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Listar por autor "Llopis Lorente, Antoni"

Mostrando ítems 1-20 de 35

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A 1-to-2 demultiplexer hybrid nanocarrier for cargo delivery and activation

de Luis-Fernández, Beatriz; García-Fernández, Alba; Llopis-Lorente, Antoni; Villalonga, Reynaldo; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (The Royal Society of Chemistry, 2020-09-07)

[EN] A biocomputing strategy implemented in hybrid nanocarriers for controlled cargo delivery is described. The nanodevice consists of enzyme-functionalized Janus Au-mesoporous silica nanoparticles, which behave as an ...
A chalcone-based highly selective and sensitive chromofluorogenic probe for trivalent metal cations

Santos Figueroa, Luis Enrique; Llopis Lorente, Antoni; Royo Calvo, Santiago; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Costero, Ana M.; Gil Grau, Salvador; Parra Álvarez, Margarita (Wiley-VCH Verlag, 2015-05)

[EN] Anew chalcone-based probe for the chromofluorogenic sens-ing of trivalent (Al3 +,Fe3+,Cr3+,Ga3+,In3+and As3 +)overmono-and divalent cationsand anionsisreported. In the presence of trivalent metal cations,the probe was ...
A chemical circular communication network at the nanoscale

de Luis-Fernández, Beatriz; Morella-Aucejo, Ángela; Llopis-Lorente, Antoni; Godoy-Reyes, Tania Mariel; Villalonga, Reynaldo; Aznar, Elena; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (The Royal Society of Chemistry, 2021-01-28)

[EN] In nature, coordinated communication between different entities enables a group to accomplish sophisticated functionalities that go beyond those carried out by individual agents. The possibility of programming and ...
A l-glutamate-responsive delivery system based on enzyme-controlled self-immolative arylboronate-gated nanoparticles

Godoy-Reyes, Tania Mariel; Llopis-Lorente, Antoni; García-Fernández, Alba; Gaviña, Pablo; Costero, Ana M.; Villalonga, Reynaldo; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (Royal Society of Chemistry, 2019-04-07)

[EN] We report herein a l-glutamate (l-Glu)-responsive delivery system. It consists of Janus Au-mesoporous silica (MS) nanoparticles functionalized with l-glutamate oxidase on the Au face and with self-immolative arylboronate ...
A new class of silica-supported chromo-fluorogenic chemosensors for anion recognition based on a selenourea scaffold

Casula, A.; Llopis-Lorente, Antoni; Garau, A.; Isaia, F.; Kubicki, M.; Lippolis, V.; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Owczarzak, A.; Santi, C.; Andrea Scorciapino, M.; Caltagirone, C. (The Royal Society of Chemistry, 2017)

[EN] The first example of a chemosensor (L) containing a selenourea moiety is described here. L is able to colorimetrically sense the presence of CN- and S2- in H2O: MeCN (75 : 25, v/v). Moreover, when L is loaded into ...
A NIR light-triggered drug delivery system using core-shell gold nanostars-mesoporous silica nanoparticles based on multiphoton absorption photo-dissociation of 2-nitrobenzyl PEG

Hernández-Montoto, Andy; Gorbe, Mónica; Llopis-Lorente, Antoni; Terrés-Haro, José Manuel; Montes-Robles, Roberto; Cao Milán, Roberto; Díaz de Greñu-Puertas, Borja; Alfonso-Navarro, María; Orzaez, Mar; Marcos Martínez, María Dolores; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (The Royal Society of Chemistry, 2019-08-07)

[EN] Gold nanostars coated with a mesoporous silica shell and functionalized with poly(ethylene glycol) containing photolabile 2-nitrobenzyl moieties are able to release doxorubicin after NIR light irradiation at low power ...
A Versatile New Paradigm for the Design of Optical Nanosensors Based on Enzyme-Mediated Detachment of Labeled Reporters: The Example of Urea Detection

Llopis-Lorente, Antoni; VILLALONGA, REYNALDO; Marcos Martínez, María Dolores; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (John Wiley & Sons, 2019-03-07)

[EN] Here, a new bio-inspired nanoarchitectonics approach for the design of optical probes is presented. It is based on nanodevices that combine 1) an enzymatic receptor subunit, 2) a signaling subunit (consisting of a ...
Acetylcholine-responsive cargo release using acetylcholinesterase-capped nanomaterials

Godoy-Reyes, Tania Mariel; Llopis-Lorente, Antoni; García-Fernández, Alba; Gaviña, Pablo; Costero, Ana M.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (The Royal Society of Chemistry, 2019)

[EN] Mesoporous silica nanoparticles capped with acetylcholinesterase, through boronic ester linkages, selectively release an entrapped cargo in the presence of acetylcholine.
Achieving Control in Micro-/Nanomotor Mobility

Fusi, Alexander D.; Li, Yudong; Llopis-Lorente, Antoni; Patiño, Tania; van Hest, Jan C.M.; Abdelmohsen, Loai K.E. (John Wiley & Sons, 2023)
An Interactive Model of Communication between Abiotic Nanodevices and Microorganisms

de Luis-Fernández, Beatriz; Llopis-Lorente, Antoni; Rincón, Paola; Gadea Vacas, José; Sancenón Galarza, Félix; Aznar, Elena; Villalonga, Reynaldo; Murguía, Jose R.; Martínez-Máñez, Ramón (John Wiley & Sons, 2019-10-14)

