Marín-Payá, Juan Carlos; Díaz-Benito, Blanca; Amaro Martins, Luis; Clara Trujillo, Sandra; Cordón, Lourdes; Lanceros-Méndez, Senentxu; Gallego-Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís(MDPI AG, 2021-12)
[EN] The development of three-dimensional environments to mimic the in vivo cellular response is a problem in the building of disease models. This study aimed to synthesize and validate three-dimensional support for culturing ...
Marin Paya, Juan Carlos; Díaz Benito, Blanca; Amaro Martins, Luis; Clara Trujillo, Sandra; Cordón, Lourdes; Lanceros-Mendez, Senentxu; Gallego Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís(Universitat Politècnica de València, 2021-12-14)
The development of three-dimensional environments to mimic the in vivo cellular response is a problem in the building of disease models. This study aimed to synthesize and validate three-dimensional support for culturing ...
Clara-Trujillo, Sandra; Marin-Paya, Juan Carlos; Cordón, Lourdes; Sempere, Amparo; Gallego-Ferrer, Gloria; Gómez Ribelles, José Luís(Elsevier, 2019-05-01)
[EN] Stem cells reside in niches, specialized microenvironments that sustain and regulate their fate. Extracellular matrix (ECM), paracrine factors or other cells are key niche regulating elements. As the conventional 2D ...
Clara Trujillo, Sandra(Universitat Politècnica de València, 2022-09-06)
[ES] La ingeniería tisular ha evolucionado hacia el modelado de la fisiología humana in vitro. El microambiente de la médula ósea (BM) es también hogar de procesos malignos. El mieloma múltiple (MM) es una neoplasia ...
Panova, Ekaterina(Universitat Politècnica de València, 2023-11-03)
[ES] En la actualidad, la fibrosis hepática es una de las patologías que más prevalecen en la población y
de la que no existen medicamentos efectivos para revertirla. Por ello, surge la necesidad de
desarrollar fármacos ...
Vaca-González, Juan Jairo; Clara-Trujillo, Sandra; Guillot-Ferriols, María Teresa; Ródenas Rochina, Joaquín; Sanchis Sánchez, María Jesús; Gómez Ribelles, José Luís; Garzón-Alvarado, Diego Alexander; Gallego-Ferrer, Gloria(Elsevier, 2020-08)
[EN] Electrical stimulation (ES) has provided enhanced chondrogenesis of mesenchymal stem cells (MSCs) cultured in micro-mass without the addition of exogenous growth factors. In this study, we demonstrate for the first ...
Solano-Martínez, Concha; Clara Trujillo, Sandra; Guillot Ferriols, María Teresa; Gómez Estrada, Luis; Gómez Ribelles, José Luís(Editorial Universitat Politècnica de València, 2019-09-30)
[EN] This communication summarizes the results of the Erasmus+ project
"CRİTİCAL THİNKİNG AS A STEP FORWARD İN VET EDUCATİON: VET
students immersed in high technology teams" in which european technologybased companies, ...
Esteban Arias, Angela(Universitat Politècnica de València, 2019-09-03)
[ES] Actualmente la producción de modelos de médula ósea tridimensionales supone un reto en el
campo de la ingeniería tisular ya que permitiría el avance hacia tratamientos personalizados en
pacientes de mieloma múltiple ...
Clara-Trujillo, Sandra; Gallego-Ferrer, Gloria; Gómez Ribelles, José Luís(MDPI AG, 2020-08)
[EN] In hematological malignancies, leukemias or myelomas, malignant cells present bone marrow (BM) homing, in which the niche contributes to tumor development and drug resistance. BM architecture, cellular and molecular ...
Clara Trujillo, Sandra(Universitat Politècnica de València, 2016-09-02)
[ES] El objetivo de este trabajo ha sido la preparación, caracterización y estudio de la
viabilidad celular de matrices extracelulares sintéticas formadas por micropartículas
poliméricas que responden a campos magnéticos ...
[EN] Multiple myeloma (MM) is a hematological malignancy in which the patient's drug resistance is one of the main clinical problems. As 2D cultures do not recapitulate the cellular microenvironment, which has a key role ...
Plá Salom, Júlia(Universitat Politècnica de València, 2021-09-09)
[ES] El mieloma múltiple es una neoplasia de las células plasmáticas que se desarrolla en la médula ósea. En la progresión de esta enfermedad y en el desarrollo de resistencias a fármacos, la interacción entre las células ...
Marin-Paya, Juan Carlos; Clara-Trujillo, Sandra; Cordón, Lourdes; Gallego-Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís(MDPI AG, 2022-11)
[EN] Multiple myeloma is a hematologic neoplasm caused by an uncontrolled clonal proliferation of neoplastic plasma cells (nPCs) in the bone marrow. The development and survival of this disease is tightly related to the ...
Marín Pallá, Juan Carlos; Clara Trujillo, Sandra; Cordón, Lourdes; Gallego Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís(MDPIUniversitat Politècnica de València, 2022-11-21)
Multiple myeloma is a hematologic neoplasm caused by an uncontrolled clonal proliferation
of neoplastic plasma cells (nPCs) in the bone marrow. The development and survival of this disease is
tightly related to the bone ...