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Listar por autor "Díez Sánchez, Paula"

Mostrando ítems 1-12 de 12

A glutathione disulfide-sensitive Janus nanomachine controlled by an enzymatic AND logic gate for smart delivery

Mayol, Beatriz; Diez-Sánchez, Paula; Sánchez, Alfredo; De La Torre, Cristina; Villalonga, Anabel; Lucena-Sánchez, Elena; Sancenón Galarza, Félix; Martinez-Ruiz, Paloma; Vilela, Diana; Martínez-Máñez, Ramón; Villalonga, Reynaldo (The Royal Society of Chemistry, 2021-11-18)

[EN] This work describes the assembly of a novel enzyme-controlled nanomachine operated through an AND Boolean logic gate for on-command delivery. The nanodevice was constructed on Au-mesoporous silica Janus nanoparticles ...
An enzyme-controlled Janus nanomachine for on-command dual and sequential release

Pérez-Calabuig, Ana M.; Diez-Sánchez, Paula; Martínez-Ruiz, Paloma; Martínez-Máñez, Ramón; Sánchez, Alfredo; Villalonga, Reynaldo (The Royal Society of Chemistry, 2020-06-14)

[EN] A novel nanomachine for dual and sequential delivery of two different compounds was developed by grafting a thiol group and a pH sensitive beta-cyclodextrin-based gate-like ensemble on acetylcholinesterase-modified ...
Análisis del movimiento de nanomotores basados en micro/nanopartículas para aplicaciones biomédicas

Rodríguez García, Miguel Ramón (Universitat Politècnica de València, 2022-09-05)

[ES] Este proyecto se basa en el análisis del movimiento de nanomotores mediante técnicas de microscopía. Los nanomotores, también conocidos como nanorobots, son sistemas basados en micro/nanopartículas capaces de ...
Ficin-Cyclodextrin-Based Docking Nanoarchitectonics of Self-Propelled Nanomotors for Bacterial Biofilm Eradication

Ziemyte, Migle; Escudero-Noguera, Andrea; Diez-Sánchez, Paula; Ferrer, María D.; Murguía, Jose R.; Martí-Centelles, Vicente; Mira, Alex; Martínez-Máñez, Ramón (American Chemical Society, 2023-05-09)

[EN] Development of bioinspired nanomotors showing effective propulsion and cargo delivery capabilities has attracted much attention in the last few years due to their potential use in biomedical applications. However, ...
Glucose-Responsive Enzyme-Controlled Mesoporous Nanomachine with a Layer-by-Layer Supramolecular Architecture

Jimenez-Falcao, S.; de Luis-Fernández, Beatriz; García-Fernández, Alba; Llopis-Lorente, Antoni; Diez-Sánchez, Paula; Sánchez, Alfredo; Sancenón Galarza, Félix; Martínez-Ruiz, Paloma; Martínez-Máñez, Ramón; Villalonga, Reynaldo (2019-07-25)

[EN] Here we describe the construction of an integrated and pH-sensitive nanomachine with layer-by-layer supramolecular design and enzymatic control for on-command delivery. The nanodevice comprises a first layer of ...
Horseradish Peroxidase-Functionalized Gold Nanoconjugates for Breast Cancer Treatment Based on Enzyme Prodrug Therapy

Vivo-Llorca, Gema; Morella-Aucejo, Ángela; García-Fernández, Alba; Diez-Sánchez, Paula; Llopis-Lorente, Antoni; Orzáez, Mar; Martínez-Máñez, Ramón (Dove Medical Press, 2022-01-26)

[EN] Introduction: Breast cancer has the highest mortality rate among cancers in women. Patients suffering from certain breast cancers, such as triple-negative breast cancer (TNBC), lack effective treatments. This represents ...
Nanomotores Janus autopropulsados para el tratamiento mejorado de enfermedades

Hernández Llorens, María Almudena (Universitat Politècnica de València, 2021-07-30)

[ES] Los avances en la nanotecnología han incentivado la creación de nuevas estrategias terapéuticas que aumenten la eficacia de los fármacos en el tratamiento de enfermedades, como el cáncer. En los últimos años se han ...
Nanomotores Janus de platino y sílice mesoporosa como plataforma para la entrega de fármacos en aplicaciones biomédicas

Escudero Noguera, Andrea (Universitat Politècnica de València, 2024-06-24)

[ES] La tesis doctoral titulada «Nanomotores Janus platino-sílice mesoporosa como plataforma para la entrega de fármacos en aplicaciones biomédicas» se centra en el desarrollo de una nanopartícula multifuncional autopropulsada ...
Study and development of self-propelled nanomotors for anti-inflammatory therapy

Gavrilita, Claudia (Universitat Politècnica de València, 2023-02-24)

[ES] La inflamación es la respuesta natural y esencial del organismo a las señales derivadas del daño tisular o de una infección patógena. La inflamación, que se produce tras una lesión o infección, favorece el ...
Toward chemical communication between nanodevices

Llopis-Lorente, Antoni; Diez-Sánchez, Paula; Sánchez, A.; Marcos Martínez, María Dolores; Sancenón Galarza, Félix; Martinez-Ruiz, Paloma; Villalonga, R.; Martínez-Máñez, Ramón (Elsevier, 2018-02)

[EN] Although many nanodevices have been described in recent years, nanoparticles capable of communicating with each other have been barely reported. Traditional communication technologies cannot be applied on the nanoscale, ...
Toxicological Profiling and Long-Term Effects of Bare, PEGylated- and Galacto-Oligosaccharide-Functionalized Mesoporous Silica Nanoparticles

Barguilla, Irene; Candela-Noguera, Vicente; Oliver, Patrick; Annangi, Balasubramanyan; Diez-Sánchez, Paula; Aznar, Elena; Martínez-Máñez, Ramón; Marcos, R.; Hernández, A.; Marcos Martínez, María Dolores (MDPI AG, 2023-11)

[EN] Mesoporous silica nanoparticles (MSNs) are amongst the most used nanoparticles in biomedicine. However, the potentially toxic effects of MSNs have not yet been fully evaluated, being a controversial matter in research. ...
Ultrafast Directional Janus Pt-Mesoporous Silica Nanomotors for Smart Drug Delivery

Diez-Sánchez, Paula; Lucena-Sánchez, Elena; Escudero-Noguera, Andrea; Llopis-Lorente, Antoni; Villalonga, Reynaldo; Martínez-Máñez, Ramón (American Chemical Society, 2021-03-23)

[EN] Development of bioinspired nanomachines with an efficient propulsion and cargo-towing has attracted much attention in the last years due to their potential biosensing, diagnostics, and therapeutics applications. In ...