[EN] Celiac disease is a complex and autoimmune disorder caused by the ingestion of gluten affecting almost 1% of global population. Nowadays an effective treatment does not exist, and the only way to manage the disease ...
[EN] A nanodevice consisted on nanoporous anodic alumina (NAA) supports functionalized with specific and selective antibody-based gatekeepers for the detection of IDH1-R132H mutant enzyme is here reported. Molecular profile ...
Pla, Luis; Sancenón Galarza, Félix; Martínez-Bisbal, M.Carmen; Bañuls, Celia; Estañ, Nuria; Botello-Marabotto, Marina Dolores; Aznar, Elena; Sáez, Guillermo; Santiago-Felipe, Sara; Martínez-Máñez, Ramón(The Royal Society of Chemistry, 2021-05-14)
[EN] Many important human diseases, and especially cancer, have been related to the overproduction of 8-oxo-7,8-dihydro-2 '-deoxyguanosine (8-oxo-dG). This molecule is a product of oxidative stress processes over nucleophilic ...
Object: This study demonstrates that 3T SV-MRS data can be used with the currently available automatic brain tumour diagnostic classifiers which were trained on databases of 1.5T spectra. This will allow the existing large ...
Ibáñez Hergueta, Alejandro(Universitat Politècnica de València, 2019-10-15)
[ES] El cáncer de próstata (CaP) es el segundo cáncer más común entre la población masculina, con aproximadamente 900.000 nuevos casos cada año en todo el mundo, según la AECC. Su detección a tiempo resulta muy importante. ...
Monreal Trigo, Javier(Universitat Politècnica de València, 2019-10-28)
[ES] Los métodos actuales de detección temprana de cáncer de vejiga presentan baja sensibilidad para la
detección de tumores de bajo grado, son invasivos, de coste elevado y operador dependientes. En este
proyecto se ...
[ES] Introducción. Algunos estudios anteriores en pacientes con esquizofrenia han sugerido alteraciones morfométricas y funcionales
en el colículo inferior. Las alucinaciones auditivas son uno de los síntomas centrales ...
[EN] Colon targeted drug delivery is highly relevant not only to treat colonic local diseases but also for systemic therapies. Mesoporous silica nanoparticles (MSNs) have been demonstrated as useful systems for controlled ...
Loras, Alba; Suárez-Cabrera, Cristian; Martínez-Bisbal, M.Carmen; Quintás, Guillermo; Paramio, Jesús M.; Martínez-Máñez, Ramón; Gil Grau, Salvador; Ruiz-Cerdá, José Luis(MDPI AG, 2019-05)
[EN] Metabolism reprogramming is considered a hallmark of cancer. The study of bladder cancer (BC) metabolism could be the key to developing new strategies for diagnosis and therapy. This work aimed to identify tissue and ...
Bhat, Ravishankar; García, I.; Aznar, Elena; Arnáiz, B.; Martínez-Bisbal, M.Carmen; Liz-Marzán, L.M.; Penadés, S.; Martínez-Máñez, Ramón(The Royal Society of Chemistry, 2018)
[EN] Gated mesoporous silica nanoparticles can deliver payload upon the application of a predefined stimulus, and therefore are promising drug delivery systems. Despite their important role, relatively low emphasis has ...
[EN] Microalgae play a fundamental role in aquatic primary production and the food chain. They are a recognized source of fatty acids and fatty acid-based lipids of potential interest in the preparation of functional health ...
Lozano-Torres, Beatriz; Martínez-Bisbal, M.Carmen; Soto Camino, Juan; Juan-Borras, María del Sol; Martínez-Máñez, Ramón; Escriche Roberto, Mª Isabel(Elsevier, 2022-07-30)
[EN] Proton-nuclear-magnetic-resonance-spectroscopy (H-1 NMR) is the widely accepted reference method for monitoring honey adulteration; however, the need to find cheaper, faster, and more environmentally friendly methodologies ...
[EN] Automatic brain tumor classification by MRS has been under development for more than a decade. Nonetheless, to our knowledge, there are no published evaluations of predictive models with unseen cases that are subsequently ...
[EN] Bladder cancer (BC) is the sixth leading cause of death by cancer. Depending on the invasiveness of tumors, patients with BC will undergo surgery and surveillance lifelong, owing the high rate of recurrence and ...
Botello Marabotto, Marina Dolores(Universitat Politècnica de València, 2024-11-03)
[ES] La tesis doctoral titulada "NMR-based metabolomics for the identification of biomarkers of disease" explora el potencial de la metabolómica mediante espectroscopía de resonancia magnética nuclear (RMN) para la ...
[EN] Alzheimer's disease is the most common type of dementia in the elderly. It is a progressive degenerative disorder that may begin to develop up to 15 years before clinical symptoms appear. The identification of early ...
Martínez-Bisbal, M. Carmen; Masot Peris, Rafael; Alcañiz Fillol, Miguel(Editorial Universitat Politècnica de València, 2019-09-30)
[EN] In the Master's Degree in Sensors for Industrial Applications of the Universitat
Politècnica de València, the subject "Modeling techniques" is taught.
"Application of multivariate techniques to real experiences" is ...
[EN] Primary Open-Angle Glaucoma (POAG) is the most prevalent glaucoma type, and the leading cause of irreversible visual impairment and blindness worldwide. Identification of early POAG biomarkers is of enormous value, ...
[EN] The role of oxidative stress (OS) in cancer is a matter of great interest due to the implication of reactive oxygen species (ROS) and their oxidation products in the initiation of tumorigenesis, its progression, and ...
Loras, Alba; Martínez-Bisbal, M.Carmen; Quintás, Guillermo; Gil Grau, Salvador; Martínez-Máñez, Ramón; Ruiz-Cerdá, José Luis(MDPI AG, 2019-06-26)
[EN] Patients with non-muscle invasive bladder cancer (NMIBC) undergo lifelong monitoring based on repeated cystoscopy and urinary cytology due to the high recurrence rate of this tumor. Nevertheless, these techniques have ...