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Engineering post-transcriptional regulation of gene expression with RNA-binding proteins

Dolcemascolo, Roswitha (Universitat Politècnica de València, 2024-01-23)

[ES] La biología sintética tiene como objetivo diseñar y construir nuevos sistemas biológicos con funciones deseadas. Los circuitos basados en el control transcripcional han tenido preponderancia en este campo tras el ...
Gene regulation by a protein translation factor at the single-cell level

Dolcemascolo, Roswitha; Goiriz, Lucas; Montagud-Martínez, Roser; Rodrigo Tarrega, Guillermo (Public Library of Science, 2022-05-06)

[EN] Gene expression is inherently stochastic and pervasively regulated. While substantial work combining theory and experiments has been carried out to study how noise propagates through transcriptional regulations, the ...
Probing the orthogonality and robustness of the mammalian RNA-binding protein Musashi-1 in Escherichia coli

Dolcemascolo, Roswitha; Ruiz, Raúl; Baldanta, Sara; Goiriz, Lucas; Heras-Hernández, María; Montagud-Martínez, Roser; Rodrigo, Guillermo (BioMed Central, 2024-09-30)

[EN] RNA recognition motifs (RRMs) are widespread RNA-binding protein domains in eukaryotes, which represent promising synthetic biology tools due to their compact structure and efficient activity. Yet, their use in ...

Mostrando ítems 1-3 de 3