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Listar por autor "Pla Blasco, Luis"

Mostrando ítems 1-11 de 11

A fluorogenic capped mesoporous aptasensor for gluten detection

Pla, Luis; Martínez-Bisbal, M.Carmen; Aznar, Elena; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Santiago Felipe, Sara (Elsevier, 2021-02-22)

[EN] Celiac disease is a complex and autoimmune disorder caused by the ingestion of gluten affecting almost 1% of global population. Nowadays an effective treatment does not exist, and the only way to manage the disease ...
A gated material as immunosensor for in-tissue detection of IDH1-R132H mutation in gliomas

Pla, Luis; Sancenón Galarza, Félix; Martínez-Bisbal, M.Carmen; Prat-Acín, Ricardo; Galeano-Senabre, Inmaculada; Botello-Marabotto, Marina Dolores; Palanca-Suela, Sarai; Aznar, Elena; Santiago Felipe, Sara; Martínez-Máñez, Ramón (Elsevier, 2021-10-15)

[EN] A nanodevice consisted on nanoporous anodic alumina (NAA) supports functionalized with specific and selective antibody-based gatekeepers for the detection of IDH1-R132H mutant enzyme is here reported. Molecular profile ...
A new 8-oxo-7,8-2 ' deoxyguanosine nanoporous anodic alumina aptasensor for colorectal cancer diagnosis in blood and urine

Pla, Luis; Sancenón Galarza, Félix; Martínez-Bisbal, M.Carmen; Bañuls, Celia; Estañ, Nuria; Botello-Marabotto, Marina Dolores; Aznar, Elena; Sáez, Guillermo; Santiago-Felipe, Sara; Martínez-Máñez, Ramón (The Royal Society of Chemistry, 2021-05-14)

[EN] Many important human diseases, and especially cancer, have been related to the overproduction of 8-oxo-7,8-dihydro-2 '-deoxyguanosine (8-oxo-dG). This molecule is a product of oxidative stress processes over nucleophilic ...
Aptamer-Capped Nanoporous Anodic Alumina for SARS-CoV-2 Spike Protein Detection

Caballos-Gómez, María Isabel; Aranda, María Nieves; López-Palacios, Alba; Pla, Luis; Santiago Felipe, Sara; Hernández-Montoto, Andy; Tormo-Mas, María Ángeles; Pemán, Javier; Gómez-Ruiz, María Dolores; Calbuig, Eva; Sánchez-Sendra, Beatriz; Francés-Gómez, Clara; Geller, Ron; Aznar, Elena; Martínez-Máñez, Ramón (Wiley-VCH Verlag GmbH & Co. KGaA, 2023-06)

[EN] The COVID-19 pandemic, which began in 2019, has highlighted the importance of testing and tracking infected individuals as a means of mitigating the spread of the virus. In this context, the development of sensitive ...
Aptamer-Capped nanoporous anodic alumina for Staphylococcus aureus detection

Pla, Luis; Santiago Felipe, Sara; Tormo-Mas, María Ángeles; Pemán, Javier; Sancenón Galarza, Félix; Aznar, Elena; Martínez-Máñez, Ramón (Elsevier, 2020-10-01)

[EN] The development of new detection systems for an accurate and rapid identification of pathogens has become an essential challenge in the biomedical field. Herein a highly selective platform based on aptamer-gated nano ...
Chromogenic and Fluorogenic Probes for the Detection of Illicit Drugs

Garrido-García, Eva María; Pla, Luis; Lozano-Torres, Beatriz; El Sayed Shehata Nasr, Sameh; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (John Wiley & Sons, 2018-05)

[EN] The consumption of illicit drugs has increased exponentially in recent years and has become a problem that worries both governments and international institutions. The rapid emergence of new compounds, their easy ...
New nanostructured supports with signal amplification features for the detection of molecules and biomolecules of interest

Pla Blasco, Luis (Universitat Politècnica de València, 2021-05-17)

[ES] La presente tesis doctoral titulada "New nanostructured suports with signal amplification features for the detection of molecules and biomolecules of interest" se centra en el diseño y preparación de nuevos materiales ...
Oligonucleotide-capped nanoporous anodic alumina biosensor as diagnostic tool for rapid and accurate detection of Candida auris in clinical samples

Pla, Luis; Santiago-Felipe, Sara; Tormo-Mas, María Ángeles; Ruiz-Gaitán, Alba; Peman, Javier; Valentín, Eulogio; Sancenón Galarza, Félix; Aznar, Elena; Martínez-Máñez, Ramón (Nature Publishing Group, 2021-01-01)

[EN] Candida auris has arisen as an important multidrug-resistant fungus because of several nosocomial outbreaks and elevated rates of mortality. Accurate and rapid diagnosis of C. auris is highly desired; nevertheless, ...
Overview of the Evolution of Silica-Based Chromo-Fluorogenic Nanosensors

Pla, Luis; Lozano-Torres, Beatriz; Martínez-Máñez, Ramón; Sancenón Galarza, Félix; Ros-Lis, José Vicente (MDPI AG, 2019-11-23)

[EN] This review includes examples of silica-based, chromo-fluorogenic nanosensors with the aim of illustrating the evolution of the discipline in recent decades through relevant research developed in our group. Examples ...
The Effectiveness of Glutathione Redox Status as a Possible Tumor Marker in Colorectal Cancer

Acevedo-León, Delia; Monzó-Beltrán, Lidia; Gómez-Abril, Segundo Ángel; Estañ-Capel, Nuria; Camarasa-Lillo, Natalia; Pérez-Ebri, Marisa Luisa; Escandón-Álvarez, Jorge; Alonso-Iglesias, Eulalia; Santaolaria-Ayora, María Luisa; Carbonell-Moncho, Araceli; Ventura-Gayete, Josep; Pla, Luis; Martínez-Bisbal, M.Carmen; Martínez-Máñez, Ramón; Bagán-Debón, Leticia; Viña-Almunia, Aurora; Martínez-Santamaría, M. Amparo; Ruiz-Luque, María; Alonso-Fernández, Jorge; Bañuls, Celia; Sáez. Guillermo (MDPI AG, 2021-06)

[EN] The role of oxidative stress (OS) in cancer is a matter of great interest due to the implication of reactive oxygen species (ROS) and their oxidation products in the initiation of tumorigenesis, its progression, and ...
Triplex hybridization-based nanosystem for the rapid screening of pneumocystis pneumonia in clinical samples

Pla, Luis; Aviñó, Anna; Eritja, Ramón; Ruiz-Gaitán, Alba; Pemán, Javier; Friaza, Vicente; Calderón, Enrique J.; Aznar, Elena; Martínez-Máñez, Ramón; Santiago Felipe, Sara (MDPI, 2020-12)

[EN] Pneumocystis pneumonia (PcP) is a disease produced by the opportunistic infection of the fungus Pneumocystis jirovecii. As delayed or unsuitable treatments increase the risk of mortality, the development of rapid and ...