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Listar por autor "Alvarado Marchena, Luis Fernando"

Mostrando ítems 1-5 de 5

Impact of the Potential m(6) A Modification Sites at the 3 ' UTR of Alfalfa Mosaic Virus RNA3 in the Viral Infection

Alvarado-Marchena, Luis; Martínez-Pérez, Mireya; Úbeda, Jesús R.; Pallás Benet, Vicente; APARICIO HERRERO, FREDERIC (MDPI AG, 2022-08)

[EN] We have previously reported the presence of m(6)A in the AMV (Alfamovirus, Bromoviridae) genome. Interestingly, two of these putative m(6)A-sites are in hairpin (hp) structures in the 3'UTR of the viral RNA3. One site ...
Insights into the Molecular Mechanisms of the N6-Methyladenosine (m6A) Methylation Machinery in the Regulation of the Infection Cycle of RNA Plant Viruses

Alvarado Marchena, Luis Fernando (Universitat Politècnica de València, 2022-09-01)

[ES] La N6-metiladenosina (m6A) es una modificación generalizada en los ARN celulares de diferentes organismos que puede afectar muchos procesos y vías celulares. En las plantas, ocurre mediante un complejo de metilación ...
Mapping of Functional Subdomains in the atALKBH9B m6A-Demethylase Required for Its Binding to the Viral RNA and to the Coat Protein of Alfalfa Mosaic Virus

Alvarado-Marchena, Luis; Marquez-Molins, Joan; Martínez-Pérez, Mireya; APARICIO HERRERO, FREDERIC; Pallás Benet, Vicente (Frontiers Media SA, 2021-07-05)

[EN] N-6-methyladenosine (m(6)A) modification is a dynamically regulated RNA modification that impacts many cellular processes and pathways. This epitranscriptomic methylation relies on the participation of RNA methyltransferases ...
Recent Acquisition of Functional m6A RNA Demethylase Domain in Orchid Ty3/Gypsy Elements

Alvarado-Marchena, Luis; Martínez-Pérez, Mireya; APARICIO HERRERO, FREDERIC; Pallás Benet, Vicente; Maumus, Florian (Frontiers Media SA, 2022-07-04)

[EN] Long terminal repeats (LTR) retrotransposons are transposable elements (TEs) representing major components of most plant genomes. The fixation of additional conserved protein domains in their genomes is considered a ...
The m6A RNA demethylase ALKBH9B plays a critical role for vascular movement of Alfalfa mosaic virus in Arabidopsis

Martínez-Pérez, Mireya; Gómez Mena, María Concepción; Alvarado-Marchena, Luis; Nadi, Riad; Micol, José Luis; Pallás Benet, Vicente; APARICIO HERRERO, FREDERIC (Frontiers Media SA, 2021-10-04)

[EN] The N-6-methyladenosine (m(6)A) pathway has been widely described as a viral regulatory mechanism in animals. We previously reported that the capsid protein (CP) of alfalfa mosaic virus (AMV) interacts with the ...