de Luis-Fernández, Beatriz; García-Fernández, Alba; Llopis-Lorente, Antoni; Villalonga, Reynaldo; Sancenón Galarza, Félix; Martínez-Máñez, Ramón(The Royal Society of Chemistry, 2020-09-07)
[EN] A biocomputing strategy implemented in hybrid nanocarriers for controlled cargo delivery is described. The nanodevice consists of enzyme-functionalized Janus Au-mesoporous silica nanoparticles, which behave as an ...
Santos Figueroa, Luis Enrique; Llopis Lorente, Antoni; Royo Calvo, Santiago; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Costero, Ana M.; Gil Grau, Salvador; Parra Álvarez, Margarita(Wiley-VCH Verlag, 2015-05)
[EN] Anew chalcone-based probe for the chromofluorogenic sens-ing of trivalent (Al3 +,Fe3+,Cr3+,Ga3+,In3+and As3 +)overmono-and divalent cationsand anionsisreported. In the presence of trivalent metal cations,the probe was ...
de Luis-Fernández, Beatriz; Morella-Aucejo, Ángela; Llopis-Lorente, Antoni; Godoy-Reyes, Tania Mariel; Villalonga, Reynaldo; Aznar, Elena; Sancenón Galarza, Félix; Martínez-Máñez, Ramón(The Royal Society of Chemistry, 2021-01-28)
[EN] In nature, coordinated communication between different entities enables a group to accomplish sophisticated functionalities that go beyond those carried out by individual agents. The possibility of programming and ...
Casula, A.; Llopis-Lorente, Antoni; Garau, A.; Isaia, F.; Kubicki, M.; Lippolis, V.; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Owczarzak, A.; Santi, C.; Andrea Scorciapino, M.; Caltagirone, C.(The Royal Society of Chemistry, 2017)
[EN] The first example of a chemosensor (L) containing a selenourea moiety is described here. L is able to colorimetrically sense the presence of CN- and S2- in H2O: MeCN (75 : 25, v/v). Moreover, when L is loaded into ...
Hernández-Montoto, Andy; Gorbe, Mónica; Llopis-Lorente, Antoni; Terrés-Haro, José Manuel; Montes-Robles, Roberto; Cao Milán, Roberto; Díaz de Greñu-Puertas, Borja; Alfonso-Navarro, María; Orzaez, Mar; Marcos Martínez, María Dolores; Martínez-Máñez, Ramón; Sancenón Galarza, Félix(The Royal Society of Chemistry, 2019-08-07)
[EN] Gold nanostars coated with a mesoporous silica shell and functionalized with poly(ethylene glycol) containing photolabile 2-nitrobenzyl moieties are able to release doxorubicin after NIR light irradiation at low power ...
[EN] Here, a new bio-inspired nanoarchitectonics approach for the design of optical probes is presented. It is based on nanodevices that combine 1) an enzymatic receptor subunit, 2) a signaling subunit (consisting of a ...
Godoy-Reyes, Tania Mariel; Llopis-Lorente, Antoni; García-Fernández, Alba; Gaviña, Pablo; Costero, Ana M.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix(The Royal Society of Chemistry, 2019)
[EN] Mesoporous silica nanoparticles capped with acetylcholinesterase, through boronic ester linkages, selectively release an entrapped cargo in the presence of acetylcholine.
[EN] The construction of communication models at the micro¿/nanoscale involving abiotic nanodevices and living organisms has the potential to open a wide range of applications in biomedical and communication technologies. ...
Llopis-Lorente, Antoni; de Luis-Fernández, Beatriz; García-Fernández, Alba; Diez, Paula; Sánchez, Alfredo; Marcos Martínez, María Dolores; Villalonga, Reynaldo; Martínez-Máñez, Ramón; Sancenón Galarza, Félix(The Royal Society of Chemistry, 2017)
[EN] We report a delivery system based on Au-mesoporous silica (MS) nanoparticles functionalized with acetylcholinesterase on the Au face as a control unit and with disulfide-containing oligo(ethylene glycol) chains on the ...
Altay, Yigit; Llopis-Lorente, Antoni; Abdelmohsen, Loai K. E. A.; van Hest, Jan C.M.(John Wiley & Sons, 2023-01)
[EN] Harnessing interactions of functional nano-compartments to generate larger particle assemblies allows studying diverse biological behaviors based on their population states and can lead to the development of smart ...
Song, Shidong; Llopis-Lorente, Antoni; Mason, Alexander F.; Abdelmohsen, Loai K.E.; van Hest, Jan C. M.(American Chemical Society, 2022-08-03)
[EN] Active materials can transduce external energy into kinetic energy at the nano and micron length scales. This unique feature has sparked much research, which ranges from achieving fundamental understanding of their ...
de Luis Fernández, Beatriz(Universitat Politècnica de València, 2021-09-02)
[ES] La presente tesis doctoral se centra en el diseño, síntesis y caracterización de varios nanodispositivos híbridos orgánico-inorgánicos, utilizando como soporte nanopartículas de sílice mesoporosa equipadas con enzimas ...
de Luis-Fernández, Beatriz; Llopis-Lorente, Antoni; Sancenón Galarza, Félix; Martínez-Máñez, Ramón(The Royal Society of Chemistry, 2021-08-21)
[EN] Chemical communication, based on the exchange of molecules as messengers, allows different entities to share information, cooperate and orchestrate collective behaviors. In recent years, the development of strategies ...
Llopis-Lorente, Antoni; Díez, Paula; De La Torre-Paredes, Cristina; Sanchez, Alfredo; Sancenón Galarza, Félix; Aznar, Elena; Marcos Martínez, María Dolores; Martínez-Ruíz, Paloma; Martínez-Máñez, Ramón; Villalonga, Reynaldo(John Wiley & Sons, 2017-03-28)
[EN] This work reports a new gated nanodevice for acetylcholine-triggered cargo delivery. We prepared and characterized Janus Au-mesoporous silica nanoparticles functionalized with acetylcholinesterase on the Au face and ...
Llopis Lorente, Antoni(Universitat Politècnica de València, 2019-03-04)
[ES] La presente tesis doctoral titulada "Nanodispositivos mesoporosos híbridos funcionalizados con enzimas para detección, liberación controlada y comunicación molecular" se centra en el diseño, preparación, caracterización ...
[EN] The introduction of stimuli-responsive cargo release capabilities on self-propelled micro- and nano- motors holds enormous potential in a number of applications in the biomedical field. Herein, we report the preparation ...
[EN] Here we describe the construction of an integrated and pH-sensitive nanomachine with layer-by-layer supramolecular design and enzymatic control for on-command delivery. The nanodevice comprises a first layer of ...
Oueslati, Yathreb; Kansiz, Sevgi; Dege, Necmi; de La Torre Paredes, Cristina; Llopis-Lorente, Antoni; Martínez-Máñez, Ramón; Sta, Wajda Smirani(Springer-Verlag, 2022-03)
[EN] A novel organic-inorganic hybrid compound, named (1-phenylpiperazinium) trihydrogen triphosphate, with the formula-(C10H15N2)(2)H3P3O10 has been obtained by low speed of evaporation of a mixture of an alcoholic solution ...
[EN] Introduction: Breast cancer has the highest mortality rate among cancers in women. Patients suffering from certain breast cancers, such as triple-negative breast cancer (TNBC), lack effective treatments. This represents ...
[EN] Here, we present the design of smart nano-devices capable of reading molecular information from the environment and acting accordingly by processing Boolean logic tasks. As proof of concept, we prepared Au-mesoporous ...