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Listar por autor "de la Torre Paredes, Cristina"

Mostrando ítems 1-20 de 20

A chemosensor bearing sulfonyl azide moieties for selective chromo-fluorogenic hydrogen sulfide recognition in aqueous media and in living cells

Santos Figueroa, Luis Enrique; De la Torre Paredes, Cristina; El Sayed Shehata Nasr, Sameh; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Costero Nieto, Ana María; Gil Grau, Salvador; Parra, Margarita (Wiley-VCH Verlag, 2014-03)

A simple chemodosimeter based on a sulfonyl azide dye (1-Az), which displayed a highly selective response toward hydrogen sulfide anion in mixed aqueous media, was synthesised and characterised. Addition of hydrogen sulfide ...
A glutathione disulfide-sensitive Janus nanomachine controlled by an enzymatic AND logic gate for smart delivery

Mayol, Beatriz; Diez-Sánchez, Paula; Sánchez, Alfredo; De La Torre, Cristina; Villalonga, Anabel; Lucena-Sánchez, Elena; Sancenón Galarza, Félix; Martinez-Ruiz, Paloma; Vilela, Diana; Martínez-Máñez, Ramón; Villalonga, Reynaldo (The Royal Society of Chemistry, 2021-11-18)

[EN] This work describes the assembly of a novel enzyme-controlled nanomachine operated through an AND Boolean logic gate for on-command delivery. The nanodevice was constructed on Au-mesoporous silica Janus nanoparticles ...
A Nanoprobe Based on Gated Mesoporous Silica Nanoparticles for The Selective and Sensitive Detection of Benzene Metabolite t,t-Muconic Acid in Urine

Domínguez-Rodríguez, Marcia; Blandez, Juan F.; Lozano-Torres, Beatriz; De La Torre-Paredes, Cristina; Licchelli, Maurizio; Mangano, Carlo; Amendola, Valeria; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (John Wiley & Sons, 2021-01-18)

[EN] Benzene is a highly toxic aromatic hydrocarbon. Inhaling benzene can cause dizziness, vertigo, headaches, aplasia, mutations and, in the most extreme cases, cancer. Trans,trans-muconic acid (t,t-MA) is one of the ...
Caspase 3 Targeted Cargo Delivery in Apoptotic Cells Using Capped Mesoporous Silica Nanoparticles

De la Torre Paredes, Cristina; Mondragón Martínez, Laura; Coll Merino, Mª Carmen; García-Fernández, Alba; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Amorós, Pedro; Pérez Payá, Enrique; Orzáez, Mar (John Wiley & Sons, 2015-10-26)

[EN] Excessive apoptotic cell death is at the origin of several pathologies, such as degenerative disorders, stroke or ischemia-reperfusion damage. In this context, strategies to improve inhibition of apoptosis and other ...
Design of a low-cost equipment for optical hyperthermia

Montes-Robles, Roberto; Hernández-Montoto, Andy; Ibáñez Civera, Francisco Javier; Masot Peris, Rafael; De La Torre-Paredes, Cristina; Martínez-Máñez, Ramón; Garcia-Breijo, Eduardo; Fraile Muñoz, Rubén (Elsevier, 2017)

[EN] A laser equipment is presented which has been specifically designed for optical hyperthermia. Such specificity in the design has allowed implementation at costs significantly lower than other options currently available ...
Drug delivery nanosystems for the localized treatment of glioblastoma multiforme

Nam, L.; Coll Merino, Mª Carmen; Erthal, L.C.S.; De La Torre-Paredes, Cristina; Serrano,D.; Martínez-Máñez, Ramón; Santos-Martinez, M.J.; Ruiz Hernández, E. (MDPI AG, 2018-05)

[EN] Glioblastoma multiforme is one of the most prevalent and malignant forms of central nervous system tumors. The treatment of glioblastoma remains a great challenge due to its location in the intracranial space and the ...
Encapsulation of folic acid in different silica porous supports: A comparative study

Pérez-Esteve, Édgar; Ruiz Rico, María; De la Torre Paredes, Cristina; Villaescusa Alonso, Luis Angel; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Amoros del Toro, Pedro Jose; Martínez-Máñez, Ramón; Barat Baviera, José Manuel (Elsevier, 2016-04-01)

Although folic acid is essential to numerous bodily functions, recent research indicates that a massive exposition to the vitamin could be a double-edged sword. In this study, the capacity of different caped mesoporous ...
Enzyme-Controlled Nanodevice for Acetylcholine-Triggered Cargo Delivery Based on Janus Au-Mesoporous Silica Nanoparticles

Llopis-Lorente, Antoni; Díez, Paula; De La Torre-Paredes, Cristina; Sanchez, Alfredo; Sancenón Galarza, Félix; Aznar, Elena; Marcos Martínez, María Dolores; Martínez-Ruíz, Paloma; Martínez-Máñez, Ramón; Villalonga, Reynaldo (John Wiley & Sons, 2017-03-28)

[EN] This work reports a new gated nanodevice for acetylcholine-triggered cargo delivery. We prepared and characterized Janus Au-mesoporous silica nanoparticles functionalized with acetylcholinesterase on the Au face and ...
epsilon-Polylysine-Capped Mesoporous Silica Nanoparticles as Carrier of the C9h Peptide to Induce Apoptosis in Cancer Cells

De La Torre-Paredes, Cristina; Domínguez-Berrocal, L.; Murguía, Jose R.; Marcos Martínez, María Dolores; Martínez-Máñez, Ramón; Bravo,J.; Sancenón Galarza, Félix (John Wiley & Sons, 2018-02)

[EN] Apoptotic signaling pathways are altered in numerous pathologies such as cancer. In this scenario, caspase-9/PP2Ac alpha interaction constitutes a key target with pharmacological interest to re-establish apoptosis in ...
Ex Vivo Tracking of Endogenous CO with a Ruthenium(II) Complex

De La Torre-Paredes, Cristina; Toscani, Anita; Marín-Hernández, Cristina; Robson, Jonathan A.; Terencio, M. Carmen; White, Andrew J.P.; Alcaraz, M. José; Wilton-Ely, James D.E.T.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (American Chemical Society, 2017-12-27)

[EN] A two-photon fluorescent probe based on a ruthenium(II) vinyl complex is capable of selectively detecting carbon monoxide in cells and ex vivo using mice with a subcutaneous air pouch as a model for inflammation. This ...
Growth, crystal structure, Hirshfeld surface analysis, DFT studies, physicochemical characterization, and cytotoxicity assays of novel organic triphosphate

Oueslati, Yathreb; Kansiz, Sevgi; Dege, Necmi; de La Torre Paredes, Cristina; Llopis-Lorente, Antoni; Martínez-Máñez, Ramón; Sta, Wajda Smirani (Springer-Verlag, 2022-03)

[EN] A novel organic-inorganic hybrid compound, named (1-phenylpiperazinium) trihydrogen triphosphate, with the formula-(C10H15N2)(2)H3P3O10 has been obtained by low speed of evaporation of a mixture of an alcoholic solution ...
Highly selective fluorescence detection of hydrogen sulfide by using an anthracene-functionalized cyclam-CuII complex

Santos Figueroa, Luis Enrique; De la Torre Paredes, Cristina; El Sayed Shehata Nasr, Sameh; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Costero Nieto, Ana María; Gil Grau, Salvador; Parra, Margarita (Wiley-VCH Verlag, 2014-01)

An anthracene-functionalised cyclam-copper(II) complex for the detection of HS- in aqueous environments has been prepared. This probe displays poor fluorescence but can selectively and sensitively detect HS- anions in water ...
Improving the Antimicrobial Power of Low-Effective Antimicrobial Molecules Through Nanotechnology

Ruiz Rico, María; Pérez-Esteve, Édgar; De La Torre-Paredes, Cristina; Jiménez Belenguer, Ana Isabel; Quiles Chuliá, Mª Desamparados; Marcos Martínez, María Dolores; Martínez-Máñez, Ramón; Barat Baviera, José Manuel (Blackwell Publishing, 2018)

[EN] The objective of this work was on the one hand to assess the antibacterial activity of amines anchored to the external surface of mesoporous silica particles against Listeria monocytogenes in comparison with the same ...
In Situ-Forming Gels Loaded with Stimuli-Responsive Gated Mesoporous Silica Nanoparticles for Local Sustained Drug Delivery

De La Torre, Cristina; Coll, Carmen; Ultimo, Amelia; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Ruiz-Hernández, Eduardo (MDPI AG, 2023-04)

[EN] A novel combination of in situ-forming hydrogels of hyaluronic acid with gated mesoporous materials was developed to design depots for local sustained release of chemotherapeutics. The depot consists of a hyaluronic-based ...
Nanoparticle-cell-nanoparticle communication by stigmergy to enhance poly(I:C) induced apoptosis in cancer cells

Ultimo, Amelia; De La Torre-Paredes, Cristina; Giménez, Cristina; Aznar, Elena; Coll, Carmen; Marcos Martínez, María Dolores; Murguía, Jose R.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (The Royal Society of Chemistry, 2020-07-07)

[EN] Nanoparticle-cell-nanoparticle communication by stigmergy was demonstrated using two capped nanodevices. The first community of nanoparticles (i.e.S(RA)(IFN)) is loaded with 9-cis-retinoic acid and capped with ...
Nanotechnology and supramolecular chemistry in controlled release and molecular recognition proceses for biomedical applications"

De la Torre Paredes, Cristina (Universitat Politècnica de València, 2018-01-08)

La presente tesis doctoral, titulada "Nanotecnología y química supramolecular en procesos de liberación controlada y reconocimiento molecular para aplicaciones biomédicas", se centra en dos temas importantes: el reconocimiento ...
Neoglycoenzyme-Gated Mesoporous Silica Nanoparticles: Toward the Design of Nanodevices for Pulsatile Programmed Sequential Delivery

Diez, Paula; Sanchez, Alfredo; De la Torre Paredes, Cristina; Gamella, Maria; Martínez-Ruíz, Paloma; Aznar, Elena; Martínez-Máñez, Ramón; Pingarron, José M.; Villalonga, Reynaldo (American Chemical Society, 2016-03-30)

We report herein the design of a stimulus-programmed pulsatile delivery system for sequential cargo release based on the use of a lactose-modified esterase as a capping agent in phenylboronic acid functionalized mesoporous ...
Polyglutamic Acid-Gated Mesoporous Silica Nanoparticles for Enzyme-Controlled Drug Delivery

Tukappa, Asha; Ultimo, Amelia; De la Torre Paredes, Cristina; Pardo Vicente, María Teresa; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (American Chemical Society, 2016-08-23)

Mesoporous silica nanoparticles (MSNs) are highly attractive as supports in the design of controlled delivery systems that can act as containers for the encapsulation of therapeutic agents, overcoming common issues such ...
Synthesis and In Vitro Evaluation of a Photosensitizer-BODIPY Derivative for Potential Photodynamic Therapy Applications

Gorbe, Mónica; Barba Bon, Andrea; De la Torre, Cristina; Gil Grau, Salvador; Costero Nieto, Ana María; Sancenón Galarza, Félix; Murguía, Jose R.; Martínez-Máñez, Ramón (Wiley-VCH Verlag, 2015-10)

A new photosensitizer (1) based on the 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) scaffold has been synthesized. 1 is water soluble and showed an intense absorption band at 490 nm (e=77600 cm-1M-1) and an emission ...
Validation of an automated system for the experimentation of photothermal therapies on cell cultures

Terrés-Haro, José Manuel; Hernández-Montoto, Andy; Pardo-Huguet, María; De La Torre, Cristina; Monreal-Trigo, Javier; Ibáñez Civera, Francisco Javier; Masot Peris, Rafael; Martínez-Máñez, Ramón; Garcia-Breijo, Eduardo (Elsevier, 2022-04-16)

[EN] Hyperthermia is a technique used in treatments against cancer, consisting in heating the cancerous tissue to 40-44 ºC to produce apoptosis. The addition of noble metal nanoparticles would suppose a great progress in ...