
Comprehensive identification of SWI/SNF complex subunits underpins deep eukaryotic ancestry and reveals new plant components.

Hernández-García, Jorge; Diego-Martín, Borja; Kuo, Peggy Hsuanyu; Jami-Alahmadi, Yasaman; Vashisht, Ajay A.; Wohlschlegel, James; Jacobsen, Steven E.; BLAZQUEZ RODRIGUEZ, MIGUEL ANGEL; Gallego-Bartolomé, Javier (Springer Nature, 2022-06-06)

[EN] Over millions of years, eukaryotes evolved from unicellular to multicellular organisms with increasingly complex genomes and sophisticated gene expression networks. Consequently, chromatin regulators evolved to support ...
CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation

Wongpalee, Somsakul Pop; Liu, Shiheng; Gallego Bartolomé, Javier; Leitner, Alexander; Aebersold, Ruedi; Liu, Wanlu; Yen, Linda; Nohales, Maria A.; Kuo, Peggy Hsuanyu; Vashisht, Ajay A.; Wohlschlegel, James A.; Feng, Suhua; Kay, Steve A.; Zhou, Z. Hong; Jacobsen, Steven E. (Nature Publishing Group, 2019-09-02)

[EN] Transcription by RNA polymerase V (Pol V) in plants is required for RNA-directed DNA methylation, leading to transcriptional gene silencing. Global chromatin association of Pol V requires components of the DDR complex ...
DELLA -induced early transcriptional changes during etiolated development in Arabidopsis thaliana

Gallego Bartolomé, Javier; Alabadí Diego, David; Blazquez Rodriguez, Miguel Angel (Public Library of Science, 2011)

The hormones gibberellins (GAs) control a wide variety of processes in plants, including stress and developmental responses. This task largely relies on the activity of the DELLA proteins, nuclear-localized transcriptional ...
Della protein function during differential growth processes in arabidopsis

Gallego Bartolomé, Javier (Universitat Politècnica de València, 2011-08-01)

The plant hormones gibberellins (GAs) regulate multiple processes of plant development. Most of this regulation occurs at the transcriptional level, through the activity of the DELLAs, which are nuclear-localized proteins ...
DNA methylation in plants: mechanisms and tools for targeted manipulation.

Gallego Bartolomé, Javier (Blackwell Publishing, 2020-07)

[EN] DNA methylation is an epigenetic mark that regulates multiple processes, such as gene expression and genome stability. Mutants and pharmacological treatments have been instrumental in the study of this mark in plants, ...
DNA methylome of the 20-gigabase Norway spruce genome.

Ausin, Israel; Feng, Suhua; Yu, Chaowei; Liu, Wanlu; Kuo, Hsuan Yu; Jacobsen, Elise L.; Zhai, Jixian; Gallego Bartolomé, Javier; Wang, Lin; Egertsdotter, Ulrika; Street, Nathaniel R.; Jacobsen, Steven E.; Wang, Haifeng (Proceedings of the National Academy of Sciences, 2016-12-13)

[EN] DNA methylation plays important roles in many biological processes, such as silencing of transposable elements, imprinting, and regulating gene expression. Many studies of DNA methylation have shown its essential roles ...
Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase

Liu, Wanlu; Gallego Bartolomé, Javier; Zhou, Yuxing; Zhong, Zhenhui; Wang, Ming; Wongpalee, Somsakul Pop; Gardiner, Jason; Feng, Suhua; Kuo, Peggy Hsuanyu; Jacobsen, Steven E. (Nature Publishing Group, 2021-05-25)

[EN] The ability to target epigenetic marks like DNA methylation to specific loci is important in both basic research and in crop plant engineering. However, heritability of targeted DNA methylation, how it impacts gene ...
Gibberellins modulate light signalling pathways to prevent seedling de-etiolation in darkness.

Alabadí, David; Gallego-Bartolomé, Javier; Orlando, Leonardo; García-Cárcel, Laura; Rubio, Vicente; Martínez, Cristina; Frigerio, Martín; Iglesias-Pedraz, Juan Manuel; Espinosa, Ana; Wang Deng, Xing; BLAZQUEZ RODRIGUEZ, MIGUEL ANGEL (Blackwell Publishing, 2008-01)

[EN] In many plants, photomorphogenesis is the default developmental program after seed germination, and provides the key features that allow adaptation to light. This program is actively repressed if germination occurs ...
Hierarchical action and inhibition of plant Dicer-like proteins in antiviral defense

