[EN] Alternative splicing (AS) is a highly-regulated post-transcriptional mechanism known to modulate isoform expression within genes and contribute to cell-type identity. However, the extent to which alternative isoforms ...
Estevan Morió, Eva(Universitat Politècnica de València, 2022-09-06)
[ES] Las tecnologías de secuenciación de alto rendimiento de transcriptomas mediante lecturas largas han facilitado el descubrimiento de nuevos transcritos. No obstante, dichas tecnologías tienen una tasa de error muy ...
[EN] Retinitis pigmentosa (RP) is a rare, progressive disease that affects photoreceptors and retinal pigment epithelial (RPE) cells with blindness as a final outcome. Despite high medical and social impact, there is ...
Arzalluz Luque, Ángeles(Universitat Politècnica de València, 2024-04-27)
[ES] La introducción de la secuenciación de ARN a nivel de célula única (scRNA-seq) en el ámbito de la transcriptómica ha redefinido nuestro entendimiento de la diversidad celular, arrojando luz sobre los mecanismos ...
[EN] Multi-omics approaches have become a reality in both large genomics projects and small laboratories. However, the multi-omics research community still faces a number of issues that have either not been sufficiently ...