[EN] The construction of communication models at the micro¿/nanoscale involving abiotic nanodevices and living organisms has the potential to open a wide range of applications in biomedical and communication technologies. ...
Au-Mesoporous silica nanoparticles gated with disulfide-linked oligo(ethylene glycol) chains for tunable cargo delivery mediated by an integrated enzymatic control unit

Llopis-Lorente, Antoni; de Luis-Fernández, Beatriz; García-Fernández, Alba; Diez, Paula; Sánchez, Alfredo; Marcos Martínez, María Dolores; Villalonga, Reynaldo; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (The Royal Society of Chemistry, 2017)

[EN] We report a delivery system based on Au-mesoporous silica (MS) nanoparticles functionalized with acetylcholinesterase on the Au face as a control unit and with disulfide-containing oligo(ethylene glycol) chains on the ...
Chemical Cascading Between Polymersomal Nanoreactor Populations

Altay, Yigit; Llopis-Lorente, Antoni; Abdelmohsen, Loai K. E. A.; van Hest, Jan C.M. (John Wiley & Sons, 2023-01)

[EN] Harnessing interactions of functional nano-compartments to generate larger particle assemblies allows studying diverse biological behaviors based on their population states and can lead to the development of smart ...
Confined Motion: Motility of Active Microparticles in Cell-Sized Lipid Vesicles

Song, Shidong; Llopis-Lorente, Antoni; Mason, Alexander F.; Abdelmohsen, Loai K.E.; van Hest, Jan C. M. (American Chemical Society, 2022-08-03)

[EN] Active materials can transduce external energy into kinetic energy at the nano and micron length scales. This unique feature has sparked much research, which ranges from achieving fundamental understanding of their ...
Development of enzyme-functionalized hybrid mesoporous nanodevices for advanced chemical communication

de Luis Fernández, Beatriz (Universitat Politècnica de València, 2021-09-02)

[ES] La presente tesis doctoral se centra en el diseño, síntesis y caracterización de varios nanodispositivos híbridos orgánico-inorgánicos, utilizando como soporte nanopartículas de sílice mesoporosa equipadas con enzimas ...
Development of Lipid Nanoparticles for Enzymatic Therapies

Blázquez Ruiz, Marta (Universitat Politècnica de València, 2024-05-14)

[ES] El cáncer es una enfermedad compleja, con un gran impacto a nivel mundial y una alta tasa de mortalidad debido a las limitaciones existentes de los tratamientos disponibles. La quimioterapia es uno de los tratamientos ...
Engineering chemical communication between micro/nanosystems

de Luis-Fernández, Beatriz; Llopis-Lorente, Antoni; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (The Royal Society of Chemistry, 2021-08-21)

[EN] Chemical communication, based on the exchange of molecules as messengers, allows different entities to share information, cooperate and orchestrate collective behaviors. In recent years, the development of strategies ...
Enzyme-Controlled Nanodevice for Acetylcholine-Triggered Cargo Delivery Based on Janus Au-Mesoporous Silica Nanoparticles

Llopis-Lorente, Antoni; Díez, Paula; De La Torre-Paredes, Cristina; Sanchez, Alfredo; Sancenón Galarza, Félix; Aznar, Elena; Marcos Martínez, María Dolores; Martínez-Ruíz, Paloma; Martínez-Máñez, Ramón; Villalonga, Reynaldo (John Wiley & Sons, 2017-03-28)

[EN] This work reports a new gated nanodevice for acetylcholine-triggered cargo delivery. We prepared and characterized Janus Au-mesoporous silica nanoparticles functionalized with acetylcholinesterase on the Au face and ...
Enzyme-functionalized hybrid mesoporous nanodevices for sensing, controlled release and molecular communication

Llopis Lorente, Antoni (Universitat Politècnica de València, 2019-03-04)

[ES] La presente tesis doctoral titulada "Nanodispositivos mesoporosos híbridos funcionalizados con enzimas para detección, liberación controlada y comunicación molecular" se centra en el diseño, preparación, caracterización ...
Enzyme-Powered Gated Mesoporous Silica Nanomotors for On-Command Intracellular Payload Delivery

Llopis-Lorente, Antoni; García-Fernández, Alba; Murillo-Cremaes, N.; Hortelao, A.C.; Patiño, T.; Villalonga, R.; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Sanchez, S. (American Chemical Society, 2019-10)

[EN] The introduction of stimuli-responsive cargo release capabilities on self-propelled micro- and nano- motors holds enormous potential in a number of applications in the biomedical field. Herein, we report the preparation ...
Facile synthesis of rapamycin-loaded PEG-b-PLA nanoparticles and their application in immunotherapy

Li, Yudong; Scheerstra, Jari F.; Liu, Yuechi; Wauters, Annelies C.; Wang, Jianhong; Wu, Hanglong; Patiño, Tania; Llopis-Lorente, Antoni; van Hest, J.C.M.; Abdelmohsen, L.K.E. (John Wiley & Sons, 2024-05-15)

[EN] Poly(ethylene glycol)-block-poly(lactide) (PEG-b-PLA) micro- and nanoparticles (NPs) have been intensively investigated for applications in biomedicine, due to their inherent biocompatibility and biodegradability, ...