BOTELLA ASUNCION, PABLO; Rivero-Buceta, Eva María; VIDAURRE AGUT, CARLA; Lama, Raquel; Rey-Campos, Magalí; Moreno, Alejandro; Mendoza, Laura; Mingo-Casas, Patricia; Escribano-Romero, Estela; Gutiérrez-Adán, Alfonso; Saiz, Juan Carlos; Smerdou, Cristian; Gonzalez, Gloria; Prósper, Felipe; Argemí, Josepmaría; San Miguel, Jesus; Sánchez Cordón, Pedro J.; Figueras, Antonio; Quesada-Gómez, Jose Manuel; Novoa, Beatriz; Montoya, María; Martín-Acebes, Miguel A.; Pineda-Lucena, Antonio; Benlloch Babiera, José María(Elsevier, 2023-11)
[EN] An archetypal anti-inflammatory compound against cytokine storm would inhibit it without suppressing the innate immune response. AG5, an anti-inflammatory compound, has been developed as synthetic derivative of ...
[EN] MIL-100(Fe) and MIL-101(Fe) metal-organic frameworks (MOFs) are excellent vehicles for drug delivery systems (DDSs) due to their high biocompatibility and stability in physiological fluids, as well as their pore ...
Checa-Chavarria, Elisa; Rivero-Buceta, Eva María; Sanchez Martos, Miguel Angel; Martinez Navarrete, Gema; Soto-Sanchez, Cristina; BOTELLA ASUNCION, PABLO; FERNANDEZ JOVER, EDUARDO(American Chemical Society, 2021-04-05)
[EN] A novel therapeutic approach for glioblastoma multiforme (GBM) therapy has been carried out through in vitro and in vivo testing by using the prodrug camptothecin-20-O-(5-aminolevulinate) (CPT-ALA). The incorporation ...
Cabrera-García, Alejandro; Checa-Chavarria, Elisa; Pacheco-Torres, Jesús; Bernabeu-Sanz, Angela; Vidal Moya, José Alejandro; Rivero-Buceta, Eva María; Sastre Navarro, German Ignacio; Fernandez Jover, Eduardo; Botella Asuncion, Pablo(The Royal Society of Chemistry, 2018-04-14)
[EN] The development of contrast agents (CAs) for Magnetic Resonance Imaging (MRI) with T-1-T-2 dual-mode relaxivity requires the accurate assembly of T-1 and T-2 magnetic centers in a single structure. In this context, ...
VIDAURRE AGUT, CARLA MARIA; Rivero-Buceta, Eva María; Landry, Christopher C.; BOTELLA ASUNCION, PABLO(MDPI AG, 2021-05)
[EN] To understand the factors that control the formation of the biomolecular corona, a systematic study of the adsorption of several miRNAs shown to be important in prostate cancer on amine-functionalized mesoporous silica ...
Rivero-Buceta, Eva María; Encheva, Mirela E.; Cech, Bradley; Fernández, Eduardo; SASTRE NAVARRO, GERMAN IGNACIO; Landry, Christopher C.; BOTELLA ASUNCION, PABLO(The Royal Society of Chemistry, 2023-08-03)
[EN] Many systems for controlled drug release have been developed using different types of nanoparticles modified with azobenzene moieties. In these systems, drug release is often triggered by UV irradiation (either direct ...
[EN] Polymeric-inorganic hybrid nanomaterials have emerged as novel multifunctional platforms because they combine the intrinsic characteristics of both materials with unexpected properties that arise from synergistic ...
Rivero-Buceta, Eva María; Bernal-Gómez, Adrián; VIDAURRE-AGUT, CARLA; Lopez Moncholi, Eric; Benlloch Baviera, Jose María; Moreno Manzano, Victoria; Vera Donoso, César David; BOTELLA ASUNCION, PABLO(Elsevier, 2024-10-25)
[EN] Docetaxel (DTX) is a recommended treatment in patients with metastasic prostate cancer (PCa), despite its therapeutic efficacy is limited by strong systemic toxicity. However, in localized PCa, intratumoral (IT) ...
VIDAURRE AGUT, CARLA MARIA; Rivero-Buceta, Eva María; Romaní-Cubells, Eva; CLEMMENTS, ALDEN MICHAEL; VERA DONOSO, CESAR DAVID; Landry, C.C.; BOTELLA ASUNCION, PABLO(American Chemical Society, 2019-05-31)
[EN] Diagnostic tests based on proteomics analysis can have significant advantages over more traditional biochemical tests. However, low molecular weight (MW) protein biomarkers are difficult to identify by standard mass ...
Rivero-Buceta, Eva María; VIDAURRE AGUT, CARLA MARIA; VERA DONOSO, CESAR DAVID; Benlloch Baviera, Jose María; MORENO MANZANO, VICTORIA; BOTELLA ASUNCION, PABLO(American Chemical Society, 2019-01-31)
[EN] Although docetaxel is currently broadly used in prostate cancer treatment, poor water solubility and systemic toxicity limit the dose and duration of therapy. In this context, although different nanoplatforms have ...
BOTELLA ASUNCION, PABLO; Rivero-Buceta, Eva María(Elsevier, 2017-02-10)
[EN] Twenty-(S)-camptothecin is a strongly cytotoxic molecule with excellent antitumor activity over a wide spectrum of human cancers. However, the direct formulation is limited by its poor water solubility, low plasmatic ...
De Santana Oliveira, Artur; Rivero-Buceta, Eva María; Vidaurre-Agut, Carla; Misturini, Alechania; Moreno, Victoria; Jorda Moret, Jose Luis; SASTRE NAVARRO, GERMAN IGNACIO; Castella Pergher, Sibele Berenice; BOTELLA ASUNCION, PABLO(Elsevier, 2020-12)
[EN] Post-synthetic modification of covalent organic frameworks (COFs) is strongly demanded in order to provide additional functionalities to their structures. However, the introduction of functional groups during the ...
[EN] The administration of cytotoxic drugs in classical chemotherapy is frequently limited by water solubility, low plasmatic stability, and a myriad of secondary effects associated with their diffusion to healthy tissue. ...