Buscar en RiuNet

Listar

Todo RiuNet

Mi cuenta

Acceder

Ayuda RiuNet

Admin. UPV

Listar por autor "Molins Molina, Óscar"

Mostrando ítems 1-6 de 6

Estudio fotofísico y fotoquímico del 4-Trifluorometil-1-Naftol

Molins Molina, Óscar (Universitat Politècnica de València, 2015-07-17)
Identification of a common recognition center for a photoactive non-steroidal antiinflammatory drug in serum albumins of different species

Molins-Molina, Oscar; Lence, Emilio; Limones-Herrero, Daniel; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo (Royal Society of Chemistry, 2019-01-07)

[EN] The non-steroidal anti-inflammatory drug (S)-carprofen (CPF) has been used as a photoactive probe to investigate the possible existence of a common recognition center in serum albumins (SAs) of different species. The ...
Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies

Molins-Molina, Oscar; Pérez Ruiz, Raúl; Lence, Emilio; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo (Frontiers Media SA, 2019-09-20)

[EN] Triflusal is a platelet antiaggregant employed for the treatment and prevention of thromboembolic diseases. After administration, it is biotransformed into its active metabolite, the 2-hydroxy-4-trifluoromethylbenzoic ...
Photogeneration of Quinone Methides as Latent Electrophiles for Lysine Targeting

Pérez Ruiz, Raul; Molins-Molina, Oscar; Lence, Emilio; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo (American Chemical Society, 2018-11-02)

[EN] Latent electrophiles are nowadays very attractive chemical entities for drug discovery, as they are unreactive unless activated upon binding with the specific target. In this work, the utility of 4-trifluoromethyl ...
Singlet oxygen production and in vitro phototoxicity studies on fenofibrate, mycophenolate mofetil, trifusal, and their active metabolites

Molins-Molina, Oscar; Bresolí-Obach, Roger; García-Laínez, G.; Andreu Ros, María Inmaculada; Nonell, Santiago; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo (John Wiley & Sons, 2017-09)

[EN] Singlet oxygen photosensitization (studied by time-resolved near-infrared emission spectroscopy) and in vitro phototoxicity (by means of the 3T3 neutral red uptake assay) have been investigated for the prodrugs ...
Unión fotoquímica irreversible de ligandos a albúminas séricas

Molins Molina, Óscar (Universitat Politècnica de València, 2020-03-27)

[ES] En esta tesis se ha desarrollado una estrategia multidisciplinar que incluye la irradiación de complejos ligando/proteína junto con estudios de fluorescencia y/o espectroscopía de absorción transitoria, cromatografía ...