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Listar por autor "Medaglia, Serena"

Mostrando ítems 1-7 de 7

Andamios de CaP funcionalizados con compuestos antimicrobianos para favorecer la reparación ósea in vivo

Melitón Barbancho, Sandra (Universitat Politècnica de València, 2020-07-02)

[ES] El creciente número de prótesis utilizadas en la medicina moderna ha mejorado la calidad de vida de muchos pacientes, sin embargo, han surgido nuevos problemas como consecuencia de su uso. Las tasas de infecciones ...
Antibacterial Activity of Linezolid against Gram-Negative Bacteria: Utilization of E-Poly-l-Lysine Capped Silica Xerogel as an Activating Carrier

Guzel Kaya, Gulcihan; Medaglia, Serena; Candela-Noguera, Vicente; Tormo-Mas, María Ángeles; Marcos Martínez, María Dolores; Aznar, Elena; Deveci, Huseyin; Martínez-Máñez, Ramón (MDPI AG, 2020-11)

[EN] In recent times, many approaches have been developed against drug resistant Gram-negative bacteria. However, low-cost high effective materials which could broaden the spectrum of antibiotics are still needed. In this ...
Exploring the Synergy between Nano-Formulated Linezolid and Polymyxin B as a Gram-Negative Effective Antibiotic Delivery System Based on Mesoporous Silica Nanoparticles

Otri, Ismael; Medaglia, Serena; Martínez-Máñez, Ramón; Aznar, Elena; Sancenón Galarza, Félix (MDPI AG, 2024-01)

[EN] Antimicrobial resistance is a current silent pandemic that needs new types of antimicrobial agents different from the classic antibiotics that are known to lose efficiency over time. Encapsulation of antibiotics inside ...
Fluorogenic Detection of Human Serum Albumin Using Curcumin-Capped Mesoporous Silica Nanoparticles

Otri, Ismael; Medaglia, Serena; Aznar, Elena; Sancenón Galarza, Félix; Martínez-Máñez, Ramón (MDPI AG, 2022-02)

[EN] Mesoporous silica nanoparticles loaded with rhodamine B and capped with curcumin are used for the selective and sensitive fluorogenic detection of human serum albumin (HSA). The sensing mesoporous silica nanoparticles ...
Gated Organonanoclays for Large Biomolecules: Controlled Release Triggered by Surfactant Stimulus

Poyatos-Racionero, Elisa; Pérez-Esteve, Édgar; Medaglia, Serena; Aznar, Elena; Barat Baviera, José Manuel; Martínez-Máñez, Ramón; Marcos Martínez, María Dolores; Bernardos Bau, Andrea (MDPI AG, 2022-08)

[EN] The low toxicity and high adsorption capacities of clay minerals make them attractive for controlled delivery applications. However, the number of controlled-release studies in the literature using clay minerals is ...
Remarkable enhancement of cinnamaldehyde antimicrobial activity encapsulated in capped mesoporous nanoparticles: A new "nanokiller" approach in the era of antimicrobial resistance

Morella-Aucejo, Ángela; Medaglia, Serena; Ruiz Rico, María; Martínez-Máñez, Ramón; Marcos Martínez, María Dolores; Bernardos Bau, Andrea (Elsevier, 2024-06)

[EN] Combating antimicrobial resistance is one of the biggest health challenges because of the ineffectiveness of standard biocide treatments. This challenge could be approached using natural products, which have demonstrated ...
Simple Endotoxin Detection Using Polymyxin-B-Gated Nanoparticles

Otri, Ismael; El Sayed, Sameh; Medaglia, Serena; Martínez-Máñez, Ramón; Aznar, Elena; Sancenón Galarza, Félix (John Wiley & Sons, 2019-03-12)

[EN] A nanodevice based on mesoporous silica nanoparticles with rhodamine B in the pore framework, functionalized with carboxylates on the outer surface and capped with the cationic polymyxin B peptide, was used to selectively ...