[EN] Multiscale cardiac modelling has been increasingly
used since it provides a promising framework to improve
our understanding of atrial fibrillation physiopathology.
In this study, we present a highly detailed ...
Godoy, Eduardo J.; Lozano, Miguel; García-Fernández, Ignacio; Ferrer-Albero, Ana; MacLeod, Rob; Saiz, Javier; Sebastián, Rafael(Frontiers Media SA, 2018-05-18)
[EN] Introduction: Focal atrial tachycardia is commonly treated by radio frequency ablation with an acceptable long-term success. Although the location of ectopic foci tends to appear in specific hot-spots, they can be ...
Carbonell Pascual, Beatriz; Godoy, Eduardo Jorge; Ferrer Albero, Ana; Romero Pérez, Lucia; Ferrero De Loma-Osorio, José María(Elsevier, 2016-06-21)
When simulating the macroscopic current flowing through cardiac ion channels, two mathematical
formalisms can be adopted: the Hodgkin–Huxley model (HHM) formulation, which describes openings
and closings of channel ...
Ferrer Albero, Ana; Sebastián Aguilar, Rafael; Sánchez Quintana, Damián; Rodriguez, José F.; Godoy, Eduardo Jorge; Martinez, Laura; Saiz Rodríguez, Francisco Javier(Public Library of Science, 2015-11-02)
Atrial arrhythmias, and specifically atrial fibrillation (AF), induce rapid and irregular activation patterns that appear on the torso surface as abnormal P-waves in electrocardiograms and body surface potential maps (BSPM). ...
Martínez-Mateu, Laura; Romero Pérez, Lucia; Ferrer Albero, Ana; Sebastián Aguilar, Rafael; Rodriguez Matas, José Félix; Jalife, José; Berenfeld, Omer; Saiz Rodríguez, Francisco Javier(Public Library of Science, 2018-03)
[EN] Anatomically based procedures to ablate atrial fibrillation (AF) are often successful in terminating paroxysmal AF. However, the ability to terminate persistent AF remains disappointing. New mechanistic approaches use ...
Sebastián Aguilar, Rafael; Ferrer Albero, Ana; Saiz Rodríguez, Francisco Javier(Universitat Politècnica de València, 2015-09-28)
Computational 3D models of human atria and torso with encoded anatomical and functional heterogeneity. The finite element model of the atria is a multi-layer mesh with a homogeneous wall thickness between 600 and 900 μm ...
Ferrer Albero, Ana(Universitat Politècnica de València, 2013-03-21)
[ES] El desarrollo de modelos computacionales en el campo de la electrofisiología cardiaca ha permitido
analizar in-silico el comportamiento auricular tanto a nivel celular y tisular como de órgano completo.
Todos estos ...
Ferrer Albero, Ana; Godoy, Eduardo Jorge; Lozano, Miguel; Martínez Mateu, Laura; Alonso Atienza, Felipe; Saiz Rodríguez, Francisco Javier; Sebastián Aguilar, Rafael(Public Library of Science, 2017-07-13)
Non-invasive localization of continuous atrial ectopic beats remains a cornerstone for the treatment of atrial arrhythmias. The lack of accurate tools to guide electrophysiologists leads to an increase in the recurrence ...
Ferrer Albero, Ana(Universitat Politècnica de València, 2017-10-02)
A better understanding of the electrical activity of the heart under physiological and pathological conditions has always been key for clinicians and researchers. Over the last years, the information in the P-wave signals ...
[EN] Background¿ Ventricular fibrillation (VF) has been proposed to be maintained by localized high-frequency sources. We tested whether spectral-phase analysis of the precordial ECG enabled identification of periodic ...