Deleris, Angelique; Gallego Bartolomé, Javier; Bao, Jinsong; Kasschau, Kristin D.; Carrinton, James C.; Voinnet, Olivier (American Association for the Advancement of Science (AAAS), 2006-07-07)

[EN] The mechanisms underlying induction and suppression of RNA silencing in the ongoing plant-virus arms race are poorly understood. We show here that virus-derived small RNAs produced by Arabidopsis Dicer-like 4 (DCL4) ...
Hierarchy of hormone action controlling apical hook development in Arabidopsis

Gallego Bartolomé, Javier; Arana, María Verónica; Vandenbussche, Filip; Zadnikova, P.; Minguet, E.G.; Guardiola Herraez, Vicente Gerardo; Van der Straeten, Dominique; Benková, Eva; Alabadí Diego, David; Blazquez Rodriguez, Miguel Angel (Wiley, 2011-08)

[EN] The apical hook develops in the upper part of the hypocotyl when seeds buried in the soil germinate, and serves to protect cotyledons and the shoot apical meristem from possible damage caused by pushing through the ...
Hormonal regulation of temperature-induced growth in Arabidopsis

Stavang, Jon A.; Gallego-Bartolomé, J.; Gómez Jiménez, Maria Dolores; Yoshida, Shigeo; Asami, Tadao; Olsen, Jorunn E.; García-Martínez, José L.; ALABADÍ DIEGO, DAVID; BLAZQUEZ RODRIGUEZ, MIGUEL ANGEL (Blackwell Publishing, 2009-11)

[EN] Successful plant survival depends upon the proper integration of information from the environment with endogenous cues to regulate growth and development. We have investigated the interplay between ambient temperature ...
Identification of Multiple Proteins Coupling Transcriptional Gene Silencing to Genome Stability in Arabidopsis thaliana

Hale, Christopher J.; Potok, Magdalena E.; Lopez, Jennifer; Do, Truman; Liu, Ao; Gallego Bartolomé, Javier; Michaels, Scott D.; Jacobsen, Steven E. (Public Library of Science, 2016-06)

[EN] Eukaryotic genomes are regulated by epigenetic marks that act to modulate transcriptional control as well as to regulate DNA replication and repair. In Arabidopsis thaliana, mutation of the ATXR5 and ATXR6 histone ...
Mind the gap: Epigenetic regulation of chromatin accessibility in plants

Candela-Ferre, Joan; Diego-Martín, Borja; Pérez-Alemany, Jaime; Gallego-Bartolomé, Javier (American Society of Plant Biologists, 2024-03-29)

[EN] Chromatin plays a crucial role in genome compaction and is fundamental for regulating multiple nuclear processes. Nucleosomes, the basic building blocks of chromatin, are central in regulating these processes, determining ...
Molecular mechanism for the interaction between gibberellin and brassinosteroid signaling pathways in Arabidopsis

Gallego Bartolomé, Javier; Minguet, Eugenio G.; Grau Enguix, Federico; Abbas, Mohamad; Locascio, Antonella Anna Maria; Thomas, Stephen G.; Alabadí Diego, David; Blazquez Rodriguez, Miguel Angel (National Academy of Sciences, 2012-07-14)

[EN] Plant development is modulated by the convergence of multiple environmental and endogenous signals, and the mechanisms that allow the integration of different signaling pathways is currently being unveiled. A paradigmatic ...
Molecular mechanism of action of plant DRM de novo DNA methyltransferases

Zhong, Xuehua; Du, Jiamu; Hale, Christopher J; Gallego Bartolomé, Javier; Feng, Suhua; Vashisht, Ajay A.; Chory, Joanne; Wohlschlegel, James A.; Patel, Dinshaw J.; Jacobsen, Steven E. (Elsevier, 2014-05-26)

[EN] DNA methylation is a conserved epigenetic generegulation mechanism. DOMAINS REARRANGED METHYLTRANSFERASE (DRM) is a key de novo methyltransferase in plants, but how DRM acts mechanistically is poorly understood. ...
Polarization of PIN3-dependent auxin transport for hypocotyl gravitropic response in Arabidopsis thaliana

Rakusova, Hana; Gallego Bartolomé, Javier; Vanstraelen, M.; Robert, H.S; Alabadí Diego, David; Blazquez Rodriguez, Miguel Angel; Benková, Eva; Friml, J (Wiley, 2011-09)

[EN] Gravitropism aligns plant growth with gravity. It involves gravity perception and the asymmetric distribution of the phytohormone auxin. Here we provide insights into the mechanism for hypocotyl gravitropic growth. ...