Buscar en RiuNet

Listar

Todo RiuNet

Mi cuenta

Acceder

Ayuda RiuNet

Admin. UPV

Listar por autor "Sempere Talens, Amparo"

Mostrando ítems 1-10 de 10

3D Culture o Multiple Myeloma Cell Line Using Microgel Environments

Marin Paya, Juan Carlos (Universitat Politècnica de València, 2021-06-03)

[ES] El mieloma múltiple es una neoplasia hematológica caracterizada por una expansión descontrolada de células plasmáticas monoclonales (mPCs) en medula ósea que producen, en la mayoría de los casos, un componente monoclonal ...
Biomimetic 3D environment based on microgels as a model for the generation of drug resistance in multiple myeloma

Marín-Payá, Juan Carlos; Díaz-Benito, Blanca; Amaro Martins, Luis; Clara Trujillo, Sandra; Cordón, Lourdes; Lanceros-Méndez, Senentxu; Gallego-Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís (MDPI AG, 2021-12)

[EN] The development of three-dimensional environments to mimic the in vivo cellular response is a problem in the building of disease models. This study aimed to synthesize and validate three-dimensional support for culturing ...
Biomimetic microspheres for 3D mesenchymal stem cell culture and characterization

Clara-Trujillo, Sandra; Marin-Paya, Juan Carlos; Cordón, Lourdes; Sempere, Amparo; Gallego-Ferrer, Gloria; Gómez Ribelles, José Luís (Elsevier, 2019-05-01)

[EN] Stem cells reside in niches, specialized microenvironments that sustain and regulate their fate. Extracellular matrix (ECM), paracrine factors or other cells are key niche regulating elements. As the conventional 2D ...
Human Mesenchymal Stem Cells Growth and Osteogenic Differentiation on Piezoelectric Poly(vinylidene fluoride) Microsphere Substrates

Sobreiro-Almeida, Rita; Tamaño-Machiavello, María Noel; Carvalho, E.O.; Cordon, Lourdes; Doria, S.; Senent, Leonor; Correia, D. M.; Ribeiro, C.; Lanceros-Méndez, S.; Sabater i Serra, Roser; Gómez Ribelles, José Luís; Sempere-Talens, Amparo (MDPI AG, 2017)

[EN] The aim of this work was to determine the influence of the biomaterial environment on human mesenchymal stem cell (hMSC) fate when cultured in supports with varying topography. Poly(vinylidene fluoride) (PVDF) culture ...
Novel microgel culture system as semi-solid three-dimensional in vitro model for the study of multiple myeloma proliferation and drug resistance

Clara-Trujillo, Sandra; Tolosa, Laia; Cordón, Lourdes; Sempere, Amparo; Gallego-Ferrer, Gloria; Gómez Ribelles, José Luís (Elsevier, 2022-04)

[EN] Multiple myeloma (MM) is a hematological malignancy in which the patient's drug resistance is one of the main clinical problems. As 2D cultures do not recapitulate the cellular microenvironment, which has a key role ...
Osteogenic differentiation of human mesenchymal stem cells on electroactive substrates

Tamaño-Machiavello, María Noel; Carvalho, E.O.; Correia, Daniela; Cordón, Lourdes; Lanceros-Méndez, Senentxu; Sempere, Amparo; Sabater i Serra, Roser; Gómez Ribelles, José Luís (Elsevier, 2024-03-29)

[EN] This study investigates the effect of electroactivity and electrical charge distribution on the biological response of human bone marrow stem cells (hBMSCs) cultured in monolayer on flat poly(vinylidene fluoride), ...
Protein-Functionalized Microgel for Multiple Myeloma Cells' 3D Culture

Marin-Paya, Juan Carlos; Clara-Trujillo, Sandra; Cordón, Lourdes; Gallego-Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís (MDPI AG, 2022-11)

[EN] Multiple myeloma is a hematologic neoplasm caused by an uncontrolled clonal proliferation of neoplastic plasma cells (nPCs) in the bone marrow. The development and survival of this disease is tightly related to the ...
Soportes funcionalizados para cultivo de células madre mesenquimales de médula ósea

Doria Belenguer, Sergio (Universitat Politècnica de València, 2016-11-24)

[ES] El objetivo del trabajo es el desarrollo de soportes piezoeléctricos para el cultivo celular tanto en monocapa como en entornos tridimensionales. El polifluoruro de vinilideno, PVDF, puede cristalizarse en la fase ...
Stability of Biomimetically Functionalised Alginate Microspheres as 3D Support in Cell Cultures

García Briega, María Inmaculada; Ródenas Rochina, Joaquín; Ribeiro Martins, Luis Amaro; Gallego Ferrer, Gloria; Lanceros-Mendez, Senentxu; Sempere Talens, Amparo; Gómez Ribelles, José Luís (MDPIUniversitat Politècnica de València, 2022-10-11)

Alginate hydrogels can be used to develop a three-dimensional environment in which various cell types can be grown. Cross-linking the alginate chains using reversible ionic bonds opens up great possibilities for the ...
Stability of Biomimetically Functionalised Alginate Microspheres as 3D Support in Cell Cultures

García-Briega, María Inmaculada; Ródenas Rochina, Joaquín; Ribeiro-Martins, Luis Amaro; Lanceros-Méndez, Senentxu; Gallego-Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís (MDPI AG, 2022-10)

[EN] Alginate hydrogels can be used to develop a three-dimensional environment in which various cell types can be grown. Cross-linking the alginate chains using reversible ionic bonds opens up great possibilities for the ...