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Listar por autor "Lineros Rosa, Mauricio"

Mostrando ítems 1-7 de 7

A Sunscreen-Based Photocage for Carbonyl Groups

Lineros-Rosa, Mauricio; Miranda Alonso, Miguel Ángel; Lhiaubet, Virginie Lyria (John Wiley & Sons, 2020-06-05)

[EN] Photolabile protecting groups (PPGs) have been exploited in a wide range of chemical and biological applications, due to their ability to provide spatial and temporal control over light-triggered activation. In this ...
Experimental and theoretical studies on thymine photodimerization mediated by oxidatively generated DNA lesions and epigenetic intermediates

Lineros-Rosa, Mauricio; Francés-Monerris, Antonio; Monari, Antonio; Miranda Alonso, Miguel Ángel; Lhiaubet, Virginie Lyria (The Royal Society of Chemistry, 2020-11-28)

[EN] Interaction of nucleic acids with light is a scientific question of paramount relevance not only in the understanding of life functioning and evolution, but also in the insurgence of diseases such as malignant skin ...
Novel Oxybenzone Photolabile Protecting Group for Carbonyl Compounds

Fernández, Benjamín Matthew (Universitat Politècnica de València, 2021-10-29)

[ES] Se está estudiando una nueva clase de grupo protector fotolábil (PPG) basada en el uso de filtro solares. Los PPG son unidades químicas que permiten la protección de grupos funcionales y su posterior fotoliberación. ...
Photoinduced intersystem crossing in DNA oxidative lesions and epigenetic intermediates

Francés-Monerris, Antonio; Lineros-Rosa, Mauricio; Miranda Alonso, Miguel Ángel; Lhiaubet, Virginie Lyria; Monari, Antonio (The Royal Society of Chemistry, 2020-04-25)

[EN] The propensity of 5-formyluracil and 5-formylcytosine, i.e. oxidative lesions and epigenetic intermediates, in acting as intrinsic DNA photosensitizers is unraveled by using a combination of molecular modeling, ...
Photoremovable protecting groups for carbonyl compounds of biological interest

Lineros Rosa, Mauricio (Universitat Politècnica de València, 2021-06-10)

[ES] El espectro de la luz solar está compuesto por una amplia gama de radiaciones electromagnéticas las cuales tienen diferentes impactos sobre la vida en la tierra. Entre ellas, las pertenecientes a la región ultravioleta ...
Spectroscopic characterization of dipicolinic acid and its photoproducts as thymine photosensitizers

Nardi, Giacomo; Lineros-Rosa, Mauricio; Palumbo, Fabrizio; Miranda Alonso, Miguel Ángel; Lhiaubet, Virginie Lyria (Elsevier, 2021-01-15)

[EN] Dipicolinic acid (DPA), present in large amount in bacterial spores, has been proposed to act as an endogenous photosensitizer in spore photoproduct formation. The proposed mechanism involves a triplet-triplet energy ...
Triplet stabilization for enhanced drug photorelease from sunscreen-based photocages

Lineros-Rosa, Mauricio; Cuquerella Alabort, Maria Consuelo; Francés-Monerris, Antonio; Monari, Antonio; Miranda Alonso, Miguel Ángel; Lhiaubet, Virginie Lyria (The Royal Society of Chemistry, 2021-04-28)

[EN] Recently, sunscreen-based drug photocages have been introduced to provide UV protection to photoactive drugs, thus increasing their photosafety. Here, combined experimental and theoretical studies performed on a ...