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Listar por autor "Álvarez Torres, Maria del Mar"

Mostrando ítems 1-11 de 11

Characterization of vascular heterogeneity of astrocytomas grade 4 for supporting patient prognosis estimation, and treatment response assessment

Álvarez Torres, Maria del Mar (Universitat Politècnica de València, 2022-10-31)

[ES] Los tumores cerebrales son una de las enfermedades más devastadoras en la actualidad por el importante deterioro cognitivo que sufren los pacientes, la elevada tasa de mortalidad y el mal pronóstico. Los astrocitomas ...
Differential effect of vascularity between long- and short-term survivors with IDH1/2 wild-type glioblastoma

Álvarez-Torres, María del Mar; Fuster García, Elíes; Reynes, Gaspar; Juan-Albarracín, Javier; Chelebian-Kocharyan, Eduard Artur; Oleaga, Laura; Pineda, Jose; Auger, Cristina; Rovira, Alex; Emblem, Kyrre E.; Filice, Silvano; Molla-Olmos, Enrique; Garcia-Gomez, Juan M (John Wiley & Sons, 2021-04)

[EN] Introduction: IDH1/2 wt glioblastoma (GB) represents the most lethal tumour of the central nervous system. Tumour vascularity is associated with overall survival (OS), and the clinical relevance of vascular markers, ...
Diseño de software para obtener la interacción toxicológica entre fármacos en pacientes con enfermedades crónicas

Vázquez Bautista, Sergio (Universitat Politècnica de València, 2021-10-05)

[ES] Actualmente existe una falta de información en cuanto a la interacción toxicológica entre fármacos y la ausencia de herramientas que puedan ofrecer esta información. El objetivo específico del proyecto es predecir ...
High-Grade Glioma Treatment Response Monitoring Biomarkers: A Position Statement on the Evidence Supporting the Use of Advanced MRI Techniques in the Clinic, and the Latest Bench-to-Bedside Developments. Part 1: Perfusion and Diffusion Techniques

Henriksen, Otto M.; Álvarez-Torres, María del Mar; Figueiredo, Patricia; Hangel, Gilbert; Keil, Vera C.; Nechifor, Ruben E.; Riemer, Frank; Schmainda, Kathleen M.; Warnert, Esther A. H.; Wiegers, Evita C.; Booth, Thomas C. (Frontiers Media SA, 2022-03-03)

[EN] Objective: Summarize evidence for use of advanced MRI techniques as monitoring biomarkers in the clinic, and highlight the latest bench-to-bedside developments. Methods: Experts in advanced MRI techniques applied to ...
High-Grade Glioma Treatment Response Monitoring Biomarkers: A Position Statement on the Evidence Supporting the Use of Advanced MRI Techniques in the Clinic, and the Latest Bench-to-Bedside Developments. Part 2: Spectroscopy, Chemical Exchange Saturation, Multiparametric Imaging, and Radiomics

Booth, Thomas C.; Wiegers, Evita C.; Warnert, Esther A. H.; Schmainda, Kathleen M.; Riemer, Frank; Nechifor, Ruben E.; Keil, Vera C.; Hangel, Gilbert; Figueiredo, Patrícia; Álvarez-Torres, María del Mar; Henriksen, Otto M. (Frontiers Media SA, 2022-02-28)

[EN] ObjectiveTo summarize evidence for use of advanced MRI techniques as monitoring biomarkers in the clinic, and to highlight the latest bench-to-bedside developments. MethodsThe current evidence regarding the potential ...
Higher vascularity at infiltrated peripheral edema differentiates proneural glioblastoma subtype

Chelebian, Eduard; Fuster García, Elíes; Álvarez-Torres, María del Mar; Juan-Albarracín, Javier; Garcia-Gomez, Juan M (Public Library of Science, 2020-10-14)

[EN] Background and purpose Genetic classifications are crucial for understanding the heterogeneity of glioblastoma. Recently, perfusion MRI techniques have demonstrated associations molecular alterations. In this work, ...
Lack of Benefit of Extending Temozolomide Treatment in Patients with High Vascular Glioblastoma with Methylated MGMT

Álvarez-Torres, María del Mar; Fuster García, Elíes; Balaña, Carmen; Puig, Josep; Garcia-Gomez, Juan M (MDPI AG, 2021-11)

[EN] Despite the complete treatment with surgery, chemotherapy and radiotherapy, patients with glioblastoma have a devasting prognosis. Although the role of extending temozolomide treatment has been explored, the results ...
Local detection of microvessels in IDH-wildtype glioblastoma using relative cerebral blood volume: an imaging marker useful for astrocytoma grade 4 classification

Álvarez-Torres, María del Mar; Fuster García, Elíes; Juan-Albarracín, Javier; Reynes, Gaspar; Aparici-Robles, Fernando; Ferrer Lozano, Jaime; Garcia-Gomez, Juan M (Springer (Biomed Central Ltd.), 2022-01-06)

[EN] Background The microvessels area (MVA), derived from microvascular proliferation, is a biomarker useful for high-grade glioma classification. Nevertheless, its measurement is costly, labor-intense, and invasive. Finding ...
MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas

Fuster García, Elíes; Lorente Estellés, David; Álvarez-Torres, María del Mar; Juan-Albarracín, Javier; Chelebian-Kocharyan, Eduard Artur; Rovira, Alex; Auger Acosta, Cristina; Pineda, Jose; Oleaga, Laura; Mollá-Olmos, Enrique; Filice, Silvano; Due-Tonnessen, Paulina; Meling, Torstein R.; Emblem, Kyrre E.; Garcia-Gomez, Juan M (Springer-Verlag, 2021-03)

[EN] Objectives To assess the combined role of tumor vascularity, estimated from perfusion MRI, andMGMTmethylation status on overall survival (OS) in patients with glioblastoma. Methods A multicentric international dataset ...
Robust association between vascular habitats and patient prognosis in glioblastoma: an international retrospective multicenter study

Álvarez-Torres, María del Mar; Juan-Albarracín, Javier; Fuster García, Elíes; Bellvís-Bataller, Fuensanta; Lorente, David; Reynés, Gaspar; Font de Mora, Jaime; Aparici-Robles, Fernando; Botella, Carlos; Muñoz-Langa, Jose; Faubel, Raquel; Asensio-Cuesta, Sabina; García-Ferrando, Germán A.; Chelebian, Eduard; Auger, Cristina; Pineda, Jose; Rovira, Alex; Oleaga, Laura; Mollà Olmos, Enrique; Revert, Antonio J.; Tshibanda, Luaba; Crisi, Girolamo; Emblem, Kyrre E.; Martin, Didier; Due-Tønnessen, Paulina; Meling, Torstein R.; Filice, Silvano; Sáez Silvestre, Carlos; Garcia-Gomez, Juan M (John Wiley & Sons, 2020-05)

[EN] Background Glioblastoma (GBM) is the most aggressive primary brain tumor, characterized by a heterogeneous and abnormal vascularity. Subtypes of vascular habitats within the tumor and edema can be distinguished: high ...
Vascular differences between IDH-wildtype glioblastoma and astrocytoma IDH-mutant grade 4 at imaging and transcriptomic levels

Álvarez-Torres, María del Mar; López-Cerdán, Adolfo; Andreu, Zoraida; Vayá, Maria de la Iglesia; Fuster García, Elíes; García-García, Francisco; Garcia-Gomez, Juan M (John Wiley & Sons, 2023-11)

[EN] Global agreement in central nervous system (CNS) tumor classification is essential for predicting patient prognosis and determining the correct course of treatment, as well as for stratifying patients for clinical ...