[EN] An aptasensor based on periodic 1D corrugated waveguides is demonstrated to be suitable for the specific and continuous detection of thrombin at nM concentrations in real time with an estimated detection limit of 33.5 pM.
Larrea-Luzuriaga, Roberto Alejandro; Gutiérrez Campo, Ana María; Hurtado Montañés, Juan; Ramirez, J. M.; Garrido, B.; Sanchis Kilders, Pablo(Optical Society of America, 2017-02-01)
In this Letter, we present the design, simulation (2D and 3D), fabrication, and experimental characterization of compact and fully etched focusing gratings for a horizontal slot waveguide based on a silicon nitride layer ...
[EN] Thrombin generation is a complex and finely regulated pathway that provokes dynamical changes of thrombin concentration in blood when a vascular injury occurs. In order to characterize the initiation phase of such ...
[EN] In this paper we introduce a field diagnostic device based on the combination of advanced bio-sensing and photonics technologies, to tackle emerging and endemic viruses causing swine epidemics, and consequently ...
Cortés-Juan, F.; Chaverri Ramos, Christian; Connolly, James Patrick; David, Christin; García de Abajo, Francisco Javier; Hurtado Montañés, Juan; Mihailetchi, V.D.; Ponce-Alcántara, Salvador; Sánchez Plaza, Guillermo(American Institute of Physics, 2013)
[EN] The influence of the relative position of Ag metallic nanoparticles (Ag MNPs) embedded in a 100 nm SiOx Antireflection Coating (ARC) for specular polished c-Si substrates is studied. It is demonstrated that this ...
[EN] An experimental study of the influence of the conformational change suffered by molecular beacon (MB) probesupon the biorecognition of nucleic acid target oligonucleotides over evanescent wave photonic sensorsis ...
[EN] A label-free sensor, based on the combination of silicon photonic bandgap (PBG) structures with immobilized molecular beacon (MB) probes, is experimentally developed. Complementary target oligonucleotides are specifically ...
We experimentally demonstrate a low-loss multilayered metamaterial exhibiting a double-negative refractive index in the visible spectral range. To this end, we exploit a second-order magnetic resonance of the so-called ...
[EN] Typically, materials with large optical losses such as metals are used as microheaters for silicon based thermo-optic phase shifters. Consequently, the heater must be placed far from the waveguide, which could come ...