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Listar por autor "Giménez Romero, David"

Mostrando ítems 1-12 de 12

An all-in-one point-of-care testing device for multiplexed detection of respiratory infections

Teixeira, William; Pallás-Tamarit, Yeray; Juste-Dolz, Augusto Miguel; Sena-Torralba, Amadeo; Gozalbo-Rovira, Roberto; Rodríguez-Díaz, Jesús; Navarro, David; Carrascosa Rubio, Javier; Giménez-Romero, David; Maquieira Catala, Angel; Morais, Sergi (Elsevier, 2022-10-01)

[EN] The impact of the COVID-19 pandemic has reinforced the need for rapid, cost-effective, and reliable point-of-care testing (POCT) devices for massive population screening. The co-circulation of SARS-CoV-2 with several ...
Dual-Polarization Interferometry: A Novel Technique To Light up the Nanomolecular World

Escorihuela Fuentes, Jorge; González Martínez, Miguel Ángel; López-Paz, José Luis; Puchades, Rosa; Maquieira Catala, Ángel; Giménez Romero, David (American Chemical Society, 2015-01-14)

[EN] The challenging lecture given in 1959 by physicist and Nobel Prize awarded R. P. Feynman: “There's plenty of room at the bottom” is considered to be the starting point for nanotechnology. With this peculiar title, ...
Elucidation of Carbohydrate Molecular Interaction Mechanism of Recombinant and Native ArtinM

Giménez Romero, David; Roberto Bueno, Paulo; Pesquero, Naira C.; Monzó, Isidro S.; Puchades, Rosa; Maquieira Catala, Ángel (American Chemical Society, 2013-07-18)

[EN] The quartz crystal microbalance (QCM) technique has been applied for monitoring the biorecognition of ArtinM lectins at low horseradish peroxidase glycoprotein (HRP) concentrations, using a simple kinetic model based ...
Enzyme Inhibition Microassays on Blu-Ray Disks for Drug Discovery

Sancho-Fornes, Gabriel; Peris Chanzá, Ernesto José; Giménez-Romero, David; Morais, Sergi; Maquieira Catala, Angel (American Chemical Society, 2019)

[EN] An enzyme inhibition-based assay for drug discovery developed by microarraing on Blu-ray disks is presented. As a proof-of-concept, the system screens a selected molecule library of potential chemical inhibitors ...
Flow injection biamperometric determination of chloramine-T in environmental, pharmaceutical and veterinary samples

Catalá-Icardo, Mónica; Giménez-Romero, D.; García Mateo, J.V.; Martínez Calatayud, J. (Elsevier, 2000-02-29)

[EN] A flow injection assembly for the determination of chloramine-T is proposed. The sample (213 mu l) is inserted into the carrier, de-ionized water flowing at 4.1 mi min(-1). This carrier merges with a mixture of potassium ...
Identification of high-affinity phage-displayed VH fragments by use of a quartz crystal microbalance with dissipation monitoring

Gómez-Arribas, Lidia N.; Juste-Dolz, Augusto Miguel; Peltomaa, Riikka; Giménez-Romero, David; Morais, Sergi; Barderas, Rodrigo; Cuadrado, Carmen; Maquieira Catala, Angel; Benito-Peña, Elena; Moreno-Bondi, María C. (Elsevier, 2021-08-01)

[EN] Phage display has become a powerful tool for antibody discovery in a wide variety of fields. This technology allows specific binders for a given antigen to be selected from combinatorial libraries. A key step in the ...
INSEL: An in silico method for optimizing and exploring biorecognition assays

Avella-Oliver, Miquel; Giménez Romero, David; Morais, Sergi; González Martínez, Miguel Ángel; Bueno, Paulo Roberto; Puchades, Rosa; Maquieira Catala, Ángel (Royal Society of Chemistry, 2013)

[EN] A practical in silico method for optimizing and exploring biointeraction-based events is developed.
Label-free piezoelectric biosensor for prognosis and diagnosis of Systemic Lupus Erythematosus

do Nascimento, Noelle M.; Juste-Dolz, Augusto; Grau-García, Elena; Roman-Ivorra, Jose A.; Puchades, Rosa; Maquieira Catala, Angel; Morais, Sergi; Giménez-Romero, David (Elsevier, 2017)

[EN] An autoantigen piezoelectric sensor to quantify specific circulating autoantibodies in human serum is developed. The sensor consisted on a quartz crystal microbalance with dissipation monitoring (QCM-D) where TRIM21 ...
Mapping molecular binding by means of conformational dynamics measurements

Do Nascimento, Noelle M.; Juste-Dolz, Augusto Miguel; Bueno, Paulo Roberto; Monzó, Isidro S.; Tejero, R.; López-Paz, José Luis; Maquieira Catala, Angel; Morais, Sergi; Giménez-Romero, David (The Royal Society of Chemistry, 2018-01)

[EN] Protein-protein interactions are key in virtually all biological processes. The study of these interactions and the interfaces that mediate them play a key role in the understanding of biological function. In particular, ...
New structural insights into the role of TROVE2 complexes in the on-set and pathogenesis of systemic lupus eythematosus determined by a combiantion of QCM-D and DPI

Juste-Dolz, Augusto Miguel; Do Nascimento, Noelle Mariane; Monzó, Isidro S.; Grau-García, Elena; Roman-Ivorra, J. A.; López-Paz, José Luis; Escorihuela Fuentes, Jorge; Puchades, Rosa; Morais, Sergi; Giménez-Romero, David; Maquieira Catala, Angel (Springer-Verlag, 2019-07)

[EN] The mechanism of self-recognition of the autoantigen TROVE2, a common biomarker in autoimmune diseases, has been studied with a quartz crystal microbalance with dissipation monitoring (QCM-D) and dual polarization ...
The Ro/SSA Complex in Systemic Lupus Erythematosus Patients

Do Nascimento, Noelle Mariane (Universitat Politècnica de València, 2017-05-04)

In this work the involved mechanisms between Ro/SSA complex, composed also by the tripartite motif 21 (TRIM21alpha) and trove domain 2 (TROVE2) proteins, with respect to systemic lupus erythematosus (SLE) autoantibodies ...
Unveiling the RO60-RO52 complex

Rodríguez, Laura R.; de Julián-Ortiz, J.V.; Rubio de la Rúa, Fernando; Juste-Dolz, Augusto Miguel; Angel Maquieira Catala; Mohammad-Salim, Haydar A.; Benmetir, Sofiane; Pallardó-Calatayud, Federico V.; González-Cabo, Pilar; Giménez-Romero, David (EXCLI Journal, 2024-06)

[EN] The coexistence within a subcellular complex of inter -cellular proteins Ro60, responsible for preserving ncRNA quality, and Ro52, involved in intracellular proteolysis, has been a subject of ongoing debate. Employing